UniProtKB - Q58379 (POK_METJA)
Protein
Pantoate kinase
Gene
MJ0969
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Functioni
Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.UniRule annotation
Catalytic activityi
- EC:2.7.1.169UniRule annotation
: coenzyme A biosynthesis Pathwayi
This protein is involved in the pathway coenzyme A biosynthesis, which is part of Cofactor biosynthesis.UniRule annotationView all proteins of this organism that are known to be involved in the pathway coenzyme A biosynthesis and in Cofactor biosynthesis.
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- kinase activity Source: UniProtKB-UniRule
GO - Biological processi
- coenzyme A biosynthetic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | Kinase, Transferase |
Biological process | Coenzyme A biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | MJAN243232:G1GKE-1058-MONOMER |
UniPathwayi | UPA00241 |
Names & Taxonomyi
Protein namesi | Recommended name: Pantoate kinaseUniRule annotation (EC:2.7.1.169UniRule annotation)Short name: PoKUniRule annotation |
Gene namesi | Ordered Locus Names:MJ0969 |
Organismi | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) |
Taxonomic identifieri | 243232 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Methanomada group › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000107123 | 1 – 270 | Pantoate kinaseAdd BLAST | 270 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | arCOG04263, Archaea |
HOGENOMi | CLU_081191_0_0_2 |
InParanoidi | Q58379 |
OMAi | MLGETVF |
OrthoDBi | 104702at2157 |
PhylomeDBi | Q58379 |
Family and domain databases
Gene3Di | 3.30.230.10, 1 hit |
HAMAPi | MF_02223, Pantoate_kinase, 1 hit |
InterProi | View protein in InterPro IPR006204, GHMP_kinase_N_dom IPR012043, PoK IPR020568, Ribosomal_S5_D2-typ_fold IPR014721, Ribosomal_S5_D2-typ_fold_subgr |
PANTHERi | PTHR42282, PTHR42282, 1 hit |
Pfami | View protein in Pfam PF00288, GHMP_kinases_N, 1 hit |
PIRSFi | PIRSF016896, GHMP_arc_MJ0969, 1 hit |
SUPFAMi | SSF54211, SSF54211, 1 hit |
i Sequence
Sequence statusi: Complete.
Q58379-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFAPGHITGF FVICKSSNKL KTGSIGAGIT IDRGVNVELK EGNGSIFYNN
60 70 80 90 100
KKVNICAVEK VIEHYKKFGY NDDYDIIFSS DFPLGSGLGM SGGCALILAK
110 120 130 140 150
KLNEMLNLNE NYAEIAHISE VECGTGLGDV IAQYVKGFVI RKTPGFPINV
160 170 180 190 200
EKIVVDDDYY IIIEIFGKKE TKEIITNDIW IKKINEYGER CLNELLKNPT
210 220 230 240 250
LENFVNLSYE FAVNTGLINE KILSICEDLK FTVGASQSML GNTLFCISKK
260 270
ETLEDALSIL KNPIVCNIYY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L77117 Genomic DNA Translation: AAB98974.1 |
PIRi | A64421 |
RefSeqi | WP_010870483.1, NC_000909.1 |
Genome annotation databases
EnsemblBacteriai | AAB98974; AAB98974; MJ_0969 |
GeneIDi | 1451867 |
KEGGi | mja:MJ_0969 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L77117 Genomic DNA Translation: AAB98974.1 |
PIRi | A64421 |
RefSeqi | WP_010870483.1, NC_000909.1 |
3D structure databases
SMRi | Q58379 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 243232.MJ_0969 |
Genome annotation databases
EnsemblBacteriai | AAB98974; AAB98974; MJ_0969 |
GeneIDi | 1451867 |
KEGGi | mja:MJ_0969 |
Phylogenomic databases
eggNOGi | arCOG04263, Archaea |
HOGENOMi | CLU_081191_0_0_2 |
InParanoidi | Q58379 |
OMAi | MLGETVF |
OrthoDBi | 104702at2157 |
PhylomeDBi | Q58379 |
Enzyme and pathway databases
UniPathwayi | UPA00241 |
BioCyci | MJAN243232:G1GKE-1058-MONOMER |
Family and domain databases
Gene3Di | 3.30.230.10, 1 hit |
HAMAPi | MF_02223, Pantoate_kinase, 1 hit |
InterProi | View protein in InterPro IPR006204, GHMP_kinase_N_dom IPR012043, PoK IPR020568, Ribosomal_S5_D2-typ_fold IPR014721, Ribosomal_S5_D2-typ_fold_subgr |
PANTHERi | PTHR42282, PTHR42282, 1 hit |
Pfami | View protein in Pfam PF00288, GHMP_kinases_N, 1 hit |
PIRSFi | PIRSF016896, GHMP_arc_MJ0969, 1 hit |
SUPFAMi | SSF54211, SSF54211, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | POK_METJA | |
Accessioni | Q58379Primary (citable) accession number: Q58379 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | November 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 97 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families