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UniProtKB - Q54KA7 (SECG_DICDI)
Protein
Ankyrin repeat, PH and SEC7 domain containing protein secG
Gene
secG
Organism
Dictyostelium discoideum (Slime mold)
Status
Functioni
GO - Molecular functioni
- guanyl-nucleotide exchange factor activity Source: InterPro
GO - Biological processi
- actin cytoskeleton organization Source: dictyBase
- cell-substrate adhesion Source: dictyBase
- chemotaxis Source: dictyBase
- chemotaxis to cAMP Source: dictyBase
- culmination involved in sorocarp development Source: dictyBase
- regulation of ARF protein signal transduction Source: InterPro
Names & Taxonomyi
Protein namesi | Recommended name: Ankyrin repeat, PH and SEC7 domain containing protein secG |
Gene namesi | Name:secG ORF Names:DDB_G0287459 |
Organismi | Dictyostelium discoideum (Slime mold) |
Taxonomic identifieri | 44689 [NCBI] |
Taxonomic lineagei | Eukaryota › Amoebozoa › Evosea › Eumycetozoa › Dictyostelia › Dictyosteliales › Dictyosteliaceae › Dictyostelium |
Proteomesi |
|
Organism-specific databases
dictyBasei | DDB_G0287459, secG |
Subcellular locationi
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000334489 | 1 – 986 | Ankyrin repeat, PH and SEC7 domain containing protein secGAdd BLAST | 986 |
Proteomic databases
PaxDbi | Q54KA7 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 34 – 63 | ANK 1Add BLAST | 30 | |
Repeati | 68 – 97 | ANK 2Add BLAST | 30 | |
Repeati | 101 – 131 | ANK 3Add BLAST | 31 | |
Repeati | 135 – 164 | ANK 4Add BLAST | 30 | |
Repeati | 168 – 197 | ANK 5Add BLAST | 30 | |
Repeati | 201 – 230 | ANK 6Add BLAST | 30 | |
Repeati | 234 – 263 | ANK 7Add BLAST | 30 | |
Repeati | 267 – 296 | ANK 8Add BLAST | 30 | |
Repeati | 300 – 329 | ANK 9Add BLAST | 30 | |
Repeati | 334 – 363 | ANK 10Add BLAST | 30 | |
Repeati | 367 – 396 | ANK 11Add BLAST | 30 | |
Repeati | 400 – 429 | ANK 12Add BLAST | 30 | |
Repeati | 433 – 462 | ANK 13Add BLAST | 30 | |
Repeati | 466 – 495 | ANK 14Add BLAST | 30 | |
Repeati | 499 – 528 | ANK 15Add BLAST | 30 | |
Domaini | 580 – 770 | SEC7PROSITE-ProRule annotationAdd BLAST | 191 | |
Domaini | 784 – 895 | PHPROSITE-ProRule annotationAdd BLAST | 112 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 43 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 911 – 986 | DisorderedSequence analysisAdd BLAST | 76 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 920 – 986 | Polar residuesSequence analysisAdd BLAST | 67 |
Keywords - Domaini
ANK repeat, RepeatPhylogenomic databases
eggNOGi | KOG0930, Eukaryota KOG4177, Eukaryota |
HOGENOMi | CLU_302561_0_0_1 |
InParanoidi | Q54KA7 |
OMAi | DHEPCGI |
PhylomeDBi | Q54KA7 |
Family and domain databases
CDDi | cd00171, Sec7, 1 hit |
Gene3Di | 1.10.1000.11, 1 hit 1.25.40.20, 4 hits 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR023394, Sec7_C_sf IPR000904, Sec7_dom IPR035999, Sec7_dom_sf |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 5 hits PF00169, PH, 1 hit PF01369, Sec7, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 15 hits SM00233, PH, 1 hit SM00222, Sec7, 1 hit |
SUPFAMi | SSF48403, SSF48403, 2 hits SSF48425, SSF48425, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 13 hits PS50003, PH_DOMAIN, 1 hit PS50190, SEC7, 1 hit |
i Sequence
Sequence statusi: Complete.
Q54KA7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSTSNSTKN TGSTTTTTTT AAPATTAKHS NSAPTRPSVH YYSSTGDIEK
60 70 80 90 100
LSNLLNNSAT SPDTPDSEKR TPLHHAAFCG SAACVNFLLD KKANANIKDS
110 120 130 140 150
AGNTPLQWAS SRGHLECIKL LVEKGGVDVN TKDDKNGTPL HKASLFASAE
160 170 180 190 200
CVLYLLNGKA DPRAVTTNGE TPLHHASAGG NPQCVELLIK ADSKVNAVDN
210 220 230 240 250
DCITPLHQAS FSGHSSCVSL LLKKGAKVDP RDIHGISPLH NAASAGYVDC
260 270 280 290 300
VEQLVRNGEN INCVDIEGVT PLHHTCFNGN LQLTKRLIEL GAKINMVDEM
310 320 330 340 350
GETPLHKAAF NGHKEVCEYL LYLDPTMIDC RDSRQSTSLH LAAFNGLLDM
360 370 380 390 400
VDLLIRYKAQ INIKDEEGAT PLHKASFNGH SSCAKLLVDK GAPICIVDSQ
410 420 430 440 450
GATPLHKAAF NGRSKCLATL IRSGAELEVK DSQGGTPLHN AAYNGHSDCC
460 470 480 490 500
RILLKKGANV NAVDTHSSTP LHLASAAGAR DTVDVLIQFK ARIDAKNFAG
510 520 530 540 550
KTPLVYAIKK NHSDVARVLI RAGADLDQVS LRSSVDFTKT FGTENHDEIY
560 570 580 590 600
QIVNKRESSN HEVDELQLAL EQQAKEDMEQ LAAEKQKLLL IKAAIAQFNS
610 620 630 640 650
HPKKGIEFIV ANGVISEKNP KEVAHFLLTH SELSKQSIGE YIGEGDDFNL
660 670 680 690 700
QVLHAFVDEL NFFGLDFDVA LRKYLLTFRL PGEAQKIDRM MEKFASQFYQ
710 720 730 740 750
HNPENKVFVN QDAVYVLAFS VIMLNTDAHN PNIKKKMTKA EFLRNNSGIN
760 770 780 790 800
SGDDLPPDFM ENLYDKIVTN EIKMERDGNQ ANQHVEKKGW LTKQGGRIKT
810 820 830 840 850
WKKRWFILTA NCLLYYKTPQ DHEPCGIIPL ENVVVTIDPQ KKFCFMLHSS
860 870 880 890 900
QEQMKACKLN SDGTLVQANH AAYFIAAANM AEMDSWVQSI KSNIHSNPNF
910 920 930 940 950
EQLLKRKAET IRGRGKVSTK PIQNRKQTIS GPPPSTTTTT TSTASNNVTS
960 970 980
VGSPPNSGSV LNSSGSKPVT FSSTSSPVQQ QTSALS
Sequence cautioni
The sequence AAB36958 differs from that shown. Reason: Frameshift.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000101 Genomic DNA Translation: EAL63695.1 U78755 mRNA Translation: AAB36958.1 Frameshift. |
RefSeqi | XP_637214.1, XM_632122.1 |
Genome annotation databases
EnsemblProtistsi | EAL63695; EAL63695; DDB_G0287459 |
GeneIDi | 8626150 |
KEGGi | ddi:DDB_G0287459 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000101 Genomic DNA Translation: EAL63695.1 U78755 mRNA Translation: AAB36958.1 Frameshift. |
RefSeqi | XP_637214.1, XM_632122.1 |
3D structure databases
SMRi | Q54KA7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 44689.DDB0191439 |
Proteomic databases
PaxDbi | Q54KA7 |
Genome annotation databases
EnsemblProtistsi | EAL63695; EAL63695; DDB_G0287459 |
GeneIDi | 8626150 |
KEGGi | ddi:DDB_G0287459 |
Organism-specific databases
dictyBasei | DDB_G0287459, secG |
Phylogenomic databases
eggNOGi | KOG0930, Eukaryota KOG4177, Eukaryota |
HOGENOMi | CLU_302561_0_0_1 |
InParanoidi | Q54KA7 |
OMAi | DHEPCGI |
PhylomeDBi | Q54KA7 |
Miscellaneous databases
PROi | PR:Q54KA7 |
Family and domain databases
CDDi | cd00171, Sec7, 1 hit |
Gene3Di | 1.10.1000.11, 1 hit 1.25.40.20, 4 hits 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR023394, Sec7_C_sf IPR000904, Sec7_dom IPR035999, Sec7_dom_sf |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 5 hits PF00169, PH, 1 hit PF01369, Sec7, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 15 hits SM00233, PH, 1 hit SM00222, Sec7, 1 hit |
SUPFAMi | SSF48403, SSF48403, 2 hits SSF48425, SSF48425, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 13 hits PS50003, PH_DOMAIN, 1 hit PS50190, SEC7, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SECG_DICDI | |
Accessioni | