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Entry version 102 (07 Oct 2020)
Sequence version 1 (24 May 2005)
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Protein

Hybrid signal transduction histidine kinase A

Gene

dhkA

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a receptor histidine kinase for the cytokinin SDF-2 in a signal transduction pathway that regulates prestalk gene expression and controls terminal differentiation of prespore cells. Binding of SDF-2 to this protein inhibits phosphorelay and induces rapid sporulation. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: dictyBase
  • phosphorelay sensor kinase activity Source: dictyBase
  • transmembrane receptor histidine kinase activity Source: dictyBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Kinase, Transferase
Biological processCytokinin signaling pathway, Differentiation, Sporulation
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Hybrid signal transduction histidine kinase A (EC:2.7.13.3)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dhkA
ORF Names:DDB_G0280961
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyosteliaDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0280961, dhkA

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei772 – 792HelicalSequence analysisAdd BLAST21
Transmembranei1098 – 1118HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi1396H → Q: Impaired function. Normal function; when associated with N-2076. 1 Publication1
Mutagenesisi2076D → N: Impaired function. Normal function; when associated with Q-1396. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003282041 – 2150Hybrid signal transduction histidine kinase AAdd BLAST2150

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1396Phosphohistidine; by autocatalysisPROSITE-ProRule annotation1
Modified residuei20764-aspartylphosphatePROSITE-ProRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q54U87

PRoteomics IDEntifications database

More...
PRIDEi
Q54U87

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed from 8 hours following initiation of development, prior to the appearance of mound tips. Subsequently persists throughout development.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SDF-2, an acbA peptide involved in sporulation.

1 Publication

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0215354

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q54U87

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini838 – 1082CHASEPROSITE-ProRule annotationAdd BLAST245
Domaini1235 – 1317PASAdd BLAST83
Domaini1321 – 1376PACAdd BLAST56
Domaini1393 – 1620Histidine kinasePROSITE-ProRule annotationAdd BLAST228
Domaini2026 – 2146Response regulatoryPROSITE-ProRule annotationAdd BLAST121

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1139 – 1164Sequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi33 – 66Poly-GlnAdd BLAST34
Compositional biasi75 – 81Poly-Gln7
Compositional biasi105 – 145Poly-AsnAdd BLAST41
Compositional biasi200 – 204Poly-Asn5
Compositional biasi212 – 243Poly-AsnAdd BLAST32
Compositional biasi305 – 317Poly-AsnAdd BLAST13
Compositional biasi412 – 436Poly-AsnAdd BLAST25
Compositional biasi472 – 475Poly-Asn4
Compositional biasi478 – 484Poly-Asn7
Compositional biasi525 – 528Poly-Asn4
Compositional biasi539 – 542Poly-Asn4
Compositional biasi565 – 577Poly-AsnAdd BLAST13
Compositional biasi588 – 600Poly-AsnAdd BLAST13
Compositional biasi657 – 675Poly-AsnAdd BLAST19
Compositional biasi678 – 727Poly-AsnAdd BLAST50
Compositional biasi1249 – 1253Poly-Gly5
Compositional biasi1715 – 1733Poly-AsnAdd BLAST19
Compositional biasi1866 – 1876Poly-GlyAdd BLAST11
Compositional biasi1889 – 1892Poly-Asn4
Compositional biasi1936 – 1939Poly-Gln4
Compositional biasi1942 – 1948Poly-Gln7
Compositional biasi1989 – 1992Poly-Asn4

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0519, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_231770_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q54U87

Identification of Orthologs from Complete Genome Data

More...
OMAi
SIMEIEC

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00082, HisKA, 1 hit
cd00130, PAS, 1 hit
cd00156, REC, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.565.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006189, CHASE_dom
IPR011006, CheY-like_superfamily
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR001610, PAC
IPR000014, PAS
IPR035965, PAS-like_dom_sf
IPR013655, PAS_fold_3
IPR004358, Sig_transdc_His_kin-like_C
IPR001789, Sig_transdc_resp-reg_receiver

