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Entry version 105 (07 Apr 2021)
Sequence version 1 (24 May 2005)
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Protein

Hybrid signal transduction histidine kinase L

Gene

dhkL

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. EC:2.7.13.3

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transducer, Transferase
Biological processTwo-component regulatory system
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Hybrid signal transduction histidine kinase L (EC:2.7.13.3)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dhkL
ORF Names:DDB_G0282927
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyosteliaDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0282927, dhkL

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003283691 – 1709Hybrid signal transduction histidine kinase LAdd BLAST1709

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei840Phosphohistidine; by autocatalysisPROSITE-ProRule annotation1
Modified residuei13664-aspartylphosphatePROSITE-ProRule annotation1
Modified residuei16224-aspartylphosphatePROSITE-ProRule annotation1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Activation probably requires transfer of a phosphate group between a histidine in the kinase core (transmitter) domain and an aspartate of the receiver domain.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q54RP6

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0191389

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q54RP6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini700 – 771PASPROSITE-ProRule annotationAdd BLAST72
Domaini770 – 822PACAdd BLAST53
Domaini837 – 1059Histidine kinasePROSITE-ProRule annotationAdd BLAST223
Domaini1312 – 1492Response regulatory 1PROSITE-ProRule annotationAdd BLAST181
Domaini1570 – 1692Response regulatory 2PROSITE-ProRule annotationAdd BLAST123

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi53 – 88Poly-AsnAdd BLAST36
Compositional biasi106 – 112Poly-Thr7
Compositional biasi113 – 148Poly-AsnAdd BLAST36
Compositional biasi212 – 218Poly-Ser7
Compositional biasi424 – 430Poly-Ser7
Compositional biasi433 – 440Poly-Asn8
Compositional biasi443 – 449Poly-Asn7
Compositional biasi494 – 499Poly-Asn6
Compositional biasi500 – 523Poly-GlnAdd BLAST24
Compositional biasi539 – 562Poly-GlnAdd BLAST24
Compositional biasi1076 – 1089Poly-GlnAdd BLAST14
Compositional biasi1101 – 1144Poly-GlnAdd BLAST44
Compositional biasi1147 – 1154Poly-Gln8
Compositional biasi1155 – 1158Poly-His4
Compositional biasi1164 – 1168Poly-Gln5
Compositional biasi1180 – 1195Poly-GlnAdd BLAST16
Compositional biasi1223 – 1228Poly-Asn6
Compositional biasi1393 – 1408Poly-GlnAdd BLAST16
Compositional biasi1425 – 1433Poly-Asn9
Compositional biasi1499 – 1510Poly-AsnAdd BLAST12
Compositional biasi1515 – 1521Poly-Gly7

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Atypical domain architecture: contains 2 receiver domains.

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0519, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_240641_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q54RP6

Identification of Orthologs from Complete Genome Data

More...
OMAi
SWTIGES

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00082, HisKA, 1 hit
cd00130, PAS, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.565.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011006, CheY-like_superfamily
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR000014, PAS
IPR035965, PAS-like_dom_sf
IPR004358, Sig_transdc_His_kin-like_C
IPR001789, Sig_transdc_resp-reg_receiver

