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Entry version 123 (16 Oct 2019)
Sequence version 1 (26 Apr 2005)
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Protein
Submitted name:

Neurofibromin 1, isoform D

Gene

Nf1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Neurofibromin 1, isoform DImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nf1Imported
Synonyms:Dmel\CG8318Imported, dNF1Imported, dNf1Imported, FBpp0084326Imported, NF-1Imported, Nf-1Imported, NF1Imported, nf1Imported
ORF Names:CG8318Imported, Dmel_CG8318Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0015269 Nf1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q59DT9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0015269 Expressed in 27 organ(s), highest expression level in head

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q59DT9 differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q59DT9 DM

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q59DT9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1279 – 1475Ras-GAPInterPro annotationAdd BLAST197
Domaini1611 – 1769CRAL-TRIOInterPro annotationAdd BLAST159

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni292 – 315DisorderedSequence analysisAdd BLAST24
Regioni2560 – 2589DisorderedSequence analysisAdd BLAST30
Regioni2733 – 2764DisorderedSequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi292 – 308PolyampholyteSequence analysisAdd BLAST17
Compositional biasi2745 – 2764PolarSequence analysisAdd BLAST20

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1826 Eukaryota
ENOG410XRPJ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00550000074797

KEGG Orthology (KO)

More...
KOi
K08052

Database of Orthologous Groups

More...
OrthoDBi
9686at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00170 SEC14, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit
3.40.525.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR011993 PH-like_dom_sf
IPR039360 Ras_GTPase
IPR001936 RasGAP_dom
IPR008936 Rho_GTPase_activation_prot

