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Entry version 96 (03 Jul 2019)
Sequence version 1 (24 May 2005)
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Protein

Myb-like protein H

Gene

mybH

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi857Zinc; catalyticPROSITE-ProRule annotation1
Metal bindingi859Zinc; catalyticPROSITE-ProRule annotation1
Metal bindingi870Zinc; catalyticPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi172 – 195H-T-H motifPROSITE-ProRule annotationAdd BLAST24
DNA bindingi252 – 275H-T-H motifPROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Hydrolase, Metalloprotease, Protease
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Protein family/group databases

MEROPS protease database

More...
MEROPSi
M67.A12

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Myb-like protein H
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mybH
ORF Names:DDB_G0277927
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0277927 mybH

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003293831 – 1217Myb-like protein HAdd BLAST1217

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q54Z40

PRoteomics IDEntifications database

More...
PRIDEi
Q54Z40

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0220617

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q54Z40

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini145 – 199HTH myb-type 1PROSITE-ProRule annotationAdd BLAST55
Domaini225 – 279HTH myb-type 2PROSITE-ProRule annotationAdd BLAST55
Domaini525 – 624SWIRMPROSITE-ProRule annotationAdd BLAST100
Domaini778 – 921MPNPROSITE-ProRule annotationAdd BLAST144

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi857 – 870JAMM motifPROSITE-ProRule annotationAdd BLAST14

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi12 – 53Gln-richAdd BLAST42
Compositional biasi109 – 1072Asn-richAdd BLAST964
Compositional biasi339 – 479Ser-richAdd BLAST141
Compositional biasi1075 – 1171Ser-richAdd BLAST97
Compositional biasi1186 – 1203Asn-richAdd BLAST18

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0724 Eukaryota
KOG1279 Eukaryota
KOG1555 Eukaryota
COG1310 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q54Z40

KEGG Orthology (KO)

