We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - Q58623 (Y1226_METJA)
Protein
Putative cation-transporting ATPase MJ1226
Gene
MJ1226
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Functioni
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 311 | 4-aspartylphosphate intermediateBy similarity | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- ATP hydrolysis activity Source: RHEA
- P-type ion transporter activity Source: GO_Central
- P-type proton-exporting transporter activity Source: InterPro
GO - Biological processi
- ion transmembrane transport Source: GO_Central
- proton export across plasma membrane Source: InterPro
Keywordsi
Molecular function | Translocase |
Ligand | ATP-binding, Nucleotide-binding |
Protein family/group databases
TCDBi | 3.A.3.3.4, the p-type atpase (p-atpase) superfamily |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:MJ1226 |
Organismi | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) |
Taxonomic identifieri | 243232 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Methanomada group › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 53 – 73 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 75 – 95 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 226 – 246 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 258 – 278 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 615 – 637 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 641 – 663 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 680 – 700 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 712 – 734 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 747 – 769 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 773 – 790 | HelicalSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000046427 | 1 – 805 | Putative cation-transporting ATPase MJ1226Add BLAST | 805 |
Keywords - PTMi
PhosphoproteinProteomic databases
PRIDEi | Q58623 |
Family & Domainsi
Sequence similaritiesi
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | arCOG01578, Archaea |
HOGENOMi | CLU_002360_6_4_2 |
InParanoidi | Q58623 |
OMAi | CDGVRYV |
PhylomeDBi | Q58623 |
Family and domain databases
CDDi | cd02076, P-type_ATPase_H, 1 hit |
Gene3Di | 3.40.1110.10, 1 hit 3.40.50.1000, 1 hit |
InterProi | View protein in InterPro IPR004014, ATPase_P-typ_cation-transptr_N IPR023299, ATPase_P-typ_cyto_dom_N IPR018303, ATPase_P-typ_P_site IPR023298, ATPase_P-typ_TM_dom_sf IPR008250, ATPase_P-typ_transduc_dom_A_sf IPR036412, HAD-like_sf IPR023214, HAD_sf IPR006534, P-type_ATPase_IIIA IPR001757, P_typ_ATPase IPR044492, P_typ_ATPase_HD_dom |
Pfami | View protein in Pfam PF00690, Cation_ATPase_N, 1 hit |
PRINTSi | PR00120, HATPASE |
SFLDi | SFLDF00027, p-type_atpase, 1 hit |
SMARTi | View protein in SMART SM00831, Cation_ATPase_N, 1 hit |
SUPFAMi | SSF56784, SSF56784, 1 hit SSF81653, SSF81653, 1 hit SSF81660, SSF81660, 1 hit SSF81665, SSF81665, 1 hit |
TIGRFAMsi | TIGR01647, ATPase-IIIA_H, 1 hit TIGR01494, ATPase_P-type, 2 hits |
PROSITEi | View protein in PROSITE PS00154, ATPASE_E1_E2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q58623-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MWGVVMNVEE IEEEYKTSIK TGLSTEEAKK RLKIYGYNEI PEKKVHPIIK
