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Entry version 70 (02 Dec 2020)
Sequence version 1 (24 May 2005)
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Protein

SUN domain-containing protein 2

Gene

sun2

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SUN domain-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sun2
ORF Names:DDB_G0285925
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyosteliaDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0285925, sunB

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei914 – 934HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000038926226 – 1278SUN domain-containing protein 2Add BLAST1253

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi47N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi56N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi166N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi293N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi356N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi370N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi386N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi391N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi405N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi558N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi669N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi832N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi941N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi969N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi983N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi994N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi999N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1005N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1028N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1036N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1041N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1049N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1107N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1138N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1147N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1214N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1227N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1241N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1267N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q54MI3

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0304575

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q54MI3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini501 – 658SUNPROSITE-ProRule annotationAdd BLAST158

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili177 – 349Sequence analysisAdd BLAST173
Coiled coili464 – 509Sequence analysisAdd BLAST46
Coiled coili883 – 914Sequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi26 – 31Poly-Gln6
Compositional biasi76 – 110Poly-AsnAdd BLAST35
Compositional biasi160 – 164Poly-Thr5
Compositional biasi302 – 319Poly-GlnAdd BLAST18
Compositional biasi325 – 342Poly-GlnAdd BLAST18
Compositional biasi345 – 348Poly-Gln4
Compositional biasi416 – 421Poly-Asn6
Compositional biasi466 – 507Poly-GlnAdd BLAST42
Compositional biasi703 – 710Poly-Ser8
Compositional biasi752 – 780Poly-AsnAdd BLAST29
Compositional biasi797 – 807Poly-SerAdd BLAST11
Compositional biasi935 – 940Poly-Ser6
Compositional biasi972 – 979Poly-Gly8
Compositional biasi1014 – 1021Poly-Asn8
Compositional biasi1024 – 1037Poly-AsnAdd BLAST14
Compositional biasi1097 – 1139Poly-AsnAdd BLAST43
Compositional biasi1142 – 1154Poly-AsnAdd BLAST13
Compositional biasi1223 – 1241Poly-AsnAdd BLAST19
Compositional biasi1253 – 1256Poly-Ser4

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The SUN domain may play a role in the nuclear anchoring.By similarity

Keywords - Domaini

Coiled coil, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1396, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_263367_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q54MI3

Identification of Orthologs from Complete Genome Data

More...
OMAi
PDKFNYA

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008979, Galactose-bd-like_sf
IPR012919, SUN_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07738, Sad1_UNC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785, SSF49785, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51469, SUN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q54MI3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIINKKYILF ILLLLFITSC TIVFSQQQQQ QTEQSEQTEQ AINNDVNNSI
60 70 80 90 100
NDIFENDSSK QLRQPQQQHT IVDDGNNNNN NNNNNNNNNN NNNNNNNNNN
110 120 130 140 150
NNNNNNNNNN PIDNKDILGL KKLALLKQFE EQKSKSENDI NNDIVILNLE
160 170 180 190 200
NDNPNQIIET TTTTLNNSND NKNNIIDDNQ DEKLNENIKE DKNEIKNEIK
210 220 230 240 250
NENQEKDKGI IDVEKDENQP NIEEKGKEKQ NLLEKGIENE NQNENQIQIE
260 270 280 290 300
KEKEIEIEIE KEKEKENKEL IEESKTEKDN QQKENKENTN EINVTVVEEP
310 320 330 340 350
EQPQPQQQNQ QEQQEQQQQE HKEEQQQQEQ QQQEQQTQQE QQTHQQQQEH
360 370 380 390 400
QETQKNSSEE TKTQSPIQVN TTDVNNEIEL KNEGDNNSQL NDSSIPITSP
410 420 430 440 450
LTNDNDTLKT TKEDSNNNNK NEVINNQTPL IDEKNHQHNY EGNNRNGDDV
460 470 480 490 500
SIISNIPKTN KAPETQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ
510 520 530 540 550
QQQQQQQHVV LTPNDLPDKF NYASSECGAN VLQTNKEAWE VSSILASSRD
560 570 580 590 600
RYLLNECNKS QWFVVELCEE IGVQIIELAN FEFFSSMFKD FIVLGSNRYP
610 620 630 640 650
AQSWHYLGQF TAENSRKQQY FVLKEKAWYK YLKVKILSHY GDQLYCPISS
660 670 680 690 700
FKVYGSTMVD DLKNQVDINI SELEKFQRDL SSIPYPMEIG SDTSYSTTTS
710 720 730 740 750
TTSSSSTSSS YPSSKTKSSN SEYPSWERIQ SFSEKLRKNV EQQLIQPPSV
760 770 780 790 800
LNTNDNNNNN NNNNNNNNNN NNNNNNNNNN EEQFIYYETN GNGGPPSTST
810 820 830 840 850
STSSSSSQNH QARTPQSVFK TLADKIKAIE FNQSIGNKFM EKLERYYSEE
860 870 880 890 900
IKNLKFDVSE FLNDIIKLGN SLDEKLKDHR KYDDNKFKET SKEIKILKEK
910 920 930 940 950
IEKLEEQKSA DRNFYLVVTL VSLLIGLLLK PLFTSSSSSS NKSYPNSMPN
960 970 980 990 1000
SPTYLNSGSN NYNNNGIINS SGGSGGGGGN LQNSSFIGIN GQLNFSDDNI
1010 1020 1030 1040 1050
SAFLNSSCSN FGLNNNNNNN NGINNNNNNS NSNSNNNSIN NGSININSNN
1060 1070 1080 1090 1100
SLQQRIHHNK YIHQRRNSSP LVGVQLESFF SPNAIPPTIP IVPQDDNNIN
1110 1120 1130 1140 1150
YNYNNNNNTN NINNNYNYNN NNNNNNNNNN NNNNNNNNNS DNYNNNNNSN
1160 1170 1180 1190 1200
NNVNSPSSPT PSSIILSPKF ITSIPKNINY YNNGGSGSHL KNRFSRQASE
1210 1220 1230 1240 1250
SVLSQNHYQI NHQNHSLNGV TTNINNNNSN SNGNSNGNSN NMTNGLPPVS
1260 1270
MPSSSSHDNL LLHRGNNQSK KYKRRSHL
Length:1,278
Mass (Da):146,049
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2F1D31084CDF0FDE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000082 Genomic DNA Translation: EAL64497.1

NCBI Reference Sequences

More...
RefSeqi
XP_638007.1, XM_632915.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL64497; EAL64497; DDB_G0285925

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8625358

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0285925

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000082 Genomic DNA Translation: EAL64497.1
RefSeqiXP_638007.1, XM_632915.1

3D structure databases

SMRiQ54MI3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0304575

Proteomic databases

PaxDbiQ54MI3

Genome annotation databases

EnsemblProtistsiEAL64497; EAL64497; DDB_G0285925
GeneIDi8625358
KEGGiddi:DDB_G0285925

Organism-specific databases

dictyBaseiDDB_G0285925, sunB

Phylogenomic databases

eggNOGiKOG1396, Eukaryota
HOGENOMiCLU_263367_0_0_1
InParanoidiQ54MI3
OMAiPDKFNYA

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q54MI3

Family and domain databases

InterProiView protein in InterPro
IPR008979, Galactose-bd-like_sf
IPR012919, SUN_dom
PfamiView protein in Pfam
PF07738, Sad1_UNC, 1 hit
SUPFAMiSSF49785, SSF49785, 1 hit
PROSITEiView protein in PROSITE
PS51469, SUN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSUN2_DICDI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q54MI3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: May 24, 2005
Last modified: December 2, 2020
This is version 70 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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