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Entry version 100 (16 Oct 2019)
Sequence version 1 (24 May 2005)
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Protein

Probable serine/threonine-protein kinase roco6

Gene

roco6

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as a serine/threonine-protein kinase and guanine-nucleotide releasing factor.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei1383ATPPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1481Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi403 – 410GTPPROSITE-ProRule annotation8
Nucleotide bindingi634 – 638GTPPROSITE-ProRule annotation5
Nucleotide bindingi691 – 694GTPPROSITE-ProRule annotation4
Nucleotide bindingi1362 – 1370ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, GTP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable serine/threonine-protein kinase roco6 (EC:2.7.11.1)
Alternative name(s):
Ras of complex proteins and C-terminal of roc 6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:roco6
ORF Names:DDB_G0279417
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0279417 roco6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 1055ExtracellularSequence analysisAdd BLAST1055
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1056 – 1076HelicalSequence analysisAdd BLAST21
Topological domaini1077 – 2147CytoplasmicSequence analysisAdd BLAST1071

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003588921 – 2147Probable serine/threonine-protein kinase roco6Add BLAST2147

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q54WS5

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0214834

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati69 – 89LRR 1Add BLAST21
Repeati101 – 122LRR 2Add BLAST22
Repeati124 – 145LRR 3Add BLAST22
Repeati148 – 169LRR 4Add BLAST22
Repeati171 – 192LRR 5Add BLAST22
Repeati193 – 214LRR 6Add BLAST22
Repeati215 – 236LRR 7Add BLAST22
Repeati237 – 256LRR 8Add BLAST20
Repeati306 – 328LRR 9Add BLAST23
Repeati329 – 350LRR 10Add BLAST22
Repeati352 – 372LRR 11Add BLAST21
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini390 – 750RocPROSITE-ProRule annotationAdd BLAST361
Repeati1051 – 1098WD 1Add BLAST48
Repeati1237 – 1263LRR 12Add BLAST27
Repeati1274 – 1297LRR 13Add BLAST24
Repeati1325 – 1348LRR 14Add BLAST24
Domaini1356 – 1627Protein kinasePROSITE-ProRule annotationAdd BLAST272
Repeati1735 – 1774WD 2Add BLAST40
Repeati1778 – 1820WD 3Add BLAST43
Domaini1821 – 1923PHPROSITE-ProRule annotationAdd BLAST103
Repeati2031 – 2068WD 4Add BLAST38

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni390 – 750Small GTPase-likeAdd BLAST361

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi44 – 52Poly-Asn9
Compositional biasi62 – 67Poly-Asn6
Compositional biasi533 – 537Poly-Gly5
Compositional biasi610 – 616Poly-Asn7
Compositional biasi910 – 924Poly-AsnAdd BLAST15
Compositional biasi993 – 997Poly-Gly5
Compositional biasi1257 – 1264Poly-Pro8
Compositional biasi1278 – 1281Poly-Thr4
Compositional biasi1662 – 1665Poly-Gln4
Compositional biasi1673 – 1678Poly-Gln6

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Leucine-rich repeat, Repeat, Transmembrane, Transmembrane helix, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0192 Eukaryota
COG0515 LUCA
COG1100 LUCA
COG4886 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q54WS5