60 70 80 90 100
FLSYFWNPIA WMIEIAAILS AIIKHWVDFV IILILLLVNG VVGFWEEYKA
110 120 130 140 150
ENVIEFLKQK MALNARVLRD GKWQIIPAKE LVPGDVVRIR IGDIVPADII
160 170 180 190 200
LVDGDYLVVD ESALTGESLP VEKKIGDIAY SGSIVKKGEM TGIVKATGLN
210 220 230 240 250
TYFGKTVKLV EKAEKVSSYQ KMIIKIGDYL IVLAVILIAI MVAVELFRGK
260 270 280 290 300
SLIETAQFAL VLAVSAIPAA MPAVLSITMA IGALNLAKKD AIVKKLVAIE
310 320 330 340 350
ELAGVDILCS DKTGTLTKNQ LVCGEIIALN GFSKEDVVLF AALASREEDA
360 370 380 390 400
DAIDMAILNE AKKLGLMEKI KNYKIKKFIP FDPVIKRTEA EVTNDEEFKV
410 420 430 440 450
SKGAPQVILD LCNADEELRR KVEEIVDKLA ENGYRALGVA VYKNGRWHFA
460 470 480 490 500
GIIPLYDPPR EDAPLAVKKI KELGVIIKMV TGDHVAIAKN IARMLGIGDK
510 520 530 540 550
IISISELLKK LKRGEIKEEK FDEIVEEADG FAEVFPEHKY KIVDSLQKRG
560 570 580 590 600
HLVAMTGDGV NDAPALKKAD CGIAVSNATD AARAAADIVL LSPGISVIVD
610 620 630 640 650
AIQEARRIFQ RMESYVIYRI TETIRILFFV ELCILILGIY PITALMIVLL
660 670 680 690 700
AILNDIPILA IAYDNVVEPK SPVRWRMREI LMLSTALGLS GVVSSFLIFY
710 720 730 740 750
ISDVFLHLTI AELQSFVFLK LILAGHATIF VTRIRDRLWK KPYPSKLLFW
760 770 780 790 800
GVMGTNIIGT IVAAEGIFMA PIGWDLALFM WLYAHVWMLI NDEIKMILLK
RLKID
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L77117 Genomic DNA Translation: AAB99229.1 |
PIRi | A64453 |
Genome annotation databases
EnsemblBacteriai | AAB99229; AAB99229; MJ_1226 |
KEGGi | mja:MJ_1226 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L77117 Genomic DNA Translation: AAB99229.1 |
PIRi | A64453 |
3D structure databases
SMRi | Q58623 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 243232.MJ_1226 |
Protein family/group databases
TCDBi | 3.A.3.3.4, the p-type atpase (p-atpase) superfamily |
Proteomic databases
PRIDEi | Q58623 |
Genome annotation databases
EnsemblBacteriai | AAB99229; AAB99229; MJ_1226 |
KEGGi | mja:MJ_1226 |
Phylogenomic databases
eggNOGi | arCOG01578, Archaea |
HOGENOMi | CLU_002360_6_4_2 |
InParanoidi | Q58623 |
OMAi | CDGVRYV |
PhylomeDBi | Q58623 |
Family and domain databases
CDDi | cd02076, P-type_ATPase_H, 1 hit |
Gene3Di | 3.40.1110.10, 1 hit 3.40.50.1000, 1 hit |
InterProi | View protein in InterPro IPR004014, ATPase_P-typ_cation-transptr_N IPR023299, ATPase_P-typ_cyto_dom_N IPR018303, ATPase_P-typ_P_site IPR023298, ATPase_P-typ_TM_dom_sf IPR008250, ATPase_P-typ_transduc_dom_A_sf IPR036412, HAD-like_sf IPR023214, HAD_sf IPR006534, P-type_ATPase_IIIA IPR001757, P_typ_ATPase IPR044492, P_typ_ATPase_HD_dom |
Pfami | View protein in Pfam PF00690, Cation_ATPase_N, 1 hit |
PRINTSi | PR00120, HATPASE |
SFLDi | SFLDF00027, p-type_atpase, 1 hit |
SMARTi | View protein in SMART SM00831, Cation_ATPase_N, 1 hit |
SUPFAMi | SSF56784, SSF56784, 1 hit SSF81653, SSF81653, 1 hit SSF81660, SSF81660, 1 hit SSF81665, SSF81665, 1 hit |
TIGRFAMsi | TIGR01647, ATPase-IIIA_H, 1 hit TIGR01494, ATPase_P-type, 2 hits |
PROSITEi | View protein in PROSITE PS00154, ATPASE_E1_E2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Y1226_METJA | |
Accessioni | Q58623Primary (citable) accession number: Q58623 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 10, 2003 |
Last sequence update: | November 1, 1996 | |
Last modified: | February 23, 2022 | |
This is version 135 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families