UniProtKB - Q570Y9 (DPTOR_MOUSE)

BLAST

>sp|Q570Y9|DPTOR_MOUSE DEP domain-containing mTOR-interacting protein OS=Mus musculus OX=10090 GN=Deptor PE=1 SV=2
MEEGSSGGSGSSDSNAGGSGGVQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTY
PNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKD
DGTFALDSEVKAFMRGQRLYEKLMSPETTLLQPREEEGVKYERTFMASEFLDWLVQEGEA
TTRKEAEQLCHRLMDHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLNETSPSSQE
THDSPFCLRKQSHDSRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSP
PVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGP
AAAAGMKVCQFVVSVNGLNVLNVDYRTVSNLILTGPRTIVMEVMEELDC

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History
Entry version 101 (07 Nov 2018)
Sequence version 2 (17 Apr 2007)
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Protein

DEP domain-containing mTOR-interacting protein

Gene

Deptor

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes (By similarity).By similarity

GO - Biological processⁱ

intracellular signal transduction Source: InterPro
negative regulation of cell size Source: MGI
negative regulation of protein kinase activity Source: MGI
negative regulation of TOR signaling Source: MGI
regulation of extrinsic apoptotic signaling pathway Source: MGI

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: DEP domain-containing mTOR-interacting protein Alternative name(s): DEP domain-containing protein 6
Gene namesⁱ	Name:Deptor Synonyms:Depdc6, Kiaa4200
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 15

Organism-specific databases

MGIⁱ	MGI:2146322 Deptor

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000284785	1 – 409	DEP domain-containing mTOR-interacting proteinAdd BLAST		409

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	1	N-acetylmethionineBy similarity	1
Modified residueⁱ	241	PhosphothreonineBy similarity	1
Modified residueⁱ	244	PhosphoserineCombined sources	1
Modified residueⁱ	258	PhosphoserineBy similarity	1
Modified residueⁱ	259	PhosphothreonineBy similarity	1
Modified residueⁱ	263	PhosphoserineBy similarity	1
Modified residueⁱ	265	PhosphoserineCombined sources	1
Modified residueⁱ	280	PhosphoserineCombined sources	1
Modified residueⁱ	282	PhosphoserineBy similarity	1
Modified residueⁱ	283	PhosphoserineBy similarity	1
Modified residueⁱ	287	PhosphoserineBy similarity	1
Modified residueⁱ	293	PhosphoserineCombined sources	1
Modified residueⁱ	297	PhosphoserineBy similarity	1
Modified residueⁱ	298	PhosphoserineBy similarity	1
Modified residueⁱ	299	PhosphoserineBy similarity	1

Post-translational modificationⁱ

Phosphorylation weakens interaction with MTOR within mTORC1 and mTORC2.By similarity

Ubiquitinated; ubiquitination leads to proteasomal degradation.By similarity

Keywords - PTMⁱ

Acetylation, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbⁱ	Q570Y9
PRIDEⁱ	Q570Y9

PTM databases

iPTMnetⁱ	Q570Y9
PhosphoSitePlusⁱ	Q570Y9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000022419 Expressed in 254 organ(s), highest expression level in brown adipose tissue
CleanExⁱ	MM_DEPDC6
ExpressionAtlasⁱ	Q570Y9 baseline and differential
Genevisibleⁱ	Q570Y9 MM

Interactionⁱ

Subunit structureⁱ

Part of the mammalian target of rapamycin complex 1 (mTORC1) which contains MTOR, MLST8, RPTOR, AKT1S1/PRAS40 and DEPTOR. Part of the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PROTOR1, RICTOR, MAPKAP1 and DEPTOR. Interacts (via PDZ domain) with MTOR; interacts with MTOR within both mammalian target of rapamycin complexes mTORC1 and mTORC2 (By similarity). Interacts (via PDZ domain) with MINAR1 (via N-terminus) (By similarity).By similarity

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000094167

STRINGⁱ

10090.ENSMUSP00000094167

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q570Y9
SMRⁱ	Q570Y9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	36 – 119	DEP 1PROSITE-ProRule annotationAdd BLAST	84
Domainⁱ	146 – 219	DEP 2PROSITE-ProRule annotationAdd BLAST	74
Domainⁱ	330 – 407	PDZPROSITE-ProRule annotationAdd BLAST	78

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	235 – 299	Ser-richAdd BLAST		65

