Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 83 (02 Jun 2021)
Sequence version 1 (02 May 2006)
Previous versions | rss
Add a publicationFeedback
Protein

Trafficking protein particle complex subunit 10

Gene

trapcc10-1

more
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in vesicular transport from endoplasmic reticulum to Golgi.

By similarity

Caution

The gene for this protein is duplicated in strains AX3 and AX4. These strains contain a duplication of a segment of 750 kb of chromosome 2 compared to the corresponding sequence in strain AX2.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processER-Golgi transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DDI-204005, COPII-mediated vesicle transport
R-DDI-8876198, RAB GEFs exchange GTP for GDP on RABs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Trafficking protein particle complex subunit 10
Alternative name(s):
Trafficking protein particle complex subunit TMEM1
Transport protein particle subunit TMEM1
Short name:
TRAPP subunit TMEM1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:trapcc10-1
Synonyms:tmem1-1
ORF Names:DDB_G0273209
AND
Name:trapcc10-2
Synonyms:tmem1-2
ORF Names:DDB_G0273719
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyosteliaDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0273209, trappc10-1
DDB_G0273719, trappc10-2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Golgi apparatus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003314811 – 1442Trafficking protein particle complex subunit 10Add BLAST1442

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q556Z3

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the multisubunit TRAPP (transport protein particle) complex.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0302652

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q556Z3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 86DisorderedSequence analysisAdd BLAST86
Regioni251 – 277DisorderedSequence analysisAdd BLAST27
Regioni535 – 564DisorderedSequence analysisAdd BLAST30
Regioni1208 – 1238DisorderedSequence analysisAdd BLAST31
Regioni1316 – 1335DisorderedSequence analysisAdd BLAST20
Regioni1422 – 1442DisorderedSequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TMEM1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1931, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006790_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q556Z3

Identification of Orthologs from Complete Genome Data

More...
OMAi
DAEFWDD

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022233, TRAPP_II_complex_TRAPPC10