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF13426, PAS_9, 1 hit
PF00072, Response_reg, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00344, BCTRLSENSOR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00091, PAS, 1 hit
SM00448, REC, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 3 hits
SSF55785, SSF55785, 1 hit
SSF55874, SSF55874, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00229, sensory_box, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50109, HIS_KIN, 1 hit
PS50112, PAS, 1 hit
PS50110, RESPONSE_REGULATORY, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q54RP6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGSKRDIIE NSNNGNNKGV VIEELGETYY TNSKPSTSAD CKYFRDSFEF
60 70 80 90 100
GSNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNEE KSNNETEKTL
110 120 130 140 150
ESNGDTTTTT TTNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNTNSS
160 170 180 190 200
NDIYMNSPSS TLSSPGNAGN NLPIGCTKPN VPKSPYSPSP PHLYKSNSTS
210 220 230 240 250
YLKSSFFSGN GSSSSSSSTT TTNINSNNSN TNTYSTSTNV KKNNSNTNSN
260 270 280 290 300
TNNNTNGNTN TNSNSNKKNI NSNSSDNIII NDTADIMNRR RDRFKSFSWT
310 320 330 340 350
IGESNSNSKF SELSMISSKC KSIKSEFTPL FETLTVFDES DKIRHSLIQN
360 370 380 390 400
HYKTLLIQNP ASPNRTLLTN LLQRRGHNLT TCPIDINHVL QLLQKESFSL
410 420 430 440 450
FIFDPNESII NNTSNSISSN EPISLSSSSS YYNNNNSNNN SVNNNNNNNS
460 470 480 490 500
GNSTNNNSPS SHTPNSPMIF QPIVSNICSN SGGSGNNSPH HIDNNNNSNQ
510 520 530 540 550
QQQQQQQQQQ QQQQHQHQQQ QQQSSSTTAT TNNSCTLNQQ QQQQQQQQQQ
560 570 580 590 600
QQQQQQQQQQ SQPTTPTQST QSPTTSISFS KKKNLTINTS FKTSPMSSPK
610 620 630 640 650
SFNKPSQSPQ NIFNNFSNTY NPNNIEFCKI LKSKLTEFET VIVLTESTDP
660 670 680 690 700
SEFCQYIDAG ATDYIPQPIS PILLDLRLTT CQKLVNNNLH LKKAESLKDA
710 720 730 740 750
TRKMVTCIEN SPDCVEIWDP SGHIQYLNLA FSEMTGFARW ELLGKEFSNL
760 770 780 790 800
IDNTEIIPNM WATLTDKKTW NGFIRTRHNN NTLIYFEASI SPVLDQFQQI
810 820 830 840 850
LYYNCTKRDV TQKRIDEESK TLEQNKIIEK SRLRLSMMSH DIRTPMSNII
860 870 880 890 900
GMADLLLDTS LSQHQHHYLE IIKNSSNTLL TIINDILDIS KIEAGKLDID
910 920 930 940 950
YESFDFNATV SQVVESMAQR VQSKGLELLS YVDPKIPNIL IGPSSRLNQI
960 970 980 990 1000
LTNLLGNSLK FTDKGEISIC CLLNDETDSE YEIKVDVRDT GIGIKKEALP
1010 1020 1030 1040 1050
LLFKAFTQAE GTITRQYGGS GLGLAICKEL VHLAFNGEIS VESQYGHGST
1060 1070 1080 1090 1100
FTCILKFKKF LPSDSQNLLP ASSPLQQQQQ QQQHQQQTQF HQHQQQTQFH
1110 1120 1130 1140 1150
QHQQQQLQHQ QHQQHQQLQQ QQQQQQQLQQ QLQQHQQHQL QQRQHHQQQL
1160 1170 1180 1190 1200
QQQQHHHHQQ VHLQQQQQHE HDAQHNQHIQ QQQQQQQQQQ QQQQQHEHNN
1210 1220 1230 1240 1250
NGHHNSHGHN HHGSHHNHNH QHNNNNNNIT INKLQHQEKK QKSNEQQLES
1260 1270 1280 1290 1300
ITENSFSPIV EPMVISDPDT PEALNISQSP SPQSIHNGTT INQQPTSPLN
1310 1320 1330 1340 1350
TLGSKFDFSG AKMLFIERND TSRGNLFKQL LAWNIQLELV EDGESGFRKW
1360 1370 1380 1390 1400
KQSIESNSPY SIIIMDLNTP GVDGASLPMR IKKELELMQQ HLQQQQEQEQ
1410 1420 1430 1440 1450
QQQQEQQQSE LQKQPDVENK NSSQNNDNNN NNNKSNSSGG NQCIYRSPII
1460 1470 1480 1490 1500
MLMPIQFLNS QLEDNLKDAG VCAILSKPIR MSQLADVFMM YLGPNSEHNN
1510 1520 1530 1540 1550
NNNYNNNNGN GYLNGGGGGG GSVNGTGNGT LQVGMSNDGG NGCGVVSFWN
1560 1570 1580 1590 1600
KQRRASAEEQ EQDPSKLLGK VLVVDDNHIN IQILSKMLQT VGCEVDSVLS
1610 1620 1630 1640 1650
GADALAKINQ SSGDSYDAIF LDIQMPDMDG FQVSRKIRER EKKFSLPRVA
1660 1670 1680 1690 1700
IIATTANVFK EDQLKCFDAG MDDFISKPIK RAEIKEIIKK YGKNGNHQSG