The PANTHER Classification System

More...
PANTHERi
PTHR10194 PTHR10194, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13716 CRAL_TRIO_2, 1 hit
PF00616 RasGAP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00323 RasGAP, 1 hit
SM00516 SEC14, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48350 SSF48350, 1 hit
SSF48371 SSF48371, 2 hits
SSF52087 SSF52087, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50191 CRAL_TRIO, 1 hit
PS50018 RAS_GTPASE_ACTIV_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q59DT9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTQKPGEWAS ALLARFEDQL PNRIGAYGTQ ARMSQDQLVA CLIHISRYRF
60 70 80 90 100
SLVISGLTKM LQRVNEAALQ NRHEPERCYF ESLVIILTTL ERCLTNQTKD
110 120 130 140 150
TARFEEAMNV KLLLREISQF VDVQSDSNPN AAQLKALASK VLFALSQNHF
160 170 180 190 200
SAVFNRISAR IQELTSCSEE NPDYNDIELI QHIDMDMIKL TKLLQETITK
210 220 230 240 250
FRSKRAPPLI LLYSLEKAIW NWIEYHPQEF QDLQRGTNRD ISTCWEPLMD
260 270 280 290 300
FVEYFKTENK KSKTLVWPLQ MLLLILNPSC LEAVVNELQQ SEKEKEKDKE
310 320 330 340 350
KVASKSAQST SRDKDFSAKQ FIESIKRGLG QHSPSKQVTE SAAIACVKLC
360 370 380 390 400
KASTYINNTD SNNVVFKLVQ FFINDLKALL FNPAKPFSRG QGYNFADIEL
410 420 430 440 450
MIDCWVSCFR INPHNIEALK VCLNLSSPQA YHFVIVCSLL RLAHIYVDFR
460 470 480 490 500
LQNKNPFRIV NQPRLSWWPQ TDVVHYRSAE LRALFTDTLN KATQGYIAHT
510 520 530 540 550
PLRYITSLTL KSKDTQKGLT RAEEGPAHKM LLLLLVRLIH ADPTLLLNTQ
560 570 580 590 600
GKVAHEVQSS TLELINGLVS LVHQTTMPDV AQEAMEALLA LHAPEKIEVW
610 620 630 640 650
NPEAPINTFW DVSSQVLFSI SQKLIQHQIA NYTDVLKWLR EILICRNTFL
660 670 680 690 700
QRHKDYAHVG SQIAICKQAH IKMEVVFFMY LWSVDLDAVL TSLSCFGLLC
710 720 730 740 750
EEAEICCSSD ELTVGFIMPN YHIYQELAQL STSATDSRIC FFDNTHGNVL
760 770 780 790 800
SRLTLQKRIM TLLRKIEHCV HGVQPAWEET FRNWEVSSKV LQTYPKCKGE
810 820 830 840 850
DGQAEVFHRG MGKRRASHQS SEHDLEEQIN EWANMTWFLL ALGGVCLHKR
860 870 880 890 900
SSSRQMLLQQ SQNNASLGSL AQNSLYSSST SSGHGSLHPS TVSLSTLPPA
910 920 930 940 950
PPQDVSYCPV TQFVGQLLRL LVCSNEKIGL NIQKNVKELV GEEMSTQLYP
960 970 980 990 1000
ILFDQVRAIV EKFFDQQGQV NVNVTDINTQ FIEHTIYIMK SILDPKANKD
1010 1020 1030 1040 1050
PNNDQPSPSE HLGVTSIEGM MLGIVRYVRH LDMTVYAIRI KTKLCQLVEV
1060 1070 1080 1090 1100
MMKRRDDLAF RQEMKFRNKL VEYLTDWVMG TSHQIAPPSS ADAAILTNTS
1110 1120 1130 1140 1150
LIFRDLDQAC MEAVAALLRG LPLQPEESDR GDLMDAKSAL FLKYFTLFMN
1160 1170 1180 1190 1200
LLNDCIDSSE AEKEMNNTPL LPPRPRMAAG KLTALRNATI LAMSNLLGAN
1210 1220 1230 1240 1250
IDSGLMHSID LGYNPDLQTR AAFMEVLTQI LQQGTEFDTL AETVLADRFE
1260 1270 1280 1290 1300
QLVQLVTMIS DKGELPIAMA LANVVTTSQM DELARVLVTL FDAKHLLSPL
1310 1320 1330 1340 1350
LWNMFYREVE VSDCMQTLFR GNSLGSKIMA FCFKIYGASY LQMLLEPLIR
1360 1370 1380 1390 1400
PLLDEEEETC FEVDPARLDP TEDIEQHRNN LIALTQKVFD AIINSSDRFP
1410 1420 1430 1440 1450
PQLRSMCHCL YQVLSKRFPN LLQNNIGAVG TVIFLRFINP AIVSPQELGI
1460 1470 1480 1490 1500
VDKQVHSSAK RGLMLMSKIL QNIANHVEFS KEQHMLCFND FLRDHFEAGR
1510 1520 1530 1540 1550
RFFIQIASDC ETVDQTSHSM SFISDANVLA LHRLLWTHQE KIGDYLSSSR
1560 1570 1580 1590 1600
DHKAVGRRPF DKMATLLAYL GPPEHKPVDS HMMFSSYARW SSIDMSSTNF
1610 1620 1630 1640 1650
EEIMVKHQMH EKEEFKTLKS MNIFYQAGTS KSGYPVFYYI ARRYKIGETN
1660 1670 1680 1690 1700
GDLLIYHVIL TLKPFCHSPF EVVIDFTHTC SDNRFRTEFL QKWFYVLPTV
1710 1720 1730 1740 1750
AYENVHAVYI YNCNSWVREY TKFHDRILAP LKGNRKLLFL ESPNKLTDFI
1760 1770 1780 1790 1800
DAEQQKLPGA TLSLDEDLKV FSNALKLSHK DTKVAIKVGP TALQITSAEK
1810 1820 1830 1840 1850
TKVLAHSVLL NDVYYASEIE EVCLVDDNQF TLSITNESGQ LSFIHNDCDN
1860 1870 1880 1890 1900
IVQAIIHIRN RWELSQPDSV TVHQKIRPKD VPGTLLNMAL LNLGSCDPNL
1910 1920 1930 1940 1950
RTAAYNLLCA LTATFDLKIE GQLLETQGLC IPSNNTIFIK SVSEKLATNE
1960 1970 1980 1990 2000
PHLTLEFLEE SIQGFQRSTI ELKHLCLEYM TPWLKNLVKF CKSNDDSKKL
2010 2020 2030 2040 2050
KVSQILDKLI NLTIDQKEMY PSVQAKIWGS IGQIPELIDM VLDNFLHKSI
2060 2070 2080 2090 2100
TYGLGSPQVE IMADTAVALA SANVQLVSKK VITRICRVMD KSCTNPTQYL
2110 2120 2130 2140 2150
EQHMMWDDIA ILGRYLLMLS FNNCLDVATS VPYLFHTITF LVCSGSLSMR
2160 2170 2180 2190 2200
ASTHGLVINI IHSLCTCTNP SFSEEAQRVL RLSLDEFSLP KFYLLFGISK
2210 2220 2230 2240 2250
VKSAAVTAFR SSCRHPTDKW LGNERVTQPL PADRERLSLP SLEVITDALL
2260 2270 2280 2290 2300
EIMEACMRDV PDCEWLNTWT SLARSFAFCY NPALQPRALI VYGCISKSVT
2310 2320 2330 2340 2350
DHEVKQLLRI LVKALESFND LILIEALVMC LTRIQPLLRP ESPIHRALFW
2360 2370 2380 2390 2400
VAISVLQLDE ITLYGAGLAL LEQNLHTLKS QGCFDKKETI AEVMMKTREK
2410 2420 2430 2440 2450
LEWHFKQLDH AVGLSFRSNF HFALVGHLIK GFRHPTPTTV SRTSRVLTML
2460 2470 2480 2490 2500
LGIIAKPLHR DKFEVTPDSV AYLTALVAVS EEVRSRCHVK HALPRWPADL
2510 2520 2530 2540 2550
SSSVENGEAS GGVQAIGLPL SRRQKSWDIL DQSALQFARQ HKVPTLQNAR
2560 2570 2580 2590 2600
VLFKTQRSFS VPTTKDPNNA TGIEERQERG SRSSVSNESN VLLDPEVLPD
2610 2620 2630 2640 2650
LSIQALVLTV LATLVKYSSD EGETRVLYQY LAEGSVVFPK VFPVIHSLLD
2660 2670 2680 2690 2700
QKINNILSVS HDQVVLNSVQ NIIQNMLASE DPSQQQLHFL QSCGFGGLWR
2710 2720 2730 2740 2750
FAGPFTKYNM MGESSELFVN CLEAMVETCL PGDESAPVPP SPRPYNLSSS
2760
LSSLTLGSPT DKAA
Length:2,764
Mass (Da):312,975
Last modified:April 26, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5789DDF1084CDE70
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9VBJ2Q9VBJ2_DROME
Neurofibromin 1, isoform B
Nf1 Dmel\CG8318, dNF1, dNf1, FBpp0084326, NF-1
2,802Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8IMS2Q8IMS2_DROME
Neurofibromin 1, isoform C
Nf1 Dmel\CG8318, dNF1, dNf1, FBpp0084326, NF-1
2,746Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4KHX4A0A0B4KHX4_DROME
Neurofibromin 1, isoform F
Nf1 Dmel\CG8318, dNF1, dNf1, FBpp0084326, NF-1
2,734Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4KI28A0A0B4KI28_DROME
Neurofibromin 1, isoform E
Nf1 Dmel\CG8318, dNF1, dNf1, FBpp0084326, NF-1
2,793Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAX52994.1

