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Entry version 98 (26 Feb 2020)
Sequence version 1 (24 May 2005)
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Protein

DNA polymerase epsilon catalytic subunit A

Gene

pole

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

DNA polymerase II participates in chromosomal DNA replication.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi2225ZincBy similarity1
Metal bindingi2228ZincBy similarity1
Metal bindingi2285ZincBy similarity1
Metal bindingi2288ZincBy similarity1
Metal bindingi2319Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi2322Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi2334Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi2337Iron-sulfur (4Fe-4S)By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri2225 – 2288CysA-typeBy similarityAdd BLAST64

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase
Biological processDNA replication
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DDI-110314 Recognition of DNA damage by PCNA-containing replication complex
R-DDI-174430 Telomere C-strand synthesis initiation
R-DDI-5651801 PCNA-Dependent Long Patch Base Excision Repair
R-DDI-5656169 Termination of translesion DNA synthesis
R-DDI-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER
R-DDI-6782135 Dual incision in TC-NER
R-DDI-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER
R-DDI-68952 DNA replication initiation
R-DDI-68962 Activation of the pre-replicative complex

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA polymerase epsilon catalytic subunit A (EC:2.7.7.7By similarity)
Alternative name(s):
DNA polymerase II subunit A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pole
Synonyms:pol2
ORF Names:DDB_G0283189
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyosteliaDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0283189

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003283491 – 2380DNA polymerase epsilon catalytic subunit AAdd BLAST2380

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q54RD4

PRoteomics IDEntifications database

More...
PRIDEi
Q54RD4

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Consists of three subunits: pole, pole2 and pole3.

Curated

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0216320

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q54RD4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi2319 – 2337CysB motifBy similarityAdd BLAST19

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi174 – 179Poly-Asn6
Compositional biasi182 – 195Poly-AsnAdd BLAST14
Compositional biasi203 – 207Poly-Asn5
Compositional biasi1323 – 1327Poly-Ser5
Compositional biasi1966 – 1973Poly-Gln8
Compositional biasi1977 – 1983Poly-Asp7
Compositional biasi2026 – 2029Poly-Ile4
Compositional biasi2064 – 2067Poly-Ser4
Compositional biasi2075 – 2079Poly-Thr5
Compositional biasi2110 – 2114Poly-Ser5
Compositional biasi2115 – 2119Poly-Thr5

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The CysA-type zinc finger is required for PCNA-binding.By similarity
The CysB motif binds 1 4Fe-4S cluster and is required for the formation of polymerase complexes.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA polymerase type-B family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri2225 – 2288CysA-typeBy similarityAdd BLAST64

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1798 Eukaryota
COG0417 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000556_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q54RD4

KEGG Orthology (KO)

