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  1. 1
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Lymph.
    Source: UniProtKB/TrEMBL (unreviewed).

    This publication is cited by 50448 other entries.

  2. 2
    Category: Function, Pathology & Biotech.
    Annotation: Not Associated with CANCER: breast cancer. [GAD:131491]. Observational study of gene-disease association. (HuGE Navigator). [GeneRIF:8202].
    Source: GAD:131491, GeneRIF:8202.

    This publication is mapped to 7 other entries.

  3. 3
    "Alleles of the estrogen receptor alpha-gene and an estrogen receptor cotranscriptional activator gene, amplified in breast cancer-1 (AIB1), are associated with quantitative calcaneal ultrasound."
    Patel M.S., Cole D.E., Smith J.D., Hawker G.A., Wong B., Trang H., Vieth R., Meltzer P., Rubin L.A.
    J. Bone Miner. Res. 15:2231-2239(2000) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech, Sequences.
    Annotation: Associated with OTHER: quantitative calcaneal ultrasound. [GAD:131487]. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator). [GeneRIF:8202].
    Source: GAD:131487, GeneRIF:8202.

    This publication is mapped to 89 other entries.

  4. 4
    "Genetic factors related to racial variation in plasma levels of insulin-like growth factor-1: implications for premenopausal breast cancer risk."
    Jernstrom H., Chu W., Vesprini D., Tao Y., Majeed N., Deal C., Pollak M., Narod S.A.
    Mol. Genet. Metab. 72:144-154(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:8202.

    This publication is mapped to 19 other entries.

  5. 5
    "Polymorphic CAG/CAA repeat length in the AIB1/SRC-3 gene and prostate cancer risk: a population-based case-control study."
    Hsing A.W., Chokkalingam A.P., Gao Y.T., Wu G., Wang X., Deng J., Cheng J., Sesterhenn I.A., Mostofi F.K., Chiang T., Chen Y.L., Stanczyk F.Z., Chang C.
    Cancer Epidemiol. Biomarkers Prev. 11:337-341(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); CAG/CAA repeat length in AIB1/SRC-3 gene may be associated with prosate cancer risk in Chinese men.
    Source: GeneRIF:8202.

    This publication is mapped to 26 other entries.

  6. 6
    "Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways."
    Dong S., Tweardy D.J.
    Blood 99:2637-2646(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: the effect of STAT5b-RARalpha on the activity of myeloid transcription factors including STAT3 and STAT5 as well as its molecular interactions with the nuclear receptor corepressor SMRT and nuclear receptor coactivator TRAM-1.
    Source: GeneRIF:8202.

    This publication is mapped to 29 other entries.

  7. 7
    "Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) coactivator activity by I kappa B kinase."
    Wu R.-C., Qin J., Hashimoto Y., Wong J., Xu J., Tsai S.Y., Tsai M.-J., O'Malley B.W.
    Mol. Cell. Biol. 22:3549-3561(2002) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: Results show that IKK-mediated phosphorylation of SRC-3 is a regulated event that plays an important role and also substantiate the role of SRC-3 in multiple signaling pathways.
    Source: GeneRIF:8202.

    This publication is cited by 5 and mapped to 8 other entries.

  8. 8
    "Polymorphisms in steroid hormone pathway genes and mammographic density."
    Haiman C.A., Hankinson S.E., De Vivo I., Guillemette C., Ishibe N., Hunter D.J., Byrne C.
    Breast Cancer Res. Treat. 77:27-36(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:8202.

    This publication is mapped to 99 other entries.

  9. 9
    "Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1."
    Liao L., Kuang S.Q., Yuan Y., Gonzalez S.M., O'Malley B.W., Xu J.
    J. Steroid Biochem. Mol. Biol. 83:3-14(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: SRC-3 has a role in the vasoprotective effects of estrogen and in cell migration proliferation and cancers (review).
    Source: GeneRIF:8202.

    This publication is mapped to 14 other entries.

  10. 10
    "Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis."
    Zhao C., Yasui K., Lee C.J., Kurioka H., Hosokawa Y., Oka T., Inazawa J.
    Cancer 98:18-23(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: likely prognostic indicator for patients with breast tumors.
    Source: GeneRIF:8202.

    This publication is mapped to 13 other entries.

  11. 11
    "Clinical significance of AIB1 expression in human breast cancer."
    Iwase H., Omoto Y., Toyama T., Yamashita H., Hara Y., Sugiura H., Zhang Z.
    Breast Cancer Res. Treat. 80:339-345(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: AIB1 nuclear expression correlated with estrogen receptor alpha status in breast cancer; patients with AIB1 nuclear expression tended to be successfully treated by hormonal therapy.
    Source: GeneRIF:8202.

    This publication is mapped to 7 other entries.

  12. 12
    "Correlates of obesity in postmenopausal women with breast cancer: comparison of genetic, demographic, disease-related, life history and dietary factors."
    Wasserman L., Flatt S.W., Natarajan L., Laughlin G., Matusalem M., Faerber S., Rock C.L., Barrett-Connor E., Pierce J.P.
    Int. J. Obes. Relat. Metab. Disord. 28:49-56(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator).
    Source: GeneRIF:8202.

    This publication is mapped to 14 other entries.

  13. 13
    "Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers."
    Kadouri L., Kote-Jarai Z., Easton D.F., Hubert A., Hamoudi R., Glaser B., Abeliovich D., Peretz T., Eeles R.A.
    Int. J. Cancer 108:399-403(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers.
    Source: GeneRIF:8202.