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12584, TRAPPC10, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q556Z3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNVSPNSMN LNGSTSSTAS VNDSGGGGGG GNVTSPTLSS SSASSISNSN
60 70 80 90 100
SSSSNNLKPS TQPLSSSSTL NTPTQFSLQH SSSSSSLNNT NIDIIEHITI
110 120 130 140 150
SYQDESSIWK YIEAELPNHL PLKNISWKTK TGHTKVVEKM PIEILQYNDE
160 170 180 190 200
RVKAHYDNQN LYKKPYLYLY LVHCDDPDTY KNVVRAKIKQ WVTQMTERQQ
210 220 230 240 250
EWLIVYVSLG PKRFSELTSK LTRTVFDRIK NDFNVKRDRC CQLRFLDTNN
260 270 280 290 300
TSSGNNKDKD NDNGGGSSGT GLSTSTKQQD DLWDDFLIKM KEGIISSAEQ
310 320 330 340 350
YLTTYEDEIR KMDAKRTTPG WSYQNFFFIK EGLALIYERA QLYEDALMQY
360 370 380 390 400
FELEVLFGDP NNRSQFDQIT DEVLQPNSIH CNGNILDTSF KNYRKLIYEN
410 420 430 440 450
KISLFDFKVY LFARQSKLLF LLQKPIEAAT KSISFITSMS MIIKQYPNSF
460 470 480 490 500
APMFKESWIF STSMELIKAC QDSFDKIVNG AQQQQQQQQQ QLQLQQQLQQ
510 520 530 540 550
QQQQQTINGS AQKVVKSISS TTPISKLFGA FGPFGSSSSN TPSSTSATTA
560 570 580 590 600
ANGKNTPMPS NSGIASLSAG GSTIIAGLSG SQSLNNLQSA QLSGALNTQH
610 620 630 640 650
YIRTPSLNLT SDLSERLTEK QDRESLDFLV GDLLFSSAQR LEELAIIIGY
660 670 680 690 700
LPVDDYNSEM FFQNVEEVIF KSVENKKIEV DSMTAFSYQP LQVSLQSSKQ
710 720 730 740 750
FTQLYFELLG QIEKLYIQSN RMRSISRLTF AIANLNFKLK EFQIAENLFK
760 770 780 790 800
SISNLYSREH WSYIEYAVKT RLSYCQKQLG HLVDYVTTCV GLLAPGLLTN
810 820 830 840 850
RFEKDHYLSE IIQISRKPEL NIVQPMIPLF KCKVTFKETV YRYFETIKIN
860 870 880 890 900
VRIKSNLISP IRFNNGAVSF VKSGFGDKLV FQLNDFLVEP GVNNFQFTAV
910 920 930 940 950
GTTKATFVKD SIWLKIDNLS FGYSLRNADT AIGGGGGGTN TTTTTLPGEI
960 970 980 990 1000
KVIDSESQIT LESFANSPLL FYSIQYVGIK LHTHSDTIEA GVLTFTSPTG
1010 1020 1030 1040 1050
ATIIPTSSVI IIQSDDKTCE TSSRTINLIN DKLPLSQIGY NQTLEFYLPL
1060 1070 1080 1090 1100
MAVNTDTCTH QIRIELQHQK QTKEKFSSSL VSSILFINPL TIDESVINVN
1110 1120 1130 1140 1150
NRLFLKTIIQ CNSPNMIQFN SYSLEGCDSE YQSPEQQQLQ QQLQQQQQLS
1160 1170 1180 1190 1200
LSSSSSSISS ISSKSSQQPN LYYLVKDHNH SLAPNLNLYP GQLVSLIFEI
1210 1220 1230 1240 1250
KKYENESLSS STSPSSATDS SNSNGNNNNN NNNNNHSKND LKLKIKYTSK
1260 1270 1280 1290 1300
MPQQDLDRPL IRECKSLWRD QNEFSWPIKI ELPTYLYQID LSIQSRAYVG
1310 1320 1330 1340 1350
TIVLFEIEIT NLKQQQQQQK ESNNDNGNEK QQKQQQLQYH IVADSQIWMI
1360 1370 1380 1390 1400
SGKSKHTFSF NSDTVGEKLK FSCGLIPISS GSLPIPKVTL VGINNSNISY
1410 1420 1430 1440
PKTKNEKIFV YPSPQIYSCH QLQDNNNNNN NSINSQTSTN KT
Length:1,442
Mass (Da):162,300
Last modified:May 2, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i525FD0B8F4A96FA1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000011 Genomic DNA Translation: EAL70550.1
AAFI02000009 Genomic DNA Translation: EAL70822.1

NCBI Reference Sequences

More...
RefSeqi
XP_644476.1, XM_639384.1
XP_644774.1, XM_639682.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL70550; EAL70550; DDB_G0273719
EAL70822; EAL70822; DDB_G0273209

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8618876
8619100

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0273209
ddi:DDB_G0273719

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000011 Genomic DNA Translation: EAL70550.1
AAFI02000009 Genomic DNA Translation: EAL70822.1
RefSeqiXP_644476.1, XM_639384.1
XP_644774.1, XM_639682.1

3D structure databases

SMRiQ556Z3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0302652

Proteomic databases

PaxDbiQ556Z3

Genome annotation databases

EnsemblProtistsiEAL70550; EAL70550; DDB_G0273719
EAL70822; EAL70822; DDB_G0273209
GeneIDi8618876
8619100
KEGGiddi:DDB_G0273209
ddi:DDB_G0273719

Organism-specific databases

dictyBaseiDDB_G0273209, trappc10-1
DDB_G0273719, trappc10-2

Phylogenomic databases

eggNOGiKOG1931, Eukaryota
HOGENOMiCLU_006790_0_0_1
InParanoidiQ556Z3
OMAiDAEFWDD

Enzyme and pathway databases

ReactomeiR-DDI-204005, COPII-mediated vesicle transport
R-DDI-8876198, RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q556Z3

Family and domain databases

InterProiView protein in InterPro
IPR022233, TRAPP_II_complex_TRAPPC10
PfamiView protein in Pfam
PF12584, TRAPPC10, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTPC10_DICDI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q556Z3
Secondary accession number(s): Q86AI7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 2, 2006
Last modified: June 2, 2021
This is version 83 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again