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Entry version 108 (18 Sep 2019)
Sequence version 1 (24 May 2005)
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Protein

Probable serine/threonine-protein kinase ifkA

Gene

ifkA

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Phosphorylates eIF2-alpha, from 1 to 7 hours after the onset of development or during the preaggregation state, resulting in a shift from polysomes to free ribosomes for bulk mRNA.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei348ATPPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei498Proton acceptorBy similarity1
Binding sitei923ATPPROSITE-ProRule annotation1
Active sitei1313Proton acceptorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi325 – 333ATPPROSITE-ProRule annotation9
Nucleotide bindingi900 – 908ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: dictyBase
  • eukaryotic translation initiation factor 2alpha kinase activity Source: dictyBase
  • protein kinase activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable serine/threonine-protein kinase ifkA (EC:2.7.11.1)
Alternative name(s):
Initiation factor kinase A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ifkA
ORF Names:DDB_G0272837
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0272837 ifkA

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

IfkA null cells have defects such as an earlier aggregation, a formation of larger than normal mounds and ultimately a formation of fruiting bodies that are also larger than normal. The early aggregation phenotype reflects an apparent, earlier than normal establishment of the cAMP pulsing system. Cells lacking ifkA and ifkB display severe morphological and patterning defects. Mutant cells aggregate in streams that give tightly clumped mounds. Fingers form from the mounds but remain attached to one another, especially at their bases. The fingers culminate to give fused and entangled structures lacking proper stalk but containing some spores.2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003620111 – 2258Probable serine/threonine-protein kinase ifkAAdd BLAST2258

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q558U1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expression dramatically drops soon after the onset of development and remains at a low level for the remainder of development.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0185218

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q558U1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini319 – 691Protein kinase 1PROSITE-ProRule annotationAdd BLAST373
Domaini894 – 1482Protein kinase 2PROSITE-ProRule annotationAdd BLAST589

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili273 – 309Sequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi51 – 58Poly-Asn8
Compositional biasi59 – 72Poly-AspAdd BLAST14
Compositional biasi143 – 150Poly-Ser8
Compositional biasi202 – 211Poly-Thr10
Compositional biasi212 – 277Poly-AsnAdd BLAST66
Compositional biasi287 – 292Poly-Asn6
Compositional biasi298 – 302Poly-Asn5
Compositional biasi358 – 361Poly-Ser4
Compositional biasi367 – 398Poly-AsnAdd BLAST32
Compositional biasi550 – 567Poly-AsnAdd BLAST18
Compositional biasi568 – 571Poly-Thr4
Compositional biasi620 – 639Gln-richAdd BLAST20
Compositional biasi746 – 753Poly-Asn8
Compositional biasi794 – 872Pro-richAdd BLAST79
Compositional biasi850 – 868Poly-ThrAdd BLAST19
Compositional biasi1060 – 1064Poly-Ser5
Compositional biasi1101 – 1106Poly-Lys6
Compositional biasi1155 – 1166Poly-AsnAdd BLAST12
Compositional biasi1211 – 1214Poly-Asp4
Compositional biasi1217 – 1220Poly-Asp4
Compositional biasi1902 – 1915Poly-AsnAdd BLAST14
Compositional biasi2064 – 2069Poly-Gly6
Compositional biasi2078 – 2084Poly-His7
Compositional biasi2134 – 2138Poly-Ser5

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1035 Eukaryota
COG0124 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q558U1

KEGG Orthology (KO)