Keywords - Domainⁱ

Repeat

Phylogenomic databases

eggNOGⁱ	ENOG410IKSC Eukaryota ENOG4110T1J LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00520000055667
HOVERGENⁱ	HBG056008
InParanoidⁱ	Q570Y9
KEGG Orthology (KO) More...KOⁱ	K20402
OMAⁱ	AHDSPFC
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AB3
PhylomeDBⁱ	Q570Y9

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd04442 DEP_1_DEP6, 1 hit cd04441 DEP_2_DEP6, 1 hit
Gene3Dⁱ	1.10.10.10, 2 hits
InterProⁱ	View protein in InterPro IPR000591 DEP_dom IPR037589 DEPTOR IPR037335 DEPTOR_DEP_1 IPR037336 DEPTOR_DEP_2 IPR001478 PDZ IPR036034 PDZ_sf IPR036388 WH-like_DNA-bd_sf IPR036390 WH_DNA-bd_sf
PANTHERⁱ	PTHR22829:SF18 PTHR22829:SF18, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00610 DEP, 2 hits
SMARTⁱ	View protein in SMART SM00049 DEP, 2 hits SM00228 PDZ, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 2 hits SSF50156 SSF50156, 1 hit
PROSITEⁱ	View protein in PROSITE PS50186 DEP, 2 hits PS50106 PDZ, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q570Y9-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEEGSSGGSG SSDSNAGGSG GVQQRELERM AEVLVTGEQL RLRLHEEKVI 
        60         70         80         90        100
KDRRHHLKTY PNCFVAKELI DWLIEHKEAS DRETAIKLMQ KLADRGIIHH 
       110        120        130        140        150
VCDEHKEFKD VKLFYRFRKD DGTFALDSEV KAFMRGQRLY EKLMSPETTL 
       160        170        180        190        200
LQPREEEGVK YERTFMASEF LDWLVQEGEA TTRKEAEQLC HRLMDHGIIQ 
       210        220        230        240        250
HVSNKHPFVD SNLLYQFRMN FRRRRRLMEL LNETSPSSQE THDSPFCLRK 
       260        270        280        290        300
QSHDSRKSTS FMSVSPSKEI KIVSAVRRSS MSSCGSSGYF SSSPTLSSSP 
       310        320        330        340        350
PVLCNPKSVL KRPVTSEELL TPGAPYARKT FTIVGDAVGW GFVVRGSKPC 
       360        370        380        390        400
HIQAVDPSGP AAAAGMKVCQ FVVSVNGLNV LNVDYRTVSN LILTGPRTIV 

MEVMEELDC

Length:409

Mass (Da):46,120

Last modified:April 17, 2007 - v2

Checksum:ⁱ072062418DADDF8E

Isoform 2 (identifier: Q570Y9-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-40: MEEGSSGGSGSSDSNAGGSGGVQQRELERMAEVLVTGEQL → MKQAFLVVLRHSISEDRLPPLSVITSGC

« Hide

        10         20         30         40         50
MKQAFLVVLR HSISEDRLPP LSVITSGCRL RLHEEKVIKD RRHHLKTYPN 
        60         70         80         90        100
CFVAKELIDW LIEHKEASDR ETAIKLMQKL ADRGIIHHVC DEHKEFKDVK 
       110        120        130        140        150
LFYRFRKDDG TFALDSEVKA FMRGQRLYEK LMSPETTLLQ PREEEGVKYE 
       160        170        180        190        200
RTFMASEFLD WLVQEGEATT RKEAEQLCHR LMDHGIIQHV SNKHPFVDSN 
       210        220        230        240        250
LLYQFRMNFR RRRRLMELLN ETSPSSQETH DSPFCLRKQS HDSRKSTSFM 
       260        270        280        290        300
SVSPSKEIKI VSAVRRSSMS SCGSSGYFSS SPTLSSSPPV LCNPKSVLKR 
       310        320        330        340        350
PVTSEELLTP GAPYARKTFT IVGDAVGWGF VVRGSKPCHI QAVDPSGPAA 
       360        370        380        390 
AAGMKVCQFV VSVNGLNVLN VDYRTVSNLI LTGPRTIVME VMEELDC

Note: No experimental confirmation available.