More...
KOi
K02324

Identification of Orthologs from Complete Genome Data

More...
OMAi
VYDLDMK

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q54RD4

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.132.60, 1 hit
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR042087 DNA_pol_B_C
IPR013697 DNA_pol_e_suA_C
IPR029703 POL2
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10670 PTHR10670, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08490 DUF1744, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01159 DUF1744, 1 hit
SM00486 POLBc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098 SSF53098, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q54RD4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQKWNENKK NKDEKDENDK YVGFKNYEKE GWLLNMQPGS SKDGLDIEKA
60 70 80 90 100
SLELFFIQDD ATSFRVWIPY NPYFYIYVKE GHQSEVESYL KSTYEKDIAG
110 120 130 140 150
IDIMDKEDLD LENHLSGLKR KYLKIRFHNV STLLSVRNDL FPIIKRNKQK
160 170 180 190 200
SNTSEAYEDE SLNKILNSYY NKGNNNNNNH QNYNNNNNQN NNNFNKELNK
210 220 230 240 250
DDNNNNNSKL NKQATEYILD IREYDVPYYV RAAIDLNIRV GLWYTVIKNG
260 270 280 290 300
RLTTVNELTT RVDRPDPKVL AYDIETTKLP LKFPDSSIDS IMMISYMLDK
310 320 330 340 350
QGYLIVNREI VSEDIKDFEY TPKPEYYGPF TVFNEPDEKS VLERFFSEIK
360 370 380 390 400
REKPHIFVSY NGDMFDWPFV ESRAEYHGLS MFHQIGFRND NGEYRSKINP
410 420 430 440 450
HMDAFCWVKR DSYLPHGSHG LKAVTREKLR YDPLELDPEL MLKSAQEDPE
460 470 480 490 500
TLANYSVSDA VATYYLYMNY VHPFIFSLCT IIPMNPDDVL RKGSGTLCEA
510 520 530 540 550
LLMTQAFKAD VIFPNKHKDD INSMYKGHLL ESETYVGGHV ECLESGVFRS
560 570 580 590 600
DIPTNFSLDP ASIEKHMGNI DQVLKFALKE GGIPLDTVSN YQEVKEDVLK
610 620 630 640 650
KFTLLKENPK QQSHPLIYHL DVSAMYPNII LTNKLQPTAV VNDEVCATCV
660 670 680 690 700
YNKPESQCQR TLDWQWRGDY SPSNQSEYRL ILQQLESEKF GDGDERKSFL
710 720 730 740 750
SLSEEKRNEL LRKRLKEYSR KVYRKTHQIT QEIRSDTICM RENSFYVDTV
760 770 780 790 800
RLFRDRRYVF KNHHRDWKIK YDQAMQESGG TNSVAVVAAQ GMVVLYESLQ
810 820 830 840 850
LAHKCILNSF YGYVMRKGAR WYSMQMAGIV THTGSNIIKE AREVVEQMGR
860 870 880 890 900
PLEIDTDGIW CILPSHFPEN YTLKSASTGK KVTFSYICEM LNEKVAKSFT
910 920 930 940 950
NHQYQDYNAE TNTYTIRDEC SILFECDGPY RCMLIPTSKE KDVKLKKRYA
960 970 980 990 1000
VFNREGRICE LKGFEIKRRG ELKLIKLFQS EVFKEFLGGD SLEGCYQSVG
1010 1020 1030 1040 1050
AVANRWLDIL DSHAENYEEK DLIELITESS NMSRKLEEYG TQKSSAISTA
1060 1070 1080 1090 1100
KKLAEFLGDD MIKDKGLSCQ YIISNKPAGS PITERALPVA IFDADFETRC
1110 1120 1130 1140 1150
HYLRRWTKSP SGDLDIRELI DWDYYRQRLS GVIQKIITIP AALQNVTNPV
1160 1170 1180 1190 1200
PRVIHPDWIL KEIRRNEDGR QQTSITSFFE KTEDNDQDND NDNDNDNDND
1210 1220 1230 1240 1250
NDNSKPQQTD DIENMFSSRF KDLPAFNPKV TKFKRSKQSS SDVSSLLIKK
1260 1270 1280 1290 1300
SKSSIETFTN EQEKQIMETK TPSIDKDFQG WLSISKKKWK IQRLLKKRRQ
1310 1320 1330 1340 1350
RLGGSLFDSD SFRIGSKLTN RESSSSSFFK SQSDIIKKGY WNIISIEPIY
1360 1370 1380 1390 1400
GGEPGIYQMW SLIEDQLIPI KVDIGRVFYL NSIDTDPYED AQKNTNVIPP
1410 1420 1430 1440 1450
RGKQRFNVFS VTMSESQFLE QSKELNTLFT NPMIEGVYET KVPLDIKAII
1460 1470 1480 1490 1500
QCGCVATLSR VSPFFTKIVN SNTRFSLEDI ASKPDKQFHY LAEHNFNQLF
1510 1520 1530 1540 1550
LYHNSRDGKD GYFVLFNMNT QQCSVIFSNP YMAANKIDAR VLNSIKEKLP
1560 1570 1580 1590 1600
EITFTMDQKS SMSLAKKEIG SLIMEYQRKG LPTIILLQVP NAIGILEQIP
1610 1620 1630 1640 1650
ILREFPRVPV PYHDNDSMYS PFNWDVHSLK PLPLRLMDAP KLWVYYANMS
1660 1670 1680 1690 1700
RYANIPIGNI PTDNASFMCD ILYARSLVEQ KHLLWMSDSN FPDLGGSEED
1710 1720 1730 1740 1750
DAKFYEELNN VEINNSDCYN QVCFELDIEN LATNTILESI HLAEIEGILG
1760 1770 1780 1790 1800
NELGDESNVA MFDDIKNTSN NSNTKNGANQ NTTNDTTSSF DKLSITNKFR
1810 1820 1830 1840 1850
SAINHQISGC EKEFNILRNL VSKWKLDLVS GSNSKRNEIS SRYSNYLLLH
1860 1870 1880 1890 1900
FYRWISSTNS KLYDPILYRT LHQLMKKVFI QLIFEFKKLG SKIVYANFNK
1910 1920 1930 1940 1950
IIICSQKDSI EDARSYCNYI LAVIKKKELF SWINFKQTNY YHNLLWLNNS
1960 1970 1980 1990 2000
NYSGILYFNP LINKNQQQQQ QQQDNADDDD DDDVSENEEE QQQNKNKKLK
2010 2020 2030 2040 2050
KIKNGKIITN WNIAEFLPPQ IQTSFIIIIS DYIYKLHTER DELNRIQKEQ
2060 2070 2080 2090 2100
QQRYLLKQKI STTSSSSNND STAATTTTTK DTINEPTKPD LRKSSTWNEE
2110 2120 2130 2140 2150
EDEDISIPPS SSSSTTTTTS KTKKATSKFD LLIDVNRIFT LLDHFQVNQS
2160 2170 2180 2190 2200
SLEFPQLPGG YLKLNNPPLE FIKFVCHVLS IDKSISSRVS RLRMKLMTSM
2210 2220 2230 2240 2250
KVREFSDEAK FKDPCVSFTL PDVICSSCHS CRDIDLLRNT NTTSISSRLS
2260 2270 2280 2290 2300
SQQKSNNNDS DDSDDDNEEN EGDDDNIIRV PELSCIQCKG HYSKNTIESQ
2310 2320 2330 2340 2350
LVEIIQRRSL SYQLQDLRCS KCNDVKSDNL GDICPQCSGQ WECTQSNNLF
2360 2370 2380
SKDLIIFKSI AEYHNFEWLG ETVDSLSKFI
Length:2,380
Mass (Da):275,442
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB4DC5FAA0542994B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000051 Genomic DNA Translation: EAL65833.1

