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Protein
Submitted name:

Lamina-associated polypeptide 2, isoforms beta/gamma variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Lamina-associated polypeptide 2, isoforms beta/gamma variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei337 – 358HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ59G12
PRIDEiQ59G12

Expressioni

Gene expression databases

GenevisibleiQ59G12 HS

Interactioni

Protein-protein interaction databases

IntActiQ59G12, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ59G12
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 81LEM-likeInterPro annotationAdd BLAST44
Domaini142 – 186LEMInterPro annotationAdd BLAST45

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IT7C Eukaryota
ENOG4111J0N LUCA
HOGENOMiHOG000113280
HOVERGENiHBG000166

Family and domain databases

Gene3Di1.10.720.40, 2 hits
InterProiView protein in InterPro
IPR013146 LEM-like_dom
IPR011015 LEM/LEM-like_dom_sf
IPR003887 LEM_dom
PfamiView protein in Pfam
PF03020 LEM, 1 hit
PF08198 Thymopoietin, 1 hit
SMARTiView protein in SMART
SM00540 LEM, 1 hit
SM01261 Thymopoietin, 1 hit
SUPFAMiSSF63451 SSF63451, 2 hits
PROSITEiView protein in PROSITE
PS50954 LEM, 1 hit
PS50955 LEM_LIKE, 1 hit

Sequencei

Sequence statusi: Fragment.

Q59G12-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
GSEAAARSPA RSKRAGVSGG GKGCGEGASQ IPEMPEFLED PSVLTKDKLK
60 70 80 90 100
SELVANNVTL PAGEQRKDVY VQLYLQHLTA RNRPPLPAGT NSKGPPDFSS
110 120 130 140 150
DEEREPTPVL GSGAAAAGRS RAAVGRKATK KTDKPRQEDK DDLDVTELTN
160 170 180 190 200
EDLLDQLVKY GVNPGPIVGT TRKLYEKKLL KLREQGTESR SSTPLPTISS
210 220 230 240 250
SAENTRQNGS NDSDRYSDNE EDSKIELKLE KREPLKGRAK TPVTLKQRRV
260 270 280 290 300
EHNQVGEKTE ERRVERDILK EMFPYEASTP TGISASCRRP IKGAAGRPLE
310 320 330 340 350
LSDFRMEESF SSKYVPKYVP LADVKSEKTK KGRSIPVWIK ILLFVVVAVF
360 370
LFLVYQAMET NQVNPFSNFL HVDPRKSN
Length:378
Mass (Da):41,806
Last modified:April 26, 2005 - v1
Checksum:iD73087A941C65F75
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209297 mRNA Translation: BAD92534.1
RefSeqiNP_001027454.1, NM_001032283.2
NP_001027455.1, NM_001032284.2
UniGeneiHs.11355

Genome annotation databases

GeneIDi7112
KEGGihsa:7112

Similar proteinsi

Entry informationi

Entry nameiQ59G12_HUMAN
AccessioniPrimary (citable) accession number: Q59G12
Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: February 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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