Show »

Length:397

Mass (Da):45,233

Checksum:ⁱ2F65AF24F475B601

Isoform 3 (identifier: Q570Y9-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
368-409: VCQFVVSVNG...VMEVMEELDC → DTGTESRKIVTSRLAWATWQDLMGGKVGGDAIPI

« Hide

        10         20         30         40         50
MEEGSSGGSG SSDSNAGGSG GVQQRELERM AEVLVTGEQL RLRLHEEKVI 
        60         70         80         90        100
KDRRHHLKTY PNCFVAKELI DWLIEHKEAS DRETAIKLMQ KLADRGIIHH 
       110        120        130        140        150
VCDEHKEFKD VKLFYRFRKD DGTFALDSEV KAFMRGQRLY EKLMSPETTL 
       160        170        180        190        200
LQPREEEGVK YERTFMASEF LDWLVQEGEA TTRKEAEQLC HRLMDHGIIQ 
       210        220        230        240        250
HVSNKHPFVD SNLLYQFRMN FRRRRRLMEL LNETSPSSQE THDSPFCLRK 
       260        270        280        290        300
QSHDSRKSTS FMSVSPSKEI KIVSAVRRSS MSSCGSSGYF SSSPTLSSSP 
       310        320        330        340        350
PVLCNPKSVL KRPVTSEELL TPGAPYARKT FTIVGDAVGW GFVVRGSKPC 
       360        370        380        390        400
HIQAVDPSGP AAAAGMKDTG TESRKIVTSR LAWATWQDLM GGKVGGDAIP 

I

Note: No experimental confirmation available.

Show »

Length:401

Mass (Da):45,066

Checksum:ⁱE502ECF5C3615B97

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

B2ZRS5	B2ZRS5_MOUSE	DEP domain-containing mTOR-interact... DEP domain-containing mTOR-interacting protein (Depdc6-002)	Deptor Depdc6	401	Annotation score:
A0A2I3BRE1	A0A2I3BRE1_MOUSE	DEP domain-containing mTOR-interact... DEP domain-containing mTOR-interacting protein	Deptor	100	Annotation score:

Sequence cautionⁱ

The sequence BAD90225 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	11	S → G in BAE26298 (PubMed:16141072).Curated	1
Sequence conflictⁱ	125	A → P in BAE26298 (PubMed:16141072).Curated	1
Sequence conflictⁱ	128	S → N in BAE26298 (PubMed:16141072).Curated	1
Sequence conflictⁱ	149	T → I in BAE26298 (PubMed:16141072).Curated	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_024648	1 – 40	MEEGS…TGEQL → MKQAFLVVLRHSISEDRLPP LSVITSGC in isoform 2. 1 PublicationAdd BLAST		40
Alternative sequenceⁱVSP_024649	368 – 409	VCQFV…EELDC → DTGTESRKIVTSRLAWATWQ DLMGGKVGGDAIPI in isoform 3. 1 PublicationAdd BLAST		42

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK220300 mRNA Translation: BAD90225.1 Different initiation. AK139888 mRNA Translation: BAE24172.1 AK145208 mRNA Translation: BAE26298.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS27474.1 [Q570Y9-1] CCDS27475.1 [Q570Y9-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001033026.1, NM_001037937.3 [Q570Y9-2] NP_663445.2, NM_145470.3 [Q570Y9-1]
UniGeneⁱ	Mm.295397 Mm.393497

Genome annotation databases

Ensemblⁱ	ENSMUST00000023056; ENSMUSP00000023056; ENSMUSG00000022419 [Q570Y9-2] ENSMUST00000096433; ENSMUSP00000094167; ENSMUSG00000022419 [Q570Y9-1]
GeneIDⁱ	97998
KEGGⁱ	mmu:97998
UCSC genome browser More...UCSCⁱ	uc007vsb.2 mouse [Q570Y9-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Protein	Similar proteins		Species	Score	Length	Source
Q570Y9	Depdc6-001		MOUSE		409	UniRef100_Q570Y9
Q570Y9-2	Depdc6-003		MOUSE		397	UniRef100_B2ZRS7

Protein	Similar proteins		Species	Score	Length	Source
Q570Y9	DEP domain-containing mTOR-interacting protein		HUMAN		409	UniRef90_Q8TB45
DEP domain-containing mTOR-interacting protein		PANTR		409
Uncharacterized protein		PANPA		409
DEP domain containing MTOR interacting protein		GORGO		409
Uncharacterized protein		RABIT		498
+96
Q570Y9-2	DEP domain containing MTOR interacting protein		BOVIN		365	UniRef90_F6RLE1
Uncharacterized protein		MACNE		454
Uncharacterized protein		MONDO		420
Uncharacterized protein		MACFA		398
Depdc6-003		MOUSE		397
+36
Q570Y9-3	DEP domain-containing mTOR-interacting protein		MOUSE		401	UniRef90_Q570Y9-3
UPI000948198E		AILME		338
Depdc6-002		MOUSE		401