More...
KOi
K11865

Identification of Orthologs from Complete Genome Data

More...
OMAi
KNHARIY

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00167 SANT, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009057 Homeobox-like_sf
IPR000555 JAMM/MPN+_dom
IPR037518 MPN
IPR017930 Myb_dom
IPR006447 Myb_dom_plants
IPR001005 SANT/Myb
IPR007526 SWIRM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01398 JAB, 1 hit
PF00249 Myb_DNA-binding, 2 hits
PF04433 SWIRM, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00232 JAB_MPN, 1 hit
SM00717 SANT, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 3 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01557 myb_SHAQKYF, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51294 HTH_MYB, 2 hits
PS50249 MPN, 1 hit
PS50934 SWIRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q54Z40-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTQTKTSSP IQPSPIEQSP IQQSPIQQSP IQQSPILQSP IQRSPIQQLP
60 70 80 90 100
IQQSPSISST SFSNSNNDTN FNSKRLSNSI FPTSTSPVLS PLSPPLQPQP
110 120 130 140 150
LISTSTSFNI NNNNNNNNNN NNNNNNNNNN NNNNNNNNNT PKTTISGATR
160 170 180 190 200
SSWTKEEERL FVEAYKLYDK DNKKIQEHVK TKTILQVRSH AQKFALKLEK
210 220 230 240 250
NGIKSLDNID QLFNQSHAAS SSHNLPSHNT PWSNEEHELF LKAIEKYGRG
260 270 280 290 300
NWKLISTLIK SRNTLQIKNH ARIYFDKISQ QNGPPSKKTI IEVENNNNYN
310 320 330 340 350
DQNNNNEQNN NNNNNNNNNN NNNNNNNSFF NGNDNGNNSS YSDNGNGNKS
360 370 380 390 400
TSSKSDLSNT RSSGSSSSSG SSSSSSSSTI SSGGSGGRSS GGSSGRSSGN
410 420 430 440 450
SKKSSSKSKS KNPTSKPITP IQPKLILPSR NIILSSAFST PTPTSISTFP
460 470 480 490 500
KTPTYTTSNY KSSNNPLNRS FGSINNSSSN NNNNNNNNNN NNNNNNNNNN
510 520 530 540 550
NNNNNNNNNN NNNNNNNNNN NNNNNKPPTK ERYLDLNIIT QEEMMGCKEY
560 570 580 590 600
FTGQISKTPD RYIKIRDKII RQWDSFKPNY LSKTFSRNQI KDCGSDINSI
610 620 630 640 650
GRVHQFLESI GVINFNAVGN PLNNNDYDRD NNNNNNNKNN NNNNNNNNNN
660 670 680 690 700
NNNNNNNNNI SDLSAILSSA ITNRMLENRK TNNPLRKRKI FYDGQWMDQS
710 720 730 740 750
LLNTTIEHSG NENDKINMAT SSTINNVNNS KTSSSSSPTN ESSKLYNFED
760 770 780 790 800
FSSFPSFDPF TLVECKKYNN PNEQPFTIDV SSNTMIVMDI HSHISSTEVI
810 820 830 840 850
GMLGGKFNPD TNHITILLAI PCNSISSDIQ CDMDPNSQIA AKEMVNSIGL
860 870 880 890 900
DIVGWYHSHP NFEPIPSLRD IETQTSFQNL FATSSNNNNN NNKSMIEPFI
910 920 930 940 950
GFIVNPYHKN GLISNFNCIT ITKQMDETNQ YRIPYQLSTS YTPSLNNQYL
960 970 980 990 1000
YQQIDNLFEK YKSYSSRIDL KKTMENGGFT HLDKMISSIS SNLILNNNSS
1010 1020 1030 1040 1050
SSNNKNNTNE SDLINCDEDI IQDDQTELFL TKIKNQFKDF NNNNNNNNNN
1060 1070 1080 1090 1100
NNNNNNNNNN NNNNNNKNKN RNEGSRSRSR SRSRSRSRSR SGTRSRSRSR
1110 1120 1130 1140 1150
SLDSYSRSRS RSGGNGYVGE KTLPKKHHHQ HLHNRHKSNT FNDPDLSDSY
1160 1170 1180 1190 1200
MSEVSRSSSD YYNTESSSSM SDIEDDDISE YSDTENYKSF NKNNNNNNHY
1210
NNNFLDKPVL QNKPSYQ
Length:1,217
Mass (Da):136,877
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i82568085181FD8E2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000023 Genomic DNA Translation: EAL68136.1

NCBI Reference Sequences

More...
RefSeqi
XP_642011.1, XM_636918.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL68136; EAL68136; DDB_G0277927

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8621224

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0277927

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000023 Genomic DNA Translation: EAL68136.1
RefSeqiXP_642011.1, XM_636918.1

3D structure databases

SMRiQ54Z40
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0220617

Protein family/group databases

MEROPSiM67.A12

Proteomic databases

PaxDbiQ54Z40
PRIDEiQ54Z40

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL68136; EAL68136; DDB_G0277927
GeneIDi8621224
KEGGiddi:DDB_G0277927

Organism-specific databases

dictyBaseiDDB_G0277927 mybH

Phylogenomic databases

eggNOGiKOG0724 Eukaryota
KOG1279 Eukaryota
KOG1555 Eukaryota
COG1310 LUCA
InParanoidiQ54Z40
KOiK11865
OMAiKNHARIY

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q54Z40

Family and domain databases

CDDicd00167 SANT, 2 hits
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR000555 JAMM/MPN+_dom
IPR037518 MPN
IPR017930 Myb_dom
IPR006447 Myb_dom_plants
IPR001005 SANT/Myb
IPR007526 SWIRM
PfamiView protein in Pfam
PF01398 JAB, 1 hit
PF00249 Myb_DNA-binding, 2 hits
PF04433 SWIRM, 1 hit
SMARTiView protein in SMART
SM00232 JAB_MPN, 1 hit
SM00717 SANT, 2 hits
SUPFAMiSSF46689 SSF46689, 3 hits
TIGRFAMsiTIGR01557 myb_SHAQKYF, 2 hits
PROSITEiView protein in PROSITE
PS51294 HTH_MYB, 2 hits
PS50249 MPN, 1 hit
PS50934 SWIRM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMYBH_DICDI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q54Z40
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: July 3, 2019
This is version 96 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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