Identification of Orthologs from Complete Genome Data

More...
OMAi
IVLERIY

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q54WS5

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit
2.30.29.30, 1 hit
3.80.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032171 COR
IPR011009 Kinase-like_dom_sf
IPR001611 Leu-rich_rpt
IPR025875 Leu-rich_rpt_4
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR027417 P-loop_NTPase
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR011047 Quinoprotein_ADH-like_supfam
IPR020859 ROC_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008271 Ser/Thr_kinase_AS
IPR015943 WD40/YVTN_repeat-like_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16095 COR, 1 hit
PF12799 LRR_4, 1 hit
PF00169 PH, 1 hit
PF07714 Pkinase_Tyr, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00369 LRR_TYP, 7 hits
SM00233 PH, 1 hit
SM00220 S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50998 SSF50998, 1 hit
SSF52540 SSF52540, 1 hit
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51450 LRR, 9 hits
PS50003 PH_DOMAIN, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS51424 ROC, 1 hit
PS00678 WD_REPEATS_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q54WS5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNSIHKQHYT INSNHYNESI NINSLLLNDL NDEKRTTSTN NKSNNNSNNN
60 70 80 90 100
NNETLEDIIE FNNNNCNGDM KYLDLSKRMI YSLELMMIPE IENRFQGDFK
110 120 130 140 150
SISILNLNDN LLGEIPESLK QLTQLISLSI RGNHILEIPL WFPEEFKLLR
160 170 180 190 200
KLDVSHNAIS SVPNTFNKFS ILEDLNLSNN YISYIHPSLF PEGIMRLNLS
210 220 230 240 250
NNLFREVELP PWFESLLTLD ISGNKLKHLG NLPFHLVRVS IDDNHLESID
260 270 280 290 300
HKVILRNKDL ALKFNQSFSD IVLERIYQCW YTGDPVLDLS GLGMCVVPPI
310 320 330 340 350
LGMLVHLTHL DLSGNCISVL PPELANLTEL VRLDLSFNIL TTLPLYIVSY
360 370 380 390 400
KRLEHLDLQG TLDTLVSPPR RIAETGKLID IQRYFHDLFQ GEPSYRVKLM
410 420 430 440 450
IVGQENVGKT SLVKCLKMKK KFSKNSDHLG TNVSTDGIDI DEIKFNLDIE
460 470 480 490 500
LPSNPSSNSL ISNSLSNSSI SSNNINSNNN INVHSNGGGI NSNGVNSNSQ
510 520 530 540 550
ININSSSGNI HSNGGGVGNV NSSGGIHSNN SSGGGGGSNS FLNNTNSNGT
560 570 580 590 600
NNNSSNLNIN TNSNNVNSSG GGNNYHPPVG TNTSMSNIQV IGSSGSNLGS
610 620 630 640 650
GSNLSIGGSN GNNNNNSGGS GTMVNQRVTM SIWDCAGQEL YYTSHQMFLT
660 670 680 690 700
DSALYVVVWN LCKPEVNSRV EFWLHSIRSK AENAPILLIG THLDDYLATH
710 720 730 740 750
SESELDEILE NIYSKYFRKF RLKGISILSC STGVGFDNFL DLLKKTVVEL
760 770 780 790 800
PSLKQSLPEL YLKLEKLIIK KRSTLVPPVL TWQSFSQMVL SNLDFHDEIH
810 820 830 840 850
VKVATKALVP LGSISFFDEP GLDQYVFLDP QWLTGVFSSI ITTKHKFIKD
860 870 880 890 900
GVLKKSDLYQ IWKPPHFIED EGLHSLLINL LERFELMFPL DSDLVSLSSS
910 920 930 940 950
NGNNGNSYVN NNNNNNNNSN NNNNGSNKSS PFKTTPSSPS TLRLVDSKSK
960 970 980 990 1000
GSHSSNPILS GNNSSSKNST STKRSISGSP LRSRSNSDLD LIGGGGGSPI
1010 1020 1030 1040 1050
NGSSIDYSSK SNTLTPGLFN ELNQKFIIPS QLPEIRPSFG LLWPSLDHSR
1060 1070 1080 1090 1100
VEFNRWIQLS FAPAGLFSRL LIRLLISKEF DMKPILYWRN GVVVESQSGK
1110 1120 1130 1140 1150
SFLSTSTALI EMVPSYANCS STIKISVRGD RRTGRGLSAK LLRLIVEIAD
1160 1170 1180 1190 1200
TLCTSWYHLE TNQVIPCPHC INKPNCTLFS LSDCEAVASS GVWYLLCGDR
1210 1220 1230 1240 1250
KINFETFVPD VAMSDFWGSG SKKFNYDQIK MHKEKRILSI KPASFGNNQI
1260 1270 1280 1290 1300
QFEVRVPPSP PPPPVQQIIN NGADDNITTT TLAVNNIKVL ESGGSQPPSP
1310 1320 1330 1340 1350
RSGKDVTHEL PIINRLEIIQ PTSDESSLIQ VEFDHNNQTL VISGTYKYGD
1360 1370 1380 1390 1400
LLEIEFESPK LIGRGASGKI YRANLNDTMV AVKQLEVVGE DAPRIFSEFR
1410 1420 1430 1440 1450
REIHVMSDLK HSNVVNLLGF TLSPFTMVME YIDCGDLHKF LHSPIGDQLN
1460 1470 1480 1490 1500
GNWALILKLA LDIAKGMEFL HSVTPPLLHR DLKSPNVLLS MKDGVYTAKV
1510 1520 1530 1540 1550
GDFGLSSRMF IQALKHKLRN FPVGNITWVA PEILREEEYT VKSDVYAFGL
1560 1570 1580 1590 1600
ILHELLTRKH PYREFNYSMV SLQEDAIKNG LRPTISPSYT QTVTGHEYCG
1610 1620 1630 1640 1650
LIQDCWDSDI DRRPTFNKIV KRIKQIIGRD VNNILMVNGV SVVSGIQSPN
1660 1670 1680 1690 1700
SLADSQPFHY HQQQQPSLNS TNQLQQQQYS SVLTSPRSNL SDSSNSSQNI
1710 1720 1730 1740 1750
ANKSLNNISA TSLGDLGGND ENLGGQLQYS MRVPQPEAKV NQLVWEVNSR
1760 1770 1780 1790 1800
RVWGGCESGE IIVWNAENGN QIFREQKLHP GPIRSLALVN QEDIWSAGGI
1810 1820 1830 1840 1850
GPQQSTIRIW NAWRFNLDDQ SGTKSDFITK KGRGGSTFGR KSWRLRWFVL
1860 1870 1880 1890 1900
SRFDKTLKYY SKQTDKEPSC SLILEGAWLE EISPPGYKVS LHLIHPEKRT
1910 1920 1930 1940 1950
MEMEFKSESE KSSWLTAINR VINQNIPLYE IALGKQMTSG SENDYITNLL
1960 1970 1980 1990 2000
SVGPNVWVSL KETPSILVYN VKSKELVTKI SLNDDQSSDQ WGKTGAVNMM
2010 2020 2030 2040 2050
LVNNFVWITG GSKLTQIDSQ SYQLLEVHGN HYSKPITSMA LVEKNVWISC
2060 2070 2080 2090 2100
EDESLSVWDG DTGSFIRKVG SPIGSPTKPT VYTKLLYFSG YVWACTQGSI
2110 2120 2130 2140
HIYCIHSLTC KKKVESKNHP NSIVDLIKVF QQTVWSCCGT NNVCIWS
Length:2,147
Mass (Da):239,183
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD472CAAF5002514A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti2 – 17NSIHK…SNHYN → ISFLNHLYPINRNLYK in AAO83651 (PubMed:14654223).CuratedAdd BLAST16
Sequence conflicti28N → K in AAO83651 (PubMed:14654223).Curated1
Sequence conflicti39 – 57TNNKS…ETLED → PIIKGIIISIINNIEPLKN in AAO83651 (PubMed:14654223).CuratedAdd BLAST19
Sequence conflicti797 – 798DE → NQ in AAO83651 (PubMed:14654223).Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY232268 Genomic DNA Translation: AAO83651.1
AAFI02000031 Genomic DNA Translation: EAL67647.1

