We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - Q58083 (H669_METJA)
Protein
Probable ATP-dependent RNA helicase MJ0669
Gene
MJ0669
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Functioni
Catalytic activityi
- EC:3.6.4.13
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 51 – 58 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- ATP hydrolysis activity Source: RHEA
- RNA binding Source: GO_Central
- RNA helicase activity Source: GO_Central
Keywordsi
Molecular function | Helicase, Hydrolase, RNA-binding |
Ligand | ATP-binding, Nucleotide-binding |
Protein family/group databases
REBASEi | 203805, Ppe892ORF686P 205577, Ppe194ORF513P |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:MJ0669 |
Organismi | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) |
Taxonomic identifieri | 243232 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Methanomada group › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000055116 | 1 – 367 | Probable ATP-dependent RNA helicase MJ0669Add BLAST | 367 |
Proteomic databases
PRIDEi | Q58083 |
Interactioni
Subunit structurei
Homodimer.
Protein-protein interaction databases
STRINGi | 243232.MJ_0669 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q58083 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q58083 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 38 – 206 | Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST | 169 | |
Domaini | 213 – 367 | Helicase C-terminalPROSITE-ProRule annotationAdd BLAST | 155 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 6 – 34 | Q motifAdd BLAST | 29 | |
Motifi | 154 – 157 | DEAD box | 4 |
Sequence similaritiesi
Belongs to the DEAD box helicase family.Curated
Phylogenomic databases
eggNOGi | arCOG00558, Archaea |
HOGENOMi | CLU_003041_1_3_2 |
InParanoidi | Q58083 |
OMAi | RNPIRIL |
PhylomeDBi | Q58083 |
Family and domain databases
Gene3Di | 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR011545, DEAD/DEAH_box_helicase_dom IPR014001, Helicase_ATP-bd IPR001650, Helicase_C IPR027417, P-loop_NTPase IPR000629, RNA-helicase_DEAD-box_CS IPR014014, RNA_helicase_DEAD_Q_motif |
Pfami | View protein in Pfam PF00270, DEAD, 1 hit PF00271, Helicase_C, 1 hit |
SMARTi | View protein in SMART SM00487, DEXDc, 1 hit SM00490, HELICc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00039, DEAD_ATP_HELICASE, 1 hit PS51192, HELICASE_ATP_BIND_1, 1 hit PS51194, HELICASE_CTER, 1 hit PS51195, Q_MOTIF, 1 hit |
i Sequence
Sequence statusi: Complete.
Q58083-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEVEYMNFNE LNLSDNILNA IRNKGFEKPT DIQMKVIPLF LNDEYNIVAQ
60 70 80 90 100
ARTGSGKTAS FAIPLIELVN ENNGIEAIIL TPTRELAIQV ADEIESLKGN
110 120 130 140 150
KNLKIAKIYG GKAIYPQIKA LKNANIVVGT PGRILDHINR GTLNLKNVKY
160 170 180 190 200
FILDEADEML NMGFIKDVEK ILNACNKDKR ILLFSATMPR EILNLAKKYM
210 220 230 240 250
GDYSFIKAKI NANIEQSYVE VNENERFEAL CRLLKNKEFY GLVFCKTKRD
260 270 280 290 300
TKELASMLRD IGFKAGAIHG DLSQSQREKV IRLFKQKKIR ILIATDVMSR
310 320 330 340 350
GIDVNDLNCV INYHLPQNPE SYMHRIGRTG RAGKKGKAIS IINRREYKKL
360
RYIERAMKLK IKKLKFG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L77117 Genomic DNA Translation: AAB98663.1 |
PIRi | E64383 |
Genome annotation databases
EnsemblBacteriai | AAB98663; AAB98663; MJ_0669 |
KEGGi | mja:MJ_0669 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L77117 Genomic DNA Translation: AAB98663.1 |
PIRi | E64383 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1HV8 | X-ray | 3.00 | A/B | 1-367 | [»] | |
SMRi | Q58083 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 243232.MJ_0669 |
Protein family/group databases
REBASEi | 203805, Ppe892ORF686P 205577, Ppe194ORF513P |
Proteomic databases
PRIDEi | Q58083 |
Genome annotation databases
EnsemblBacteriai | AAB98663; AAB98663; MJ_0669 |
KEGGi | mja:MJ_0669 |
Phylogenomic databases
eggNOGi | arCOG00558, Archaea |
HOGENOMi | CLU_003041_1_3_2 |
InParanoidi | Q58083 |
OMAi | RNPIRIL |
PhylomeDBi | Q58083 |
Miscellaneous databases
EvolutionaryTracei | Q58083 |
Family and domain databases
Gene3Di | 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR011545, DEAD/DEAH_box_helicase_dom IPR014001, Helicase_ATP-bd IPR001650, Helicase_C IPR027417, P-loop_NTPase IPR000629, RNA-helicase_DEAD-box_CS IPR014014, RNA_helicase_DEAD_Q_motif |
Pfami | View protein in Pfam PF00270, DEAD, 1 hit PF00271, Helicase_C, 1 hit |
SMARTi | View protein in SMART SM00487, DEXDc, 1 hit SM00490, HELICc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00039, DEAD_ATP_HELICASE, 1 hit PS51192, HELICASE_ATP_BIND_1, 1 hit PS51194, HELICASE_CTER, 1 hit PS51195, Q_MOTIF, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | H669_METJA | |
Accessioni | Q58083Primary (citable) accession number: Q58083 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 136 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families