More...
KOi
K16196

Identification of Orthologs from Complete Genome Data

More...
OMAi
EIEMIGK

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q558U1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.800, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036621 Anticodon-bd_dom_sf
IPR041715 HisRS-like_core
IPR024435 HisRS-related_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12745 HGTP_anticodon2, 1 hit
PF00069 Pkinase, 3 hits
PF13393 tRNA-synt_His, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00220 S_TKc, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56112 SSF56112, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q558U1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPGEIIIFE LCQAVQEFLL LYNKETVSLH EEMIKRLNTN INRVNSSDDI
60 70 80 90 100
NNNNNNNNDD DDDNDDYDDS DDENSDSDYD DYDDSDDENS DDEFYSDDED
110 120 130 140 150
YNTRHQMGDI GSSVNKIINS IDHTISHGGG VGVGIGSGNG LFSKSSSSSS
160 170 180 190 200
PMIPYNFSFD SLNGFDPDII FEDSFQTPLK GSSSIDFEEM NNLTNSNNSN
210 220 230 240 250
STATTTTTTT TNNNNNNNTN NNNNNNSNNN NNNNNNNNNT NNNTNNNNNN
260 270 280 290 300
NNNNNNNNNN NNNNNNNNNN NSNNNNNISN NKINKINNNN NNKELIDNNN
310 320 330 340 350
NNKDKENDLI NDTIPKIKWK KGSCIERKSN YSVYRGVDED TDRKLICKIV
360 370 380 390 400
NLNIDDRSSS SLTSLSNSNN NNSNNNNNNN NNNNNNNNNN NNNNNNNNLS
410 420 430 440 450
IDVVELKKRL IEKVKMIQKE IESMKYLGNP YIIKYLGTNF QEGQNTLYIF
460 470 480 490 500
QEYNSTLTLQ QKILSNGIGF EESQVKKFTY QLLLGLLYLH SQHIPHRDFK
510 520 530 540 550
SHNIFFNQST SKMLLSNYGG RNIKIFDHFE KLNSLKNLNS WISSTNNSIN
560 570 580 590 600
NINNINNNNN NNNNNINTTT TQNQINNEID RREDIINLGI VVLEMLCGSD
610 620 630 640 650
LANNQTVLIY LAQLNLLNNQ QQNQNFIQPP PLQYQLQQQY DLIKEIEQKT
660 670 680 690 700
HPSSPISNNA KDFLSLCFTI NGNGSTNDSL EAGILLKHPF LASNSNSTPP
710 720 730 740 750
PSNFLNFTNN IKFLDQRSAA TQALLSSPHS LIPQPIQTLI KSQTPNNNND
760 770 780 790 800
NNNLASSNEL LSSSNGSNID LRSTNSSIVS NPLATSSSLD NITPPPSRPI
810 820 830 840 850
SPKPSPLNKR NQKLQTSQQK PPLSPPQTPL KQIPQSPQSP PQQNFNTPPT
860 870 880 890 900
TTTTTTTPTA TPTTPTMTPL TPIQKQQQID YDMFRYHSRY RTDFEEIEMI
910 920 930 940 950
GKGGFGVVVK SRNKLDCRYY AIKKIKTKGY TDSNQEPLTN KLLREVTTLS
960 970 980 990 1000
RLHHQFVVRY YQAWIEKSCD SFQSLEEGNE DLSGDLETDA SEDWFMQSSI
1010 1020 1030 1040 1050
NSRSIISRDS YSGLSTSNSN VGGVNNTAGG GDSVSNANSN KSMIVGNSNK
1060 1070 1080 1090 1100
KLTLSSSNTS SSSSLLSNNK SKILNTSKST STNTSTSTST SNTNKNKKIS
1110 1120 1130 1140 1150
KKKKSKLSPL MKPKNKKNKN NGESEQSSSD SENGENGMKS RIIENASDSY
1160 1170 1180 1190 1200
SDDDNNNNNN NDNNNNYHSD NESDSFSGSI SMSDGNGSGY EATDDEDIIN
1210 1220 1230 1240 1250
NSGSFDENEN DDDDEEDDDD EYDEEDDDYE TFDFQDKSRV VSNNSKLSTS
1260 1270 1280 1290 1300
SSRKKPPKET HTLYIQMEYC SKKTLKTLID NVGGIAEEEA FRLLRQIVEG
1310 1320 1330 1340 1350
LNHIHSQQII HRDLKPANIF IDNEQNVKIG DFGLATSGAP VSKSDDLNSS
1360 1370 1380 1390 1400
TSNTANNINL SSSTNSTAQQ TPMWDLNDEN LSMTGGVGTP FYCCPEILEK
1410 1420 1430 1440 1450
NTKHYGTKVD MYSLGIIFFE MCFQFQTQME RSNILRDLRD NLKFPPGFES
1460 1470 1480 1490 1500
TKPDQTQIIR SLLSRDPTQR PSTKQLLESG LLPSKMEDDI LKEAIKTIAN
1510 1520 1530 1540 1550
PTISLFSYLM EKLFCLSNDE HIMSRYLYTS NPSLTPMHLI CREKTFSRLE
1560 1570 1580 1590 1600
KIFLNHGSIR IDTPTLFPKN PTNSTHPGAA NVAKFLDESG TVVYLPYDLT
1610 1620 1630 1640 1650
IPWARHVVIH NIQQAKRYTF SKVYRRSQPG FSPKELYECD FDIIGPSKSR
1660 1670 1680 1690 1700
HISDAETLRI IIEIMEEFKD ELFGNNSGSN SGSGSGGSIN YKIRINHYGL
1710 1720 1730 1740 1750
LDSILSECGV EKRFFTVVYQ TVAQLHWRLN WAQVAQSLKE HGLSASIVSN
1760 1770 1780 1790 1800
ISTYFRQRGE LAQCVTQLES LLANHKEATT GISDLKILVR NLQMINIIPR
1810 1820 1830 1840 1850
FLLDLSLIHN HQYYEGLVFQ AYIERPTLSN PSRTEIIMSG GRYDKLIKSL
1860 1870 1880 1890 1900
HPNPSLSNNI VSGVGVTLAC EKIVNSVLNY RQHLLNNCFN TTYTRRNKDP
1910 1920 1930 1940 1950
PNSNNNPNNN NLNNNVSIFT KFQSHIEVFV CSLGSSLLGE KLQVASQLWS
1960 1970 1980 1990 2000
AGIKADYSQT DYYSSEDIYS NCRENGIPWV VILREKAFQI GKLKVKQIET
2010 2020 2030 2040 2050
RQERTVARKD LVDFFLKSRK HNVDSKNIIQ NTSSSDLSNL IGGINNSGSG
2060 2070 2080 2090 2100
GSGGSGGGSS MSSGGGGGGN SNIGGSDHHH HGHHSNQSTS SSGNSNNSNT
2110 2120 2130 2140 2150
QQTSPIQHHV HFSNTKSIIG SSGIISNATF SGGSSSSSNI IHFDEPTDSF
2160 2170 2180 2190 2200
STQIVYQGVE EIKKSKIETL VQTSLSKLFR GFIQSKSSTI RVIVTDLAYS
2210 2220 2230 2240 2250
VIRDLQISES HDNISKFQRV SKEKLLQLKN QIFKWKVYPF IVIHSIKDDK

