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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Salmonella choleraesuis (strain SC-B67)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei27SubstrateUniRule annotation1
Active sitei80NucleophileUniRule annotation1
Binding sitei129SubstrateUniRule annotation1
Binding sitei329SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:SCH_2860
OrganismiSalmonella choleraesuis (strain SC-B67)
Taxonomic identifieri321314 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000000538 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002301501 – 349tRNA pseudouridine synthase DAdd BLAST349

Structurei

3D structure databases

ProteinModelPortaliQ57KJ6
SMRiQ57KJ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 303TRUDUniRule annotationAdd BLAST149

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

KOiK06176
OMAiLWLWVEK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

Q57KJ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEFDNLTWL HGKPQGSGLL KANPEDFVVV EDLGFTPDGE GEHILLRILK
60 70 80 90 100
NGCNTRFVAD ALAKFLKIHA REVSFAGQKD KHAVTEQWLC ARVPGKEMPD
110 120 130 140 150
FSAFQLEGCK VLEYARHKRK LRLGALKGNA FTLVLREISD RRDVETRLQA
160 170 180 190 200
IRDGGVPNYF GAQRFGIGGS NLQGALRWAQ SNAPVRDRNK RSFWLSAARS
210 220 230 240 250
ALFNQIVHQR LKKPDFNQVV DGDALQLAGR GSWFVATSEE LPELQRRVDE
260 270 280 290 300
KELMITASLP GSGEWGTQRA ALAFEQDAIA QETVLQSLLL REKVEASRRA
310 320 330 340
MLLYPQQLSW NWWDDVTVEL RFWLPAGSFA TSVVRGLINT MGDYAHIAE
Length:349
Mass (Da):39,261
Last modified:May 10, 2005 - v1
Checksum:i5357437747CFD051
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017220 Genomic DNA Translation: AAX66766.1
RefSeqiWP_011264373.1, NC_006905.1

Genome annotation databases

EnsemblBacteriaiAAX66766; AAX66766; SCH_2860
KEGGisec:SCH_2860

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017220 Genomic DNA Translation: AAX66766.1
RefSeqiWP_011264373.1, NC_006905.1

3D structure databases

ProteinModelPortaliQ57KJ6
SMRiQ57KJ6
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAX66766; AAX66766; SCH_2860
KEGGisec:SCH_2860

Phylogenomic databases

KOiK06176
OMAiLWLWVEK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_SALCH
AccessioniPrimary (citable) accession number: Q57KJ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: May 10, 2005
Last modified: November 7, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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