Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serine/threonine-protein kinase dst2

Gene

dst2

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.By similarity

Cofactori

Mg2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei49ATPPROSITE-ProRule annotationBy similarity1
Active sitei141Proton acceptorPROSITE-ProRule annotationBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi26 – 34ATPPROSITE-ProRule annotationBy similarity9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase dst2By similarity (EC:2.7.11.1)
Gene namesi
Name:dst2Imported
Synonyms:dstB1 Publication
ORF Names:DDB_G0267730
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0267730 dst2

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003555801 – 1142Serine/threonine-protein kinase dst2Add BLAST1142

Proteomic databases

PaxDbiQ55GC2

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0216378

Structurei

3D structure databases

ProteinModelPortaliQ55GC2
SMRiQ55GC2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 276Protein kinasePROSITE-ProRule annotationAdd BLAST257

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili716 – 1050Sequence analysisAdd BLAST335

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi310 – 446Ser-richSequence analysisAdd BLAST137
Compositional biasi1093 – 1098Poly-HisSequence analysis6

Sequence similaritiesi

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.By similarity

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0576 Eukaryota
ENOG410XP9G LUCA
InParanoidiQ55GC2
KOiK08837
OMAiLRDHTAW

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q55GC2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANIAALEPF VGKEDPVELF ELIEEIAEGS FGTVYKGKHL PTGNIMAVKI
60 70 80 90 100
IALDEDETFE DLVVEIDILN RCNHNNIVKY YGSWVKGDEL FIAMECCGGG
110 120 130 140 150
SITEIYQELN IPLNESQIAY VCRETLKGLE YLHHTNVIHR DLKGANILLT
160 170 180 190 200
ESGDVKLADF GVSGLLDKSS KRNTFIGTPY WMAPEVIENR SNPVPYDTKA
210 220 230 240 250
DIWSLGITLI ELAEAEPPLS EIHPMKVLFQ IPYRDPPKLK NQENYSKDFI
260 270 280 290 300
NFIQSCLQKD PNQRKTATEL LKHPFVTNTK EKAVLTDLIT KYRKFRAAEL
310 320 330 340 350
EEGGDEDEDS SEQEGMDSDD KDSDLKKSVG TSDRKSTLIA NGSTSSLSPP
360 370 380 390 400
ASPSQRKSTG QNLQLPQIIE QQSSSSSSSS SSSLSSQSLQ PQAVNKSTDR
410 420 430 440 450
LSANINGSNT KSNTIDKKTT AAASASASSL NLSTGNLQQS LSGSGSITTN
460 470 480 490 500
SGVGNGTSGK PTTNGKSSDD RSPDIRTNRK AGRPVTIRKT LEKRNDAVKK
510 520 530 540 550
IVNAKLMKQQ LKDIKKQQQK QQEEEEQLLK QQQKEKDDLL KQNAAKATQQ
560 570 580 590 600
QKQSAAKEEK IQKQHKVEKE TLSRQQKADR EQLLKKNQSD CSKQRTKVTD
610 620 630 640 650
QQKQQQREFK DQQKQQQKQK EHEFKDQNKV LDKSTPKKLS KHIAIHQKVI
660 670 680 690 700
REQEICVQDL VFQQKQDFQK LVDDHQNATQ NLFLENKQQS EQLFAWHTQQ
710 720 730 740 750
NQQFQFQQQC QLENYQEYHT VLRENMNAEH QLAKSQLEHS HLSETNHLKE
760 770 780 790 800
RQVTETEQHI KQMTTEQRNS LKEFKLKQTQ DFKEFLNKLK KELKDEKGNK
810 820 830 840 850
KQLQQQHKEQ KKQFELTLST QEVDFQKKQA RQKEEEDDIL LTHQKESFKR
860 870 880 890 900
LQDKQQNIIR DIEEHCKLQR QQFETEYTFN EEEMLIEHYR QKKALLKQQH
910 920 930 940 950
SEQKQIYQEQ TQLQYRLLQE QHKESPALLT DQHLKQKESI EEQQKERLTL
960 970 980 990 1000
QQEEHRIQQE SLKKQEQKKK GSVTDLPASL ASMQLEQSKQ LQLLSEQLQA
1010 1020 1030 1040 1050
ELATMFERHT KETQSLQAEL AKAQEKLQSD QQKLLHDLTE EQKKSKLKLK
1060 1070 1080 1090 1100
SESPSCKENP LHMKKKSTGT TPPSTSSNQK TLNNSNGASS NGHHHHHHQS
1110 1120 1130 1140
AGVGGSGGTI SSSHNTPVLP HNMKHQRSFS TSLPSFKFDN QD
Length:1,142
Mass (Da):130,779
Last modified:May 24, 2005 - v1
Checksum:iFF73CFD79066A65F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000003 Genomic DNA Translation: EAL73318.1
RefSeqiXP_647262.1, XM_642170.1

Genome annotation databases

EnsemblProtistsiEAL73318; EAL73318; DDB_G0267730
GeneIDi8616067
KEGGiddi:DDB_G0267730

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000003 Genomic DNA Translation: EAL73318.1
RefSeqiXP_647262.1, XM_642170.1

3D structure databases

ProteinModelPortaliQ55GC2
SMRiQ55GC2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0216378

Proteomic databases

PaxDbiQ55GC2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL73318; EAL73318; DDB_G0267730
GeneIDi8616067
KEGGiddi:DDB_G0267730

Organism-specific databases

dictyBaseiDDB_G0267730 dst2

Phylogenomic databases

eggNOGiKOG0576 Eukaryota
ENOG410XP9G LUCA
InParanoidiQ55GC2
KOiK08837
OMAiLRDHTAW

Miscellaneous databases

PROiPR:Q55GC2

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDST2_DICDI
AccessioniPrimary (citable) accession number: Q55GC2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: May 24, 2005
Last modified: February 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again