UniProtKB - Q57887 (IF1A_METJA)
Protein
Translation initiation factor 1A
Gene
eIF1A
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Functioni
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).By similarity
GO - Molecular functioni
- translation initiation factor activity Source: UniProtKB-UniRule
Keywordsi
Molecular function | Initiation factor |
Biological process | Protein biosynthesis |
Enzyme and pathway databases
BioCyci | MJAN243232:G1GKE-475-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Translation initiation factor 1AShort name: aIF-1A |
Gene namesi | Name:eIF1A Ordered Locus Names:MJ0445 |
Organismi | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) |
Taxonomic identifieri | 243232 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Methanomada group › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000145121 | 1 – 102 | Translation initiation factor 1AAdd BLAST | 102 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q57887 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q57887 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 85 | S1-likeAdd BLAST | 76 |
Sequence similaritiesi
Belongs to the eIF-1A family.Curated
Phylogenomic databases
eggNOGi | arCOG01179, Archaea |
HOGENOMi | CLU_109098_1_2_2 |
InParanoidi | Q57887 |
OMAi | WRYTRTE |
OrthoDBi | 102432at2157 |
PhylomeDBi | Q57887 |
Family and domain databases
HAMAPi | MF_00216, aIF_1A, 1 hit |
InterProi | View protein in InterPro IPR012340, NA-bd_OB-fold IPR006196, RNA-binding_domain_S1_IF1 IPR001253, TIF_eIF-1A IPR018104, TIF_eIF-1A_CS |
PANTHERi | PTHR21668, PTHR21668, 1 hit |
Pfami | View protein in Pfam PF01176, eIF-1a, 1 hit |
SMARTi | View protein in SMART SM00652, eIF1a, 1 hit |
SUPFAMi | SSF50249, SSF50249, 1 hit |
TIGRFAMsi | TIGR00523, eIF-1A, 1 hit |
PROSITEi | View protein in PROSITE PS01262, IF1A, 1 hit PS50832, S1_IF1_TYPE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q57887-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEQQQEQQI RVRIPRKEEN EILGIIEQML GASRVRVRCL DGKTRLGRIP
60 70 80 90 100
GRLKNRIWVR EGDVVIVKPW EVQGDQKCDI IWRYTKTQVE WLKRKGYLDE
LL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L77117 Genomic DNA Translation: AAB98435.1 |
PIRi | E64355 |
RefSeqi | WP_010869944.1, NC_000909.1 |
Genome annotation databases
EnsemblBacteriai | AAB98435; AAB98435; MJ_0445 |
GeneIDi | 1451305 |
KEGGi | mja:MJ_0445 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L77117 Genomic DNA Translation: AAB98435.1 |
PIRi | E64355 |
RefSeqi | WP_010869944.1, NC_000909.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1JT8 | NMR | - | A | 1-102 | [»] | |
SMRi | Q57887 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 243232.MJ_0445 |
Genome annotation databases
EnsemblBacteriai | AAB98435; AAB98435; MJ_0445 |
GeneIDi | 1451305 |
KEGGi | mja:MJ_0445 |
Phylogenomic databases
eggNOGi | arCOG01179, Archaea |
HOGENOMi | CLU_109098_1_2_2 |
InParanoidi | Q57887 |
OMAi | WRYTRTE |
OrthoDBi | 102432at2157 |
PhylomeDBi | Q57887 |
Enzyme and pathway databases
BioCyci | MJAN243232:G1GKE-475-MONOMER |
Miscellaneous databases
EvolutionaryTracei | Q57887 |
Family and domain databases
HAMAPi | MF_00216, aIF_1A, 1 hit |
InterProi | View protein in InterPro IPR012340, NA-bd_OB-fold IPR006196, RNA-binding_domain_S1_IF1 IPR001253, TIF_eIF-1A IPR018104, TIF_eIF-1A_CS |
PANTHERi | PTHR21668, PTHR21668, 1 hit |
Pfami | View protein in Pfam PF01176, eIF-1a, 1 hit |
SMARTi | View protein in SMART SM00652, eIF1a, 1 hit |
SUPFAMi | SSF50249, SSF50249, 1 hit |
TIGRFAMsi | TIGR00523, eIF-1A, 1 hit |
PROSITEi | View protein in PROSITE PS01262, IF1A, 1 hit PS50832, S1_IF1_TYPE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | IF1A_METJA | |
Accessioni | Q57887Primary (citable) accession number: Q57887 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1996 | |
Last modified: | April 7, 2021 | |
This is version 120 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Translation initiation factors
List of translation initiation factor entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families