UniProtKB - Q54LH5 (INT4_DICDI)
Protein
Integrator complex subunit 4 homolog
Gene
ints4
Organism
Dictyostelium discoideum (Slime mold)
Status
Functioni
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.By similarity
GO - Biological processi
- snRNA processing Source: GO_Central
Names & Taxonomyi
Protein namesi | Recommended name: Integrator complex subunit 4 homolog |
Gene namesi | Name:ints4 ORF Names:DDB_G0286633 |
Organismi | Dictyostelium discoideum (Slime mold) |
Taxonomic identifieri | 44689 [NCBI] |
Taxonomic lineagei | Eukaryota › Amoebozoa › Evosea › Eumycetozoa › Dictyostelia › Dictyosteliales › Dictyosteliaceae › Dictyostelium |
Proteomesi |
|
Organism-specific databases
dictyBasei | DDB_G0286633, ints4 |
Subcellular locationi
- Nucleus By similarity
GO - Cellular componenti
- integrator complex Source: GO_Central
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000344376 | 1 – 1233 | Integrator complex subunit 4 homologAdd BLAST | 1233 |
Proteomic databases
PaxDbi | Q54LH5 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 236 – 273 | HEAT 1Add BLAST | 38 | |
Repeati | 275 – 310 | HEAT 2Add BLAST | 36 | |
Repeati | 487 – 524 | HEAT 3Add BLAST | 38 | |
Repeati | 525 – 561 | HEAT 4Add BLAST | 37 | |
Repeati | 563 – 597 | HEAT 5Add BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 12 – 25 | Poly-GlnAdd BLAST | 14 | |
Compositional biasi | 28 – 94 | Poly-GlnAdd BLAST | 67 | |
Compositional biasi | 428 – 444 | Poly-GlnAdd BLAST | 17 | |
Compositional biasi | 723 – 733 | Poly-AsnAdd BLAST | 11 | |
Compositional biasi | 766 – 792 | Poly-AsnAdd BLAST | 27 | |
Compositional biasi | 979 – 987 | Poly-Asn | 9 | |
Compositional biasi | 1054 – 1064 | Poly-ThrAdd BLAST | 11 | |
Compositional biasi | 1200 – 1206 | Poly-Asn | 7 |
Sequence similaritiesi
Belongs to the Integrator subunit 4 family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | KOG2259, Eukaryota |
HOGENOMi | CLU_267504_0_0_1 |
InParanoidi | Q54LH5 |
OMAi | NCACKLL |
Family and domain databases
Gene3Di | 1.25.10.10, 2 hits |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold |
SUPFAMi | SSF48371, SSF48371, 1 hit |
i Sequence
Sequence statusi: Complete.
Q54LH5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNKKSHQQQV LQQQQQQQQQ QFQQQHFQQQ QQQQQFQQQQ QQQQQLQQQQ
60 70 80 90 100
LQQQQQQQIQ QQQQIQQQQQ QQQQQQQQIQ QQQQPQQIQQ PQQQLPNFSV
110 120 130 140 150
PIINQSIISN IKLYSTFETL LLSLSSTDTR EQTKAIIYLS SLTINNKSNG
160 170 180 190 200
IDLVYCIQKQ LVVEAHNHIK VLLINLLGDI SLDPFIDSFH ILNKLLYLIR
210 220 230 240 250
NEKSKKVLSS CLININKISK SLTFSKGNDV NSSSSSLINQ IIEYIEPLLH
260 270 280 290 300
STSPLVRRET IVLLGSIVKN LDKESEEIQI LLLNYLKDTD FRVREASLKS
310 320 330 340 350
LSVIFQRGAS LSVNKLYQSI ILLLLDSFEQ VRLECIKLIW IFGNIYPNHI
360 370 380 390 400
VVSGGTKIRL VDDVFKKICN AVNDSSVIVR NCACKLLGCT YDVSLNYLIQ