Protein	Similar proteins		Species	Score	Length	Source
Q570Y9	DEP domain-containing mTOR-interacting protein		HUMAN		409	UniRef50_Q8TB45
DEP domain-containing mTOR-interacting protein		PANTR		409
Uncharacterized protein		PANPA		409
DEP domain containing MTOR interacting protein		GORGO		409
Uncharacterized protein		RABIT		498
+265
Q570Y9-3	DEP domain-containing mTOR-interacting protein		MOUSE		401	UniRef50_Q570Y9-3
DEP domain-containing MTOR-interacting protein		XENTR		369
Uncharacterized protein		XENLA		396
DEP domain-containing mTOR-interacting protein isoform X1		ICTPU		396
DEP domain-containing MTOR-interacting protein		DANRE		407
+387

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK220300 mRNA Translation: BAD90225.1 Different initiation. AK139888 mRNA Translation: BAE24172.1 AK145208 mRNA Translation: BAE26298.1
CCDSⁱ	CCDS27474.1 [Q570Y9-1] CCDS27475.1 [Q570Y9-2]
RefSeqⁱ	NP_001033026.1, NM_001037937.3 [Q570Y9-2] NP_663445.2, NM_145470.3 [Q570Y9-1]
UniGeneⁱ	Mm.295397 Mm.393497

3D structure databases

ProteinModelPortalⁱ	Q570Y9
SMRⁱ	Q570Y9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000094167

STRINGⁱ

10090.ENSMUSP00000094167

PTM databases

iPTMnetⁱ	Q570Y9
PhosphoSitePlusⁱ	Q570Y9

Proteomic databases

PaxDbⁱ	Q570Y9
PRIDEⁱ	Q570Y9

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	97998
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000023056; ENSMUSP00000023056; ENSMUSG00000022419 [Q570Y9-2] ENSMUST00000096433; ENSMUSP00000094167; ENSMUSG00000022419 [Q570Y9-1]
GeneIDⁱ	97998
KEGGⁱ	mmu:97998
UCSCⁱ	uc007vsb.2 mouse [Q570Y9-1]

Organism-specific databases

CTDⁱ	64798
MGIⁱ	MGI:2146322 Deptor
Rougeⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IKSC Eukaryota ENOG4110T1J LUCA
GeneTreeⁱ	ENSGT00520000055667
HOVERGENⁱ	HBG056008
InParanoidⁱ	Q570Y9
KOⁱ	K20402
OMAⁱ	AHDSPFC
OrthoDBⁱ	EOG091G0AB3
PhylomeDBⁱ	Q570Y9

Miscellaneous databases

ChiTaRSⁱ	Deptor mouse
Protein Ontology More...PROⁱ	PR:Q570Y9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000022419 Expressed in 254 organ(s), highest expression level in brown adipose tissue
CleanExⁱ	MM_DEPDC6
ExpressionAtlasⁱ	Q570Y9 baseline and differential
Genevisibleⁱ	Q570Y9 MM

Family and domain databases

CDDⁱ	cd04442 DEP_1_DEP6, 1 hit cd04441 DEP_2_DEP6, 1 hit
Gene3Dⁱ	1.10.10.10, 2 hits
InterProⁱ	View protein in InterPro IPR000591 DEP_dom IPR037589 DEPTOR IPR037335 DEPTOR_DEP_1 IPR037336 DEPTOR_DEP_2 IPR001478 PDZ IPR036034 PDZ_sf IPR036388 WH-like_DNA-bd_sf IPR036390 WH_DNA-bd_sf
PANTHERⁱ	PTHR22829:SF18 PTHR22829:SF18, 1 hit
Pfamⁱ	View protein in Pfam PF00610 DEP, 2 hits
SMARTⁱ	View protein in SMART SM00049 DEP, 2 hits SM00228 PDZ, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 2 hits SSF50156 SSF50156, 1 hit
PROSITEⁱ	View protein in PROSITE PS50186 DEP, 2 hits PS50106 PDZ, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	DPTOR_MOUSE
Accessionⁱ	Q570Y9Primary (citable) accession number: Q570Y9 Secondary accession number(s): Q3UM00, Q3UT08
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 17, 2007
	Last sequence update:	April 17, 2007
	Last modified:	November 7, 2018
	This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q570Y9 (DPTOR_MOUSE)

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DEP domain-containing mTOR-interacting protein

Deptor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Compositional bias

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