UniProtKB - Q55BC0 (ABCA8_DICDI)
Protein
ABC transporter A family member 8
Gene
abcA8
Organism
Dictyostelium discoideum (Slime mold)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 553 – 560 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase-coupled transmembrane transporter activity Source: GO_Central
- ATP binding Source: UniProtKB-KW
- lipid transporter activity Source: GO_Central
GO - Biological processi
- lipid transport Source: GO_Central
Keywordsi
Biological process | Transport |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: ABC transporter A family member 8Alternative name(s): ABC transporter ABCA.8 |
Gene namesi | Name:abcA8 ORF Names:DDB_G0271138 |
Organismi | Dictyostelium discoideum (Slime mold) |
Taxonomic identifieri | 44689 [NCBI] |
Taxonomic lineagei | Eukaryota › Amoebozoa › Evosea › Eumycetozoa › Dictyostelia › Dictyosteliales › Dictyosteliaceae › Dictyostelium |
Proteomesi |
|
Organism-specific databases
dictyBasei | DDB_G0271138, abcA8 |
Subcellular locationi
- Membrane Curated; Multi-pass membrane protein Curated
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 29 – 49 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 244 – 264 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 303 – 323 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 326 – 346 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 356 – 376 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 393 – 413 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 455 – 475 | HelicalSequence analysisAdd BLAST | 21 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- intracellular membrane-bounded organelle Source: GO_Central
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000363840 | 1 – 837 | ABC transporter A family member 8Add BLAST | 837 |
Proteomic databases
PaxDbi | Q55BC0 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 516 – 750 | ABC transporterPROSITE-ProRule annotationAdd BLAST | 235 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 339 – 342 | Poly-Ser | 4 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0059, Eukaryota |
HOGENOMi | CLU_000604_19_5_1 |
InParanoidi | Q55BC0 |
OMAi | DARHETW |
PhylomeDBi | Q55BC0 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR026082, ABCA IPR027417, P-loop_NTPase |
PANTHERi | PTHR19229, PTHR19229, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50893, ABC_TRANSPORTER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q55BC0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSIGETIHRE FIHLKLLLKK NFLVSIRSYF STIIELLSPI VFVLIFYIIY
60 70 80 90 100
SYGSAVDYSN VSYEQNLPNC IVSVENRCIN LMFSPMNSTC TVEIMKILAK
110 120 130 140 150
NNNMEIYNYP TDTGPLPNLE NTIGFHGGII AMDSLNSTEQ FILAHPNVTL
160 170 180 190 200
AVVDFENFPL NFTINGVKPN DSLIGFNDFY DLSFNVLLNL STSGGFIEPV
210 220 230 240 250
DYSIPVTTSI QKAIYDFYAI NNQKQIPTIN FDSTQFIEYS SVNVVSLFGG
260 270 280 290 300
LFYYCAIMIS FIFLLYKVAF EKEKNLKQGM VMMGLSRSMY WLSWVITSFT
310 320 330 340 350
IDLIICLLLI AIGAICKLPF FLGTNFLVLL LNFFLFAISS SSMAFFMLTF
360 370 380 390 400
IGKTKVAIGI GMAFFIVGSG LQLTFNSLGS LIFQIIYQTD SNGAAFVRVI
410 420 430 440 450
LFILPMFHFS KVLTDINDKV QSYPTSQFKI SDLNDNLDGS QYGMDYLVPT
460 470 480 490 500
TGQSLAYMFI LVIVYLSLSA IIEYALSGGF SFKTVKHINV PHFDDQDVAN
510 520 530 540 550
ATNRSLDPSN KSPFIIRGLS KTFNKFLRPS KSVHALKYLS LDIQEGTVLG
560 570 580 590 600
LLGSNGAGKS TTIGILTGIH SPTSGDAIIY GHSVVKDIHS VRKITSVVPQ
610 620 630 640 650
DDILWLELTA MEHLHLFAEL KGIPVRERDF QIAKVLEQVK LTKVANDQCS
660 670 680 690 700
TFSGGMKRRL SVAIGCIGDP KIIFMDEPTT GLDPRSKRRI YTLVKEIKKD
710 720 730 740 750
KVIILTSHDM HEIEILAQNL VILNDGIMVC NGNALQLKTK YGEGYSVQVI
760 770 780 790 800
AKSLEVIPEI INFVTSSLPY CRFLKQSALQ LNFGFPINTD PKIIVNFFKR
810 820 830
LESITKDENN NLMRDWSISH SNMDDVFIKV SNKPKLQ
Sequence cautioni
The sequence AAL85301 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF465310 Genomic DNA Translation: AAL85301.1 Sequence problems. AAFI02000006 Genomic DNA Translation: EAL71699.1 |
RefSeqi | XP_645692.1, XM_640600.1 |
Genome annotation databases
EnsemblProtistsi | EAL71699; EAL71699; DDB_G0271138 |
GeneIDi | 8617885 |
KEGGi | ddi:DDB_G0271138 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF465310 Genomic DNA Translation: AAL85301.1 Sequence problems. AAFI02000006 Genomic DNA Translation: EAL71699.1 |
RefSeqi | XP_645692.1, XM_640600.1 |
3D structure databases
SMRi | Q55BC0 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 44689.DDB0216250 |
Proteomic databases
PaxDbi | Q55BC0 |
Genome annotation databases
EnsemblProtistsi | EAL71699; EAL71699; DDB_G0271138 |
GeneIDi | 8617885 |
KEGGi | ddi:DDB_G0271138 |
Organism-specific databases
dictyBasei | DDB_G0271138, abcA8 |
Phylogenomic databases
eggNOGi | KOG0059, Eukaryota |
HOGENOMi | CLU_000604_19_5_1 |
InParanoidi | Q55BC0 |
OMAi | DARHETW |
PhylomeDBi | Q55BC0 |
Miscellaneous databases
PROi | PR:Q55BC0 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR026082, ABCA IPR027417, P-loop_NTPase |
PANTHERi | PTHR19229, PTHR19229, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50893, ABC_TRANSPORTER_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ABCA8_DICDI | |
Accessioni | Q55BC0Primary (citable) accession number: Q55BC0 Secondary accession number(s): Q8T6I9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 10, 2009 |
Last sequence update: | May 24, 2005 | |
Last modified: | December 2, 2020 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Dictyostelium discoideum
Dictyostelium discoideum: entries, gene names and cross-references to dictyBase - SIMILARITY comments
Index of protein domains and families