NCBI Reference Sequences

More...
RefSeqi
NP_001014668.1, NM_001014668.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0100113; FBpp0100151; FBgn0015269

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
43149

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG8318

UCSC genome browser

More...
UCSCi
CG8318-RD d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAX52994.1
RefSeqiNP_001014668.1, NM_001014668.2

3D structure databases

SMRiQ59DT9
ModBaseiSearch...

Proteomic databases

PRIDEiQ59DT9

Genome annotation databases

EnsemblMetazoaiFBtr0100113; FBpp0100151; FBgn0015269
GeneIDi43149
KEGGidme:Dmel_CG8318
UCSCiCG8318-RD d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4763
FlyBaseiFBgn0015269 Nf1

Phylogenomic databases

eggNOGiKOG1826 Eukaryota
ENOG410XRPJ LUCA
GeneTreeiENSGT00550000074797
KOiK08052
OrthoDBi9686at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Nf1 fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
43149

Gene expression databases

BgeeiFBgn0015269 Expressed in 27 organ(s), highest expression level in head
ExpressionAtlasiQ59DT9 differential
GenevisibleiQ59DT9 DM

Family and domain databases

CDDicd00170 SEC14, 1 hit
Gene3Di2.30.29.30, 1 hit
3.40.525.10, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR011993 PH-like_dom_sf
IPR039360 Ras_GTPase
IPR001936 RasGAP_dom
IPR008936 Rho_GTPase_activation_prot
PANTHERiPTHR10194 PTHR10194, 1 hit
PfamiView protein in Pfam
PF13716 CRAL_TRIO_2, 1 hit
PF00616 RasGAP, 1 hit
SMARTiView protein in SMART
SM00323 RasGAP, 1 hit
SM00516 SEC14, 1 hit
SUPFAMiSSF48350 SSF48350, 1 hit
SSF48371 SSF48371, 2 hits
SSF52087 SSF52087, 1 hit
PROSITEiView protein in PROSITE
PS50191 CRAL_TRIO, 1 hit
PS50018 RAS_GTPASE_ACTIV_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ59DT9_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q59DT9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: October 16, 2019
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
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