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03924, CHASE, 1 hit
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF08447, PAS_3, 1 hit
PF00072, Response_reg, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00344, BCTRLSENSOR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01079, CHASE, 1 hit
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00086, PAC, 1 hit
SM00448, REC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 1 hit
SSF55785, SSF55785, 1 hit
SSF55874, SSF55874, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50839, CHASE, 1 hit
PS50109, HIS_KIN, 1 hit
PS50110, RESPONSE_REGULATORY, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q54U87-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MELKTFKDLN DDIIGDTSPV INTGDQPNPL RTQQQQLQQQ QQQQQQQQQQ
60 70 80 90 100
QQQQQQQQQQ QQQQQQHHIP QQLYQKQQQQ QHSHSYGNHS FIHNVSPTSP
110 120 130 140 150
SYDINNNNNN NNNNNNNNNN NNNNNNNSNN NNNNNNNNKN NYNNNYYYSP
160 170 180 190 200
IENSNISKSL EESVLNQFPH NFNLNSSNNN YLNNSSSLHN INQSVNSLSN
210 220 230 240 250
NNNNQTNQQP INNNNNNNNN NNNNNSNNSN NSNNNNNGNN NNNITDSPTK
260 270 280 290 300
SKRHSTYETN IGSHQRRKSI QSLIANSAIH SFSKLKNKPL SSSTPSTVNT
310 320 330 340 350
CGAVNNNSNN NNNNNNNSTG SLGAIPMDRS FDGNINTITE ESTGGNNSPR
360 370 380 390 400
SNCGSNCGSN GGIPLSPRNL SSLNSGVNVS PRNIHLNNLN NNSSNLPPLS
410 420 430 440 450
PRHINFHINV SNLNNNNNNN INPNNNPNNS NNSNNNVSPR NNNHNISPRG
460 470 480 490 500
SNISPRSNNG GSTTISPRNI SNNNNIINNI NNNNILTPPR NSPRLENVNP
510 520 530 540 550
TNSPRLLATS LNSTLPIVSS LTSSNNNNQS NNNTNPSINN NNGRNGHCIQ
560 570 580 590 600
TISEEILGNK PVVYNNGNNN NNNNTNNSTT SNNNITTNNN NNNNNNINNN
610 620 630 640 650
VLSTPRKRTK GNHSKTNSLQ DFETSSMNGG DDSISGAGSG GSLRRRNKDD
660 670 680 690 700
NDENDGNSNN TNSNNSNNNN NNNNNSSNNN NNNSNNNNNN NNNNNNNNNN
710 720 730 740 750
NNNNNNNNNN NNNNNNNNNN NNNNNNNYHN GATMMMSHNH QSIGMSSSPK
760 770 780 790 800
KNNFKPFSRN CSLMGMGRRA WAIILGLFIV GSSISILATL VLRYSEENSI
810 820 830 840 850
ADDFARVARD RFTMLRIEFN NRLYITQTLS LLLSVFPSTS EDQFVPFSKL
860 870 880 890 900
WSDNAEGLEG IMWAPRVSNL DRYTWEIEHS VKIREIVTNP NNSSDMRDVP
910 920 930 940 950
AAAASDYYPI LFSEPQSSND HFKGYNIYSD MWRRPSLNKT RDTGEKVSVA
960 970 980 990 1000
SPYINKLANV PKNSRSNVLL YIYQAVYTYG KVLSTVEDRR HEVIGFASCR
1010 1020 1030 1040 1050
FFISRMVSAS LQRLTEEDSL DLYVFDLDST PIGELIYYRA SNAGNDDGSS
1060 1070 1080 1090 1100
PTNIMNGKML EDRSDMIYYN TMNVGGRNWM IALRPSRKFT NKHYTFYPYA
1110 1120 1130 1140 1150
IGGVCMLLSA LVSFWFAVNT KHNIKLSATN EDLHKEIYNR KLAEKALAES
1160 1170 1180 1190 1200
QERLELAMEG SEDAVWDWKV NTGELHISSR WFQILKAHDT SYQSRTLYEE
1210 1220 1230 1240 1250
LKSSSTNNLN FKGDSKNGGS NNGTFNLFKN GKVDSSSPQS ITNVNTTNGG
1260 1270 1280 1290 1300
GGGELRKSNS GYLYNDELFS PIILEEMVSS PNTHQLAIWN MKFLAELIHP
1310 1320 1330 1340 1350
DDKQKFISEI KKTITRETSI MEIECRMRKK YGGYLYIIMR GKVVSNETSF
1360 1370 1380 1390 1400
KDNSLRMAGT LRDMTSRKDM QRLILEKEAA EEANKAKSAF VATVSHEVRT
1410 1420 1430 1440 1450
PLSGVIGVSD LLLETNLSEE QRDYVQTIQK SSQALLTIIN DILDYSKLES
1460 1470 1480 1490 1500
RQLKMETLPF SIIETCQAVI HMLSVAANDD VDILLRVPPN VPRIIFGDAM
1510 1520 1530 1540 1550
RMRQVLLNLL SNAIKFTSRG HVLTDISVDD SIPPTNTEEE IIHLCITIED
1560 1570 1580 1590 1600
TGIGIPQSLF DSIFEPFSQA DNSTTRKYGG TGLGLSITKR LIEEVMGGTI
1610 1620 1630 1640 1650
QVSSIVGQGS KFKCIIPFLL PNTSPSDLNL ISPSSLPKPF INRSPKSTYS
1660 1670 1680 1690 1700
FTDKKNSVPS TPIPSGDILI NKVCLLICRD TVTELVFKEQ LEWLGMIVKQ
1710 1720 1730 1740 1750
VPRNVIDSIK NTILNNNNNN NNNNNNNNNN SNNSSSIISP SSLDYSDENE
1760 1770 1780 1790 1800
HLDLVLIDLE ILTEHLKIPS NVPIIFITPT KFNISKHNGI LNKWITKSPN
1810 1820 1830 1840 1850
QRVELIRRPA ITDKLIPIIS KCIKSQVQFT SGSSQLQSQQ ANLQQQLLHQ
1860 1870 1880 1890 1900
QLCNNGQTLN NNYNSGGIGG GGGGGGSNTM NGSSGNLSNN NNFGQTPLSS
1910 1920 1930 1940 1950
GLVLLVHTGR TPPLFNNNGN SIIPPLELAV DHHGNQQQQL YQQQQQQQNN
1960 1970 1980 1990 2000
SSGNFQQFYQ QQNNNSNNSF TPTLPNENSN NSIMNNSLNN NNTTPSNVTP
2010 2020 2030 2040 2050
TLFTSSPLDL QGRDTPVLQP PAYRKKALIV EDNELNRKVL AQLFKKIDWT
2060 2070 2080 2090 2100
ISFAENGREA LKEITGERCF DIVFMDCQMP VLDGFQTTKI IRSKERENNW
2110 2120 2130 2140 2150
KRMNIVALSA GSSSSFVQDC LDSGMDSFMG KPITLATLKD ALAKWGGYNN
Length:2,150
Mass (Da):239,636
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1FDA618EE9B3DBCA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1319S → A in AAC47300 (PubMed:8670894).Curated1
Sequence conflicti1509L → R in AAC47300 (PubMed:8670894).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U42597 mRNA Translation: AAC47300.1
AAFI02000040 Genomic DNA Translation: EAL66777.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S71629