    This publication is mapped to 7 other entries.

  14. 14
    "Somatic instability of the DNA sequences encoding the polymorphic polyglutamine tract of the AIB1 gene."
    Dai P., Wong L.J.
    J. Med. Genet. 40:885-890(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: The polymorphic polyglutamine tract of the AIB1 gene is somatically unstable in breast cancer tissue and cell lines.
    Source: GeneRIF:8202.

    This publication is mapped to 7 other entries.

  15. 15
    "Impact of the nuclear receptor coactivator AIB1 isoform AIB1-Delta3 on estrogenic ligands with different intrinsic activity."
    Reiter R., Oh A.S., Wellstein A., Riegel A.T.
    Oncogene 23:403-409(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: AIB1-Delta3 causes a significant increase in the efficacy of 17beta-estradiol at both estrogen receptor-alpha (ER-alpha) and ER-beta in ovarian breast and endometrial cancer cell lines.
    Source: GeneRIF:8202.

    This publication is mapped to 89 other entries.

  16. 16
    "Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu."
    Goel A., Janknecht R.
    J. Biol. Chem. 279:14909-14916(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: HER2/Neu and ACTR may synergize to orchestrate mammary tumorigenesis through the dysregulation of the transcription factor ER81 and its target genes.
    Source: GeneRIF:8202.

    This publication is mapped to 28 other entries.

  17. 17
    "ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance."
    Louie M.C., Zou J.X., Rabinovich A., Chen H.W.
    Mol. Cell. Biol. 24:5157-5171(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: results reveal an essential role of ACTR in control of breast cancer cell proliferation and implicate the ACTR-E2F1 pathway as a novel mechanism in antiestrogen resistance.
    Source: GeneRIF:8202.

    This publication is mapped to 9 other entries.

  18. 18
    "Coactivator AIB1 links estrogen receptor transcriptional activity and stability."
    Shao W., Keeton E.K., McDonnell D.P., Brown M.
    Proc. Natl. Acad. Sci. U.S.A. 101:11599-11604(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: AIB1 plays a dual role in regulating ERalpha activity one in recruiting transcription factors including other coactivators involved in gene activation and the other in regulating ERalpha protein degradation mediated by the ubiquitin-proteosome machinery.
    Source: GeneRIF:8202.

    This publication is mapped to 89 other entries.

  19. 19
    "Overexpression of the nuclear receptor coactivator AIB1 (SRC-3) during progression of pancreatic adenocarcinoma."
    Henke R.T., Haddad B.R., Kim S.E., Rone J.D., Mani A., Jessup J.M., Wellstein A., Maitra A., Riegel A.T.
    Clin. Cancer Res. 10:6134-6142(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: AIB1 has a major role in the multistage progression of pancreatic cancer.
    Source: GeneRIF:8202.

    This publication is mapped to 7 other entries.

  20. 20
    "The nuclear receptor coactivator AIB1 mediates insulin-like growth factor I-induced phenotypic changes in human breast cancer cells."
    Oh A., List H.J., Reiter R., Mani A., Zhang Y., Gehan E., Wellstein A., Riegel A.T.
    Cancer Res. 64:8299-8308(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: AIB1 is required for IGF-I-induced proliferation signaling cell survival and gene expression in human breast cancer cells independent of its role in estrogen receptor signaling.
    Source: GeneRIF:8202.

    This publication is mapped to 14 other entries.

  21. 21
    "Overexpression of an N-terminally truncated isoform of the nuclear receptor coactivator amplified in breast cancer 1 leads to altered proliferation of mammary epithelial cells in transgenic mice."
    Tilli M.T., Reiter R., Oh A.S., Henke R.T., McDonnell K., Gallicano G.I., Furth P.A., Riegel A.T.
    Mol. Endocrinol. 19:644-656(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: the N-terminally deleted isoform of AIB1 can play a role in breast cancer development and/or progression.
    Source: GeneRIF:8202.

    This publication is mapped to 14 other entries.

  22. 22
    "Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator."
    Labhart P., Karmakar S., Salicru E.M., Egan B.S., Alexiadis V., O'Malley B.W., Smith C.L.
    Proc. Natl. Acad. Sci. U.S.A. 102:1339-1344(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: The ability of SRC family coactivators to regulate the expression of one of these genes PARD6B/Par6 was confirmed by using cells individually depleted of SRC-1.
    Source: GeneRIF:8202.

    This publication is mapped to 8 other entries.

  23. 23
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); Single Nucleotide Polymorphisms in NCOA3 is associated with breast cancer risk.
    Source: GeneRIF:8202.

    This publication is mapped to 7 other entries.

  24. 24
    Category: Pathology & Biotech, Sequences.
    Annotation: There is no significant effect of AIB1 genetic variation on breast cancer risk in BRC1 or BRCA2 mutation carriers; Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator).
    Source: GeneRIF:8202.

    This publication is mapped to 132 other entries.

  25. 25
    "The AIB1 glutamine repeat polymorphism is not associated with risk of breast cancer before age 40 years in Australian women."
    Montgomery K.G., Chang J.H., Gertig D.M., Dite G.S., McCredie M.R., Giles G.G., Southey M.C., Hopper J.L., Campbell I.G.
    Breast Cancer Res. 7:R353-6(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Not Associated with CANCER: breast cancer. [GAD:131489]. Observational study of gene-disease association. (HuGE Navigator). [GeneRIF:8202].
    Source: GeneRIF:8202, GAD:131489.

    This publication is mapped to 7 other entries.

1 to 25 of 198  Show
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