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Protein

Mitochondrial substrate carrier family protein M

Gene

mcfM

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports folate across the inner membranes of mitochondria (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial substrate carrier family protein M
Alternative name(s):
Solute carrier family 25 member 32 homolog
Gene namesi
Name:mcfM
Synonyms:slc25a32
ORF Names:DDB_G0283751
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0283751 mcfM

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 10Mitochondrial intermembraneBy similarity10
Transmembranei11 – 31Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini32 – 72Mitochondrial matrixBy similarityAdd BLAST41
Transmembranei73 – 89Helical; Name=2Sequence analysisAdd BLAST17
Topological domaini90 – 113Mitochondrial intermembraneBy similarityAdd BLAST24
Transmembranei114 – 134Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini135 – 163Mitochondrial matrixBy similarityAdd BLAST29
Transmembranei164 – 184Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini185 – 211Mitochondrial intermembraneBy similarityAdd BLAST27
Transmembranei212 – 232Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini233 – 278Mitochondrial matrixBy similarityAdd BLAST46
Transmembranei279 – 296Helical; Name=6Sequence analysisAdd BLAST18
Topological domaini297 – 306Mitochondrial intermembraneBy similarity10

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003855331 – 306Mitochondrial substrate carrier family protein MAdd BLAST306

Proteomic databases

PaxDbiQ54QN2
PRIDEiQ54QN2

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0237607

Structurei

3D structure databases

ProteinModelPortaliQ54QN2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati5 – 98Solcar 1Add BLAST94
Repeati108 – 195Solcar 2Add BLAST88
Repeati207 – 299Solcar 3Add BLAST93

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0764 Eukaryota
ENOG410XPAJ LUCA
InParanoidiQ54QN2
KOiK15115
OMAiLRPKYKG
PhylomeDBiQ54QN2

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Q54QN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYILNNNVE GTSALLGSTV ATAFLQPFDF LKIRLQGSGF ASGGDLNKFK
60 70 80 90 100
RVGVIDTCKN VLKNEGIKQF WRGSSPTIVA SGIAWGTYMH FYEAYKNILK
110 120 130 140 150
SKYNVTQLNT FDHFICAVGA SATQVFITNP IFLIKTRMQL QTPGSANYYT
160 170 180 190 200
GIFDGIKKTV KVEGFKGLYK GVIPSLWLTF HGGIQMSSYE HIKFYFSSNS
210 220 230 240 250
GKSLDSLNAS EIFIASSISK FLASTILYPF QVVKTRLQDE RNIPNQNNVR
260 270 280 290 300
VYNGTKDVIF KILKNEGIIG FYRGLVPNTL KVIPNTSITL LLYEEIKKSF

NYIINE
Length:306
Mass (Da):34,343
Last modified:May 24, 2005 - v1
Checksum:iB728874AA7D85146
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000056 Genomic DNA Translation: EAL65642.1
RefSeqiXP_638991.1, XM_633899.1

Genome annotation databases

EnsemblProtistsiEAL65642; EAL65642; DDB_G0283751
GeneIDi8624237
KEGGiddi:DDB_G0283751

Similar proteinsi

Entry informationi

Entry nameiMCFM_DICDI
AccessioniPrimary (citable) accession number: Q54QN2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 13, 2009
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

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