UniProtKB - Q58EF6 (Q58EF6_DANRE)
Protein
Submitted name:
Zgc:113343
Gene
zgc:113343
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zgc:113343ImportedSubmitted name: Zgc:113343 proteinImported |
Gene namesi | ORF Names:zgc:113343Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-050327-90, zgc:113343 |
Subcellular locationi
Nucleus
- nucleus Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSDARG00000103196, Expressed in multi-cellular organism and 26 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 48 – 75 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 76 – 103 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 104 – 131 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 132 – 159 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 160 – 187 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 188 – 214 | C2H2-typeInterPro annotationAdd BLAST | 27 | |
Domaini | 215 – 242 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 243 – 270 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 271 – 298 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 299 – 326 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 327 – 351 | C2H2-typeInterPro annotationAdd BLAST | 25 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 41 | DisorderedSequence analysisAdd BLAST | 41 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 15 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 22 – 37 | PolarSequence analysisAdd BLAST | 16 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000154308 |
HOGENOMi | CLU_002678_44_0_1 |
OMAi | CCECRIS |
OrthoDBi | 1318335at2759 |
TreeFami | TF350834 |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 8 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 11 hits |
SUPFAMi | SSF57667, SSF57667, 6 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 10 hits PS50157, ZINC_FINGER_C2H2_2, 11 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q58EF6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
METEEEPCRI KEEETEEQID ADENAVSSQT EDTSRPKQAG RTAVEGSFIC
60 70 80 90 100
SECGKSYKSK DSLYRHTRFH SGQGLFTCTQ CGKDFVQKGQ LDKHMRIHTG
110 120 130 140 150
ERPYACSQCG KSYNDAATLK MHTKTHSGEK PFTCIQCGKS FIYRKTLKDH
160 170 180 190 200
QLSHNAVKPF SCDQCSKAFT LEKYLRQHLH VHAAVKPYVC FCGKSYTTMN
210 220 230 240 250
MLNEHQRIHT GEKLYQCSHC AKNFTYSNSL KVHQRIHTGE KPYRCSSCGK
260 270 280 290 300
SFTQLASLKA HQRIHTGVKP YVCSDCGKSF STSSSLTAHR RIHTGEKPYQ
310 320 330 340 350
CSHCGKSFNR TGGLKDHQKV HTGEKPHQCS SCGKSFTQMS NLRVHIEKIH
SPKLLE
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A0J9YJ64 | A0A0J9YJ64_DANRE | Zgc:113343 | zgc:113343 | 228 | Annotation score: | ||
A0A0R4IIU5 | A0A0R4IIU5_DANRE | Zgc:113343 | zgc:113343 | 141 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX510922 Genomic DNA No translation available. BC091933 mRNA Translation: AAH91933.1 BC164174 mRNA Translation: AAI64174.1 |
RefSeqi | NP_001014384.1, NM_001014362.1 XP_005160995.1, XM_005160938.3 XP_009293343.1, XM_009295068.2 |
Genome annotation databases
Ensembli | ENSDART00000162725; ENSDARP00000134917; ENSDARG00000103196 |
GeneIDi | 541549 |
KEGGi | dre:541549 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX510922 Genomic DNA No translation available. BC091933 mRNA Translation: AAH91933.1 BC164174 mRNA Translation: AAI64174.1 |
RefSeqi | NP_001014384.1, NM_001014362.1 XP_005160995.1, XM_005160938.3 XP_009293343.1, XM_009295068.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSDART00000162725; ENSDARP00000134917; ENSDARG00000103196 |
GeneIDi | 541549 |
KEGGi | dre:541549 |
Organism-specific databases
ZFINi | ZDB-GENE-050327-90, zgc:113343 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000154308 |
HOGENOMi | CLU_002678_44_0_1 |
OMAi | CCECRIS |
OrthoDBi | 1318335at2759 |
TreeFami | TF350834 |
Gene expression databases
Bgeei | ENSDARG00000103196, Expressed in multi-cellular organism and 26 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 8 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 11 hits |
SUPFAMi | SSF57667, SSF57667, 6 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 10 hits PS50157, ZINC_FINGER_C2H2_2, 11 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q58EF6_DANRE | |
Accessioni | Q58EF6Primary (citable) accession number: Q58EF6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 26, 2005 |
Last sequence update: | April 26, 2005 | |
Last modified: | October 7, 2020 | |
This is version 124 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |