UniProtKB - Q59EK3 (Q59EK3_HUMAN)
Protein
Submitted name:
Adaptor-related protein complex 1, mu 1 subunit variant
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- intracellular protein transport Source: InterPro
- vesicle-mediated transport Source: InterPro
Keywordsi
Biological process | TransportARBA annotation |
Enzyme and pathway databases
SignaLinki | Q59EK3 |
Names & Taxonomyi
Protein namesi | Submitted name: Adaptor-related protein complex 1, mu 1 subunit variantImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- clathrin adaptor complex Source: InterPro
Keywords - Cellular componenti
MembraneARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 199 – 464 | MHDInterPro annotationAdd BLAST | 266 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 28 | DisorderedSequence analysisAdd BLAST | 28 |
Sequence similaritiesi
Belongs to the adaptor complexes medium subunit family.ARBA annotation
Phylogenomic databases
OMAi | GGNKEFL |
OrthoDBi | 725236at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR036168, AP2_Mu_C_sf IPR001392, Clathrin_mu IPR018240, Clathrin_mu_CS IPR011012, Longin-like_dom_sf IPR028565, MHD |
Pfami | View protein in Pfam PF00928, Adap_comp_sub, 1 hit |
PIRSFi | PIRSF005992, Clathrin_mu, 2 hits |
PRINTSi | PR00314, CLATHRINADPT |
SUPFAMi | SSF49447, SSF49447, 1 hit SSF64356, SSF64356, 1 hit |
PROSITEi | View protein in PROSITE PS00990, CLAT_ADAPTOR_M_1, 1 hit PS00991, CLAT_ADAPTOR_M_2, 1 hit PS51072, MHD, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q59EK3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GGARPCSTPS SPHRRCRRHR PRPLPRPPAA IMSASAVYVL DLKGKVLICR
60 70 80 90 100
NYRGDVDMSE VEHFMPILME KEEEGMLSPI LAHGGVRFMW IKHNNLYLVA
110 120 130 140 150
TSKKNACVSL VFSFLYKVVQ VFSEYFKELE EESIRDNFVI IYELLDELMD
160 170 180 190 200
FGYPQTTDSK ILQEYITQEG HKLETGAPRP PATVTNAVSW RSEGIKYRKN
210 220 230 240 250
EVFLDVIESV NLLGKYPGVG WLGHTVSANG NVLRSEIVGS IKMRVFLSGM
260 270 280 290 300
PELRLGLNDK VLFDNTGRGK SKSVELEDVK FHQCVRLSRF ENDRTISFIP
310 320 330 340 350
PDGEFELMSY RLNTHVKPLI WIESVIEKHS HSRIEYMIKA KSQFKRRSTA
360 370 380 390 400
NNVEIHIPVP NDADSPKFKT TVGSVKWVPE NSEIVWSIKS FPGGKEYLMR
410 420 430 440 450
AHFGLPSVEA EDKEGKPPIS VKFEIPYFTT SGIQVRYLKI IEKSGYQALP
460
WVRYITQNGD YQLRTQ
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB209808 mRNA Translation: BAD93045.1 |
RefSeqi | NP_001123996.1, NM_001130524.1 |
Genome annotation databases
GeneIDi | 8907 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB209808 mRNA Translation: BAD93045.1 |
RefSeqi | NP_001123996.1, NM_001130524.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q59EK3, 1 interactor |
Protocols and materials databases
DNASUi | 8907 |
Genome annotation databases
GeneIDi | 8907 |
Organism-specific databases
CTDi | 8907 |
PharmGKBi | PA24848 |
Phylogenomic databases
OMAi | GGNKEFL |
OrthoDBi | 725236at2759 |
Enzyme and pathway databases
SignaLinki | Q59EK3 |
Miscellaneous databases
BioGRID-ORCSi | 8907, 26 hits in 995 CRISPR screens |
GenomeRNAii | 8907 |
Gene expression databases
Genevisiblei | Q59EK3, HS |
Family and domain databases
InterProi | View protein in InterPro IPR036168, AP2_Mu_C_sf IPR001392, Clathrin_mu IPR018240, Clathrin_mu_CS IPR011012, Longin-like_dom_sf IPR028565, MHD |
Pfami | View protein in Pfam PF00928, Adap_comp_sub, 1 hit |
PIRSFi | PIRSF005992, Clathrin_mu, 2 hits |
PRINTSi | PR00314, CLATHRINADPT |
SUPFAMi | SSF49447, SSF49447, 1 hit SSF64356, SSF64356, 1 hit |
PROSITEi | View protein in PROSITE PS00990, CLAT_ADAPTOR_M_1, 1 hit PS00991, CLAT_ADAPTOR_M_2, 1 hit PS51072, MHD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q59EK3_HUMAN | |
Accessioni | Q59EK3Primary (citable) accession number: Q59EK3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 26, 2005 |
Last sequence update: | April 26, 2005 | |
Last modified: | April 7, 2021 | |
This is version 102 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |