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Protein

Probable tRNA pseudouridine synthase D 1

Gene

truD1

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei92NucleophileUniRule annotation1

GO - Molecular functioni

  • pseudouridine synthase activity Source: GO_Central
  • RNA binding Source: InterPro
  • tRNA pseudouridine synthase activity Source: UniProtKB-EC

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA pseudouridine synthase D 1UniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase D 1UniRule annotation
tRNA-uridine isomerase D 1UniRule annotation
Gene namesi
Name:truD1UniRule annotation
Ordered Locus Names:MJ0588
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomada groupMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001525401 – 392Probable tRNA pseudouridine synthase D 1Add BLAST392

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ_0588

Structurei

3D structure databases

ProteinModelPortaliQ58008
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini167 – 354TRUDUniRule annotationAdd BLAST188

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04252 Archaea
COG0585 LUCA
InParanoidiQ58008
KOiK06176
OMAiLRYERAM
OrthoDBiPOG093Z087N
PhylomeDBiQ58008

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
PIRSFiPIRSF037016 Pseudouridin_synth_euk_prd, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

Q58008-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLNMNKYLT DAYTGGIIKK YPEDFIVEEI TPEGIILEVG KSIEFKDEEN
60 70 80 90 100
WKGNYIHFTL EKRNWTTLDA IREIANRVGK QRKHFGFAGN KDKYAVTTQR
110 120 130 140 150
VGCFNVKLED LMKVKIKGII LRDFQKTNRK IRLGDLWGNR FTIRVREPEL
160 170 180 190 200
KGKELEEALN KLCKLKYFLN YYGVQRFGTT RPITHIVGRF IIERDWEGAF
210 220 230 240 250
HAYCGTPLPY DDKKSKLARE LVDEENFKEA YKKFPKAFFY ERRMIKAYIE
260 270 280 290 300
TGSYQKAFMI LPPYLRCMFI NAYQSYLFNE IINRRFEYGF EPMEGDILID
310 320 330 340 350
NVPSGALFGY KTRFASGIQG EIEREIYERE NLSPEDFKIG EFGSFIGDRR
360 370 380 390
AMIGKIYNMK YWIEDDSYVL QFCLKKGNYA TSVLREFIEK KD
Length:392
Mass (Da):46,320
Last modified:September 26, 2003 - v2
Checksum:iDC00CC533E6E065C
GO

Sequence cautioni

The sequence AAB98579 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA Translation: AAB98579.1 Different initiation.
PIRiD64373

Genome annotation databases

EnsemblBacteriaiAAB98579; AAB98579; MJ_0588
KEGGimja:MJ_0588

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA Translation: AAB98579.1 Different initiation.
PIRiD64373

3D structure databases

ProteinModelPortaliQ58008
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243232.MJ_0588

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB98579; AAB98579; MJ_0588
KEGGimja:MJ_0588

Phylogenomic databases

eggNOGiarCOG04252 Archaea
COG0585 LUCA
InParanoidiQ58008
KOiK06176
OMAiLRYERAM
OrthoDBiPOG093Z087N
PhylomeDBiQ58008

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
PIRSFiPIRSF037016 Pseudouridin_synth_euk_prd, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD1_METJA
AccessioniPrimary (citable) accession number: Q58008
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: September 26, 2003
Last modified: November 7, 2018
This is version 104 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
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