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL66777; EAL66777; DDB_G0280961

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0280961

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U42597 mRNA Translation: AAC47300.1
AAFI02000040 Genomic DNA Translation: EAL66777.1
PIRiS71629

3D structure databases

SMRiQ54U87
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0215354

Proteomic databases

PaxDbiQ54U87
PRIDEiQ54U87

Genome annotation databases

EnsemblProtistsiEAL66777; EAL66777; DDB_G0280961
KEGGiddi:DDB_G0280961

Organism-specific databases

dictyBaseiDDB_G0280961, dhkA

Phylogenomic databases

eggNOGiKOG0519, Eukaryota
HOGENOMiCLU_231770_0_0_1
InParanoidiQ54U87
OMAiSIMEIEC

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q54U87

Family and domain databases

CDDicd00082, HisKA, 1 hit
cd00130, PAS, 1 hit
cd00156, REC, 1 hit
Gene3Di3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR006189, CHASE_dom
IPR011006, CheY-like_superfamily
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR001610, PAC
IPR000014, PAS
IPR035965, PAS-like_dom_sf
IPR013655, PAS_fold_3
IPR004358, Sig_transdc_His_kin-like_C
IPR001789, Sig_transdc_resp-reg_receiver
PfamiView protein in Pfam
PF03924, CHASE, 1 hit
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF08447, PAS_3, 1 hit
PF00072, Response_reg, 1 hit
PRINTSiPR00344, BCTRLSENSOR
SMARTiView protein in SMART
SM01079, CHASE, 1 hit
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00086, PAC, 1 hit
SM00448, REC, 1 hit
SUPFAMiSSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 1 hit
SSF55785, SSF55785, 1 hit
SSF55874, SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS50839, CHASE, 1 hit
PS50109, HIS_KIN, 1 hit
PS50110, RESPONSE_REGULATORY, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDHKA_DICDI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q54U87
Secondary accession number(s): Q23863
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: October 7, 2020
This is version 102 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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