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Entry version 131 (02 Jun 2021)
Sequence version 1 (01 Nov 1996)
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Protein
Submitted name:

Capsule biosynthesis protein

Gene

synC

Organism
Neisseria meningitidis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Capsule biosynthesis proteinImported
Submitted name:
Polyhydroxyalkanoate biosynthesis repressor PhaRImported
Submitted name:
Polysialic acid capsule biosynthesis protein SiaCImported
Submitted name:
SiaCImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:synCImported
Synonyms:siaCImported
ORF Names:A6J53_03590Imported, B1A92_03300Imported, CNQ34_04405Imported, ERS514410_00918Imported, GQF23_09070Imported, H7969_09930Imported, NCTC8249_00031Imported, NCTC8554_01562Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNeisseria meningitidisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri487 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000515815 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000188423 Componenti: Unassembled WGS sequence
  • UP000072239 Componenti: Unassembled WGS sequence
  • UP000191237 Componenti: Chromosome
  • UP000217930 Componenti: Unassembled WGS sequence
  • UP000254176 Componenti: Unassembled WGS sequence
  • UP000250161 Componenti: Unassembled WGS sequence
  • UP000471390 Componenti: Unassembled WGS sequence

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB03499, D-Malic acid
DB02787, N-Acetylmannosaminitol
DB01819, Phosphoenolpyruvate

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini292 – 349AFP-likeInterPro annotationAdd BLAST58

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.70, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006190, AFP_Neu5c_C
IPR036732, AFP_Neu5c_C_sf
IPR013785, Aldolase_TIM
IPR013132, Neu5Ac_N
IPR013974, SAF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03102, NeuB, 1 hit
PF08666, SAF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00858, SAF, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51269, SSF51269, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50844, AFP_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q57265-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQNNNEFKIG NRSVGYNHEP LIICEIGINH EGSLKTAFEM VDAAYNAGAE
60 70 80 90 100
VVKHQTHIVE DEMSDEAKQV IPGNADVSIY EIMERCALNE EDEIKLKEYV
110 120 130 140 150
ESKGMIFIST PFSRAAALRL QRMDIPAYKI GSGECNNYPL IKLVASFGKP
160 170 180 190 200
IILSTGMNSI ESIKKSVEII REAGVPYALL HCTNIYPTPY EDVRLGGMND
210 220 230 240 250
LSEAFPDAII GLSDHTLDNY ACLGAVALGG SILERHFTDR MDRPGPDIVC
260 270 280 290 300
SMNPDTFKEL KQGAHALKLA RGGKKDTIIA GEKPTKDFAF ASVVADKDIK
310 320 330 340
KGELLSGDNL WVKRPGNGDF SVNEYETLFG KVAACNIRKG AQIKKTDIE
Length:349
Mass (Da):38,348
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1C7C13EE5847E71A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M95053 Genomic DNA Translation: AAA20477.1
U40740 Genomic DNA Translation: AAB17455.1
HM037270 Genomic DNA Translation: ADK90955.1
CP020401 Genomic DNA Translation: ARB68610.1
FESW01000010 Genomic DNA Translation: CWO11850.1
WSOB01000046 Genomic DNA Translation: MVZ59992.1
MVCA01000010 Genomic DNA Translation: OOG98479.1
NTLY01000002 Genomic DNA Translation: PBJ87223.1
CP060280 Genomic DNA Translation: QNK91477.1
UATD01000002 Genomic DNA Translation: SPY01716.1
UGRP01000001 Genomic DNA Translation: SUA19834.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S60760

NCBI Reference Sequences

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RefSeqi
WP_002215299.1, NZ_WSOH01000068.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CWO11850; CWO11850; ERS514410_00918
OOG98479; OOG98479; B1A92_03300
PBJ87223; PBJ87223; CNQ34_04405
SPY01716; SPY01716; NCTC8249_00031
SUA19834; SUA19834; NCTC8554_01562

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|487.1145.peg.71

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M95053 Genomic DNA Translation: AAA20477.1
U40740 Genomic DNA Translation: AAB17455.1
HM037270 Genomic DNA Translation: ADK90955.1
CP020401 Genomic DNA Translation: ARB68610.1
FESW01000010 Genomic DNA Translation: CWO11850.1
WSOB01000046 Genomic DNA Translation: MVZ59992.1
MVCA01000010 Genomic DNA Translation: OOG98479.1
NTLY01000002 Genomic DNA Translation: PBJ87223.1
CP060280 Genomic DNA Translation: QNK91477.1
UATD01000002 Genomic DNA Translation: SPY01716.1
UGRP01000001 Genomic DNA Translation: SUA19834.1
PIRiS60760
RefSeqiWP_002215299.1, NZ_WSOH01000068.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XUUX-ray1.90A1-349[»]
1XUZX-ray2.20A1-349[»]
4IPIX-ray1.75A1-349[»]
4IPJX-ray2.15A1-349[»]
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...
PDBe-KBiSearch...

Chemistry databases

DrugBankiDB03499, D-Malic acid
DB02787, N-Acetylmannosaminitol
DB01819, Phosphoenolpyruvate

Genome annotation databases

EnsemblBacteriaiCWO11850; CWO11850; ERS514410_00918
OOG98479; OOG98479; B1A92_03300
PBJ87223; PBJ87223; CNQ34_04405
SPY01716; SPY01716; NCTC8249_00031
SUA19834; SUA19834; NCTC8554_01562
PATRICifig|487.1145.peg.71

Family and domain databases

Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR006190, AFP_Neu5c_C
IPR036732, AFP_Neu5c_C_sf
IPR013785, Aldolase_TIM
IPR013132, Neu5Ac_N
IPR013974, SAF
PfamiView protein in Pfam
PF03102, NeuB, 1 hit
PF08666, SAF, 1 hit
SMARTiView protein in SMART
SM00858, SAF, 1 hit
SUPFAMiSSF51269, SSF51269, 1 hit
PROSITEiView protein in PROSITE
PS50844, AFP_LIKE, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ57265_NEIME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q57265
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 2, 2021
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

3D-structureCombined sources
UniProt is an ELIXIR core data resource
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