SVIFNSVV
Length:2,258
Mass (Da):252,390
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2A947A361D057E07
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000008 Genomic DNA Translation: EAL71056.1

NCBI Reference Sequences

More...
RefSeqi
XP_644975.1, XM_639883.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL71056; EAL71056; DDB_G0272837

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8618652

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0272837

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000008 Genomic DNA Translation: EAL71056.1
RefSeqiXP_644975.1, XM_639883.1

3D structure databases

SMRiQ558U1
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0185218

Proteomic databases

PaxDbiQ558U1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL71056; EAL71056; DDB_G0272837
GeneIDi8618652
KEGGiddi:DDB_G0272837

Organism-specific databases

dictyBaseiDDB_G0272837 ifkA

Phylogenomic databases

eggNOGiKOG1035 Eukaryota
COG0124 LUCA
InParanoidiQ558U1
KOiK16196
OMAiEIEMIGK
PhylomeDBiQ558U1

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q558U1

Family and domain databases

Gene3Di3.40.50.800, 1 hit
InterProiView protein in InterPro
IPR036621 Anticodon-bd_dom_sf
IPR041715 HisRS-like_core
IPR024435 HisRS-related_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF12745 HGTP_anticodon2, 1 hit
PF00069 Pkinase, 3 hits
PF13393 tRNA-synt_His, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 2 hits
SUPFAMiSSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIFKA_DICDI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q558U1
Secondary accession number(s): Q86B04
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 24, 2005
Last modified: September 18, 2019
This is version 108 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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