NCBI Reference Sequences

More...
RefSeqi
XP_641642.1, XM_636550.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL67647; EAL67647; DDB_G0279417

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8622048

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0279417

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY232268 Genomic DNA Translation: AAO83651.1
AAFI02000031 Genomic DNA Translation: EAL67647.1
RefSeqiXP_641642.1, XM_636550.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi44689.DDB0214834

Proteomic databases

PaxDbiQ54WS5

Genome annotation databases

EnsemblProtistsiEAL67647; EAL67647; DDB_G0279417
GeneIDi8622048
KEGGiddi:DDB_G0279417

Organism-specific databases

dictyBaseiDDB_G0279417 roco6

Phylogenomic databases

eggNOGiKOG0192 Eukaryota
COG0515 LUCA
COG1100 LUCA
COG4886 LUCA
InParanoidiQ54WS5
OMAiIVLERIY
PhylomeDBiQ54WS5

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q54WS5

Family and domain databases

Gene3Di2.130.10.10, 1 hit
2.30.29.30, 1 hit
3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR032171 COR
IPR011009 Kinase-like_dom_sf
IPR001611 Leu-rich_rpt
IPR025875 Leu-rich_rpt_4
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR027417 P-loop_NTPase
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR011047 Quinoprotein_ADH-like_supfam
IPR020859 ROC_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008271 Ser/Thr_kinase_AS
IPR015943 WD40/YVTN_repeat-like_dom_sf
PfamiView protein in Pfam
PF16095 COR, 1 hit
PF12799 LRR_4, 1 hit
PF00169 PH, 1 hit
PF07714 Pkinase_Tyr, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 7 hits
SM00233 PH, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF50998 SSF50998, 1 hit
SSF52540 SSF52540, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 9 hits
PS50003 PH_DOMAIN, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS51424 ROC, 1 hit
PS00678 WD_REPEATS_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiROCO6_DICDI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q54WS5
Secondary accession number(s): Q6XHB0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: May 24, 2005
Last modified: October 16, 2019
This is version 100 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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