410 420 430 440 450
TLSKEVMVWG KGKQYQIGHS SITKQRLQQK QQQQQQQQQQ QQQQPPQQQP
460 470 480 490 500
SQQPNQQPNQ QQTNVSGTHI ATPEGDFDVV GSDSLNILES GVIGAFIQGL
510 520 530 540 550
EDEFYEVRSS AIDSMCELSV RNDEFAQKNI DFLVDIFNDE IESVRINSIN
560 570 580 590 600
SLRKIGNNVV IKEEQLHIIL ANLESSSKEE RQSLHRLLTS IHLSNYSCLH
610 620 630 640 650
ATTQALLMNL SRYPYDIHSI FETLKIIGQT NPFTEFIVDD LLRIDPKFAS
660 670 680 690 700
VEPNMDDIFY VAVMVLVLNS CIKNRNILSL LPSFSFQHHL YFKDKYPKYF
710 720 730 740 750
PQNLQKDSNI ILAPTLKYSS VVNNNNNKNN NNNTTTTSII NDNGEINQFL
760 770 780 790 800
NLTLSLLYGD NNNIINNNNT NNNNNNNNNN NNNNNNNNNN NNDENDENLN
810 820 830 840 850
YGFQRLFLNQ KKEIQLNKLF QECKRNFKRI SSICLSLKPT SDFYNKYLKI
860 870 880 890 900
LTTIVSSSRR FKTITTSNQL NHLLYKLNHK FIGVDNNCKL ILMEIGIYSF
910 920 930 940 950
IIEILSTITL STSSPPTTTT TTSSTSLFTS INSTPIELSN DQINQLTKKL
960 970 980 990 1000
NEYFKFSNDF KLEISTSIKS LLDLFNIKNN NINNNNNIIN KKDKKLKENE
1010 1020 1030 1040 1050
ENEENEENEN NENENEKENG KNKEKEKNEN DNENENENER PSKIQKTTSE
1060 1070 1080 1090 1100
LIKTTTTTST STSTLIHYNL IEWTDNYIPP ILKISNLIKK KSVDVILPIP
1110 1120 1130 1140 1150
NDKPIEFLDI FPLKLMINAK IENIRNLDSL FIQSTWQSIH TGQLNSQIHI
1160 1170 1180 1190 1200
IPKSAFTPTK PLSYNISCSI YLSLQNIRHN RLSSKESIPL RISIVEQFLN
1210 1220 1230
NNNNNNVTII PLSKFVIFNI LPVDNVNLLP NLI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000089 Genomic DNA Translation: EAL64072.1 |
RefSeqi | XP_637586.1, XM_632494.1 |
Genome annotation databases
EnsemblProtistsi | EAL64072; EAL64072; DDB_G0286633 |
GeneIDi | 8625726 |
KEGGi | ddi:DDB_G0286633 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000089 Genomic DNA Translation: EAL64072.1 |
RefSeqi | XP_637586.1, XM_632494.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 44689.DDB0234080 |
Proteomic databases
PaxDbi | Q54LH5 |
Genome annotation databases
EnsemblProtistsi | EAL64072; EAL64072; DDB_G0286633 |
GeneIDi | 8625726 |
KEGGi | ddi:DDB_G0286633 |
Organism-specific databases
dictyBasei | DDB_G0286633, ints4 |
Phylogenomic databases
eggNOGi | KOG2259, Eukaryota |
HOGENOMi | CLU_267504_0_0_1 |
InParanoidi | Q54LH5 |
OMAi | NCACKLL |
Miscellaneous databases
PROi | PR:Q54LH5 |
Family and domain databases
Gene3Di | 1.25.10.10, 2 hits |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold |
SUPFAMi | SSF48371, SSF48371, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | INT4_DICDI | |
Accessioni | Q54LH5Primary (citable) accession number: Q54LH5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 22, 2008 |
Last sequence update: | May 24, 2005 | |
Last modified: | December 2, 2020 | |
This is version 83 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Dictyostelium discoideum
Dictyostelium discoideum: entries, gene names and cross-references to dictyBase - SIMILARITY comments
Index of protein domains and families