SAYSLYKLS
Length:1,709
Mass (Da):192,704
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD64A78BBE43ABA12
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti2E → Q in AAK54092 (Ref. 1) Curated1
Sequence conflicti6 – 7RD → TH in AAK54092 (Ref. 1) Curated2
Sequence conflicti538N → Y in AAK54092 (Ref. 1) Curated1
Sequence conflicti644L → W in AAK54092 (Ref. 1) Curated1
Sequence conflicti681C → G in AAK54092 (Ref. 1) Curated1
Sequence conflicti684L → V in AAK54092 (Ref. 1) Curated1
Sequence conflicti687N → T in AAK54092 (Ref. 1) Curated1
Sequence conflicti694A → G in AAK54092 (Ref. 1) Curated1
Sequence conflicti701 – 702TR → PG in AAK54092 (Ref. 1) Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF362373 Genomic DNA Translation: AAK54092.2
AAFI02000049 Genomic DNA Translation: EAL65907.1
AF258796 Genomic DNA Translation: AAG00916.1

NCBI Reference Sequences

More...
RefSeqi
XP_639305.1, XM_634213.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL65907; EAL65907; DDB_G0282927

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8623876

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0282927

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF362373 Genomic DNA Translation: AAK54092.2
AAFI02000049 Genomic DNA Translation: EAL65907.1
AF258796 Genomic DNA Translation: AAG00916.1
RefSeqiXP_639305.1, XM_634213.1

3D structure databases

SMRiQ54RP6
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0191389

Proteomic databases

PaxDbiQ54RP6

Genome annotation databases

EnsemblProtistsiEAL65907; EAL65907; DDB_G0282927
GeneIDi8623876
KEGGiddi:DDB_G0282927

Organism-specific databases

dictyBaseiDDB_G0282927, dhkL

Phylogenomic databases

eggNOGiKOG0519, Eukaryota
HOGENOMiCLU_240641_0_0_1
InParanoidiQ54RP6
OMAiSWTIGES

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q54RP6

Family and domain databases

CDDicd00082, HisKA, 1 hit
cd00130, PAS, 1 hit
Gene3Di3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR011006, CheY-like_superfamily
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR000014, PAS
IPR035965, PAS-like_dom_sf
IPR004358, Sig_transdc_His_kin-like_C
IPR001789, Sig_transdc_resp-reg_receiver
PfamiView protein in Pfam
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF13426, PAS_9, 1 hit
PF00072, Response_reg, 1 hit
PRINTSiPR00344, BCTRLSENSOR
SMARTiView protein in SMART
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00091, PAS, 1 hit
SM00448, REC, 2 hits
SUPFAMiSSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 3 hits
SSF55785, SSF55785, 1 hit
SSF55874, SSF55874, 1 hit
TIGRFAMsiTIGR00229, sensory_box, 1 hit
PROSITEiView protein in PROSITE
PS50109, HIS_KIN, 1 hit
PS50112, PAS, 1 hit
PS50110, RESPONSE_REGULATORY, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDHKL_DICDI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q54RP6
Secondary accession number(s): Q95PH5, Q9GTU0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: April 7, 2021
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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