NCBI Reference Sequences

More...
RefSeqi
XP_639211.1, XM_634119.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL65833; EAL65833; DDB_G0283189

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8623984

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0283189

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000051 Genomic DNA Translation: EAL65833.1
RefSeqiXP_639211.1, XM_634119.1

3D structure databases

SMRiQ54RD4
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0216320

Proteomic databases

PaxDbiQ54RD4
PRIDEiQ54RD4

Genome annotation databases

EnsemblProtistsiEAL65833; EAL65833; DDB_G0283189
GeneIDi8623984
KEGGiddi:DDB_G0283189

Organism-specific databases

dictyBaseiDDB_G0283189

Phylogenomic databases

eggNOGiKOG1798 Eukaryota
COG0417 LUCA
HOGENOMiCLU_000556_0_1_1
InParanoidiQ54RD4
KOiK02324
OMAiVYDLDMK
PhylomeDBiQ54RD4

Enzyme and pathway databases

ReactomeiR-DDI-110314 Recognition of DNA damage by PCNA-containing replication complex
R-DDI-174430 Telomere C-strand synthesis initiation
R-DDI-5651801 PCNA-Dependent Long Patch Base Excision Repair
R-DDI-5656169 Termination of translesion DNA synthesis
R-DDI-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER
R-DDI-6782135 Dual incision in TC-NER
R-DDI-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER
R-DDI-68952 DNA replication initiation
R-DDI-68962 Activation of the pre-replicative complex

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q54RD4

Family and domain databases

Gene3Di1.10.132.60, 1 hit
3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR042087 DNA_pol_B_C
IPR013697 DNA_pol_e_suA_C
IPR029703 POL2
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PANTHERiPTHR10670 PTHR10670, 1 hit
PfamiView protein in Pfam
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08490 DUF1744, 1 hit
SMARTiView protein in SMART
SM01159 DUF1744, 1 hit
SM00486 POLBc, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDPOE1_DICDI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q54RD4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: February 26, 2020
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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