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Protein
Submitted name:

HMGXB3 protein

Gene

HMGXB3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi191 – 249HMG boxPROSITE-ProRule annotationAdd BLAST59

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
HMGXB3 proteinImported
Gene namesi
Name:HMGXB3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164720627

PTM / Processingi

Proteomic databases

PeptideAtlasiQ562E5
PRIDEiQ562E5

Expressioni

Gene expression databases

GenevisibleiQ562E5 HS

Interactioni

Protein-protein interaction databases

IntActiQ562E5, 2 interactors

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini191 – 249HMG boxInterPro annotationAdd BLAST59

Phylogenomic databases

eggNOGiENOG410IF99 Eukaryota
ENOG410XVX8 LUCA
HOGENOMiHOG000112914
HOVERGENiHBG061011

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR039598 HMGXB3
PANTHERiPTHR17609 PTHR17609, 1 hit
PfamiView protein in Pfam
PF09011 HMG_box_2, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit

Sequencei

Sequence statusi: Fragment.

Q562E5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
WRSVVCRYCR CSRQTGASVT TVSLPSSSSS PGLDPRGPRQ ASVRSLRSEP
60 70 80 90 100
VLLFLPFRTP YRDSEKGKRE GLSRLRAVCR RAGPRGRGSF SPRDARASPR
110 120 130 140 150
LHFLVAAVTT GAASRRQRGA RVRQPSPSSS RRAKRLRECE RRSLHAPPAM
160 170 180 190 200
DASYDGTEVT VVMEEIEEAY CYTSPGPPKK KKKYKIHGEK TKKPRSAYLL
210 220 230 240 250
YYYDIYLKVQ QELPHLPQSE INKKISESWR LLSVAERSYY LEKAKLEKEG
260 270 280 290 300
LDPNSKLSAL TAVVPDIPGF RKILPRSDYI IIPKSSLQED RSCPQLELCV
310 320 330 340 350
AQNQMSPKGP PLVSNTAPET VPSHAGMAEQ CLAVEALAEE VGALTQSGAV
360 370 380 390 400
QEIATSEILS QDVLLEDASL EVGESHQPYQ TSLVIEETLV NGSPDLPTGS
410 420 430 440 450
LAVPHPQVGE SISVVTVMRD SSESSSSAPA TQFIMLPLPA YSVVENPTSI
460 470 480 490 500
KLTTTYTRRG HGTCTSPGCS FTYVTRHKPP KCPTCGNFLG GKWIPKEKPA
510 520 530 540 550
KVKVELASGV SSKGSVVKRN QQPVTTEQNS SKENASKLTL ENSEAVSQLL
560 570 580 590 600
NVAPPREVGE ESEWEEVIIS DAHVLVKEAP GNCGTAVTKT PVVKSGVQPE
610 620 630 640 650
VTLGTTDNDS PGADVPTPSE GTSTSSPLPA PKKPTGVDLL TPGSRAPELK
660 670 680 690 700
GRARGKPSLL AAARPMRAIL PAPVNVGRGS SMGLPRARQA FSLSDKTPSV
710 720 730 740 750
RTCGLKPSTL KQLGQPIQQP SGPGEVKLPS GPSNRTSQVK VVEVKPDMFP
760 770 780 790 800
PYKYSCTVTL DLGLATSRGR GKCKNPSCSY VYTNRHKPRI CPSCGVNLAK
810 820 830 840 850
DRTEKTTKAI EVSSPLPDVL NATEPLSTAQ REIQRQSTLQ LLRKVLQIPE
860 870 880 890 900
NESELAEVFA LIHELNSSRL ILSNVSEETV TIEQTSWSNY YESPSTQCLL
910 920 930 940 950
CSSPLFKGGQ NSLAGPQECW LLTASRLQTV TAQVKMCLNP HCLALHSFID
960 970 980 990 1000
IYTGLFNVGN KLLVSLDLLF AIRNQIKLGE DPRVSINVVL KSVQEQTEKT
1010 1020 1030 1040 1050
LTSEELSQLQ ELLCNGYWAF ECLTVRDYND MICGICGVAP KVEMAQRSEE
1060 1070 1080 1090 1100
NVLALKSVEF TWPEFLGSNE VNVEDFWATM ETEVIEQVAF PASIPITKFD
1110 1120 1130 1140 1150
ASVIAPFFPP LMRGAVVVNT EKDKNLDVQP VPGSGSALVR LLQEGTCKLD
1160 1170 1180 1190 1200
EIGSYSEEKL QHLLRQCGIP FGAEDSKDQL CFSLLALYES VQNGARAIRP
1210 1220 1230 1240 1250
PRHFTGGKIY KVCPHQVVCG SKYLVRGESA RDHVDLLASS RHWPPVYVVD
1260 1270 1280 1290 1300
MATSVALCAD LCYPELTNQM WGRNQGCFSS PTEPPVSVSC PELLDQHYTV
1310 1320 1330 1340 1350
DMTETEHSIQ HPVTKTATRR IVHAGLQPNP GDPSAGHHSL ALCPELAPYA
1360 1370 1380 1390 1400
TILASIVDSK PNGVRQRPIA FDNATHYYLY NRLMDFLTSR EIVNRQIHDI
1410 1420 1430 1440
VQSCQPGEVV IRDTLYRLGV AQIKTETEEE GEEEEVAAVA E
Length:1,441
Mass (Da):157,653
Last modified:May 10, 2005 - v1
Checksum:i68A1B8307814960B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC092520 mRNA Translation: AAH92520.1
RefSeqiNP_055798.2, NM_014983.2
UniGeneiHs.719189

Genome annotation databases

GeneIDi22993
KEGGihsa:22993

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC092520 mRNA Translation: AAH92520.1
RefSeqiNP_055798.2, NM_014983.2
UniGeneiHs.719189

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ562E5, 2 interactors

Proteomic databases

PeptideAtlasiQ562E5
PRIDEiQ562E5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi22993
KEGGihsa:22993

Organism-specific databases

CTDi22993
PharmGKBiPA164720627

Phylogenomic databases

eggNOGiENOG410IF99 Eukaryota
ENOG410XVX8 LUCA
HOGENOMiHOG000112914
HOVERGENiHBG061011

Miscellaneous databases

ChiTaRSiHMGXB3 human
GenomeRNAii22993

Gene expression databases

GenevisibleiQ562E5 HS

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR039598 HMGXB3
PANTHERiPTHR17609 PTHR17609, 1 hit
PfamiView protein in Pfam
PF09011 HMG_box_2, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ562E5_HUMAN
AccessioniPrimary (citable) accession number: Q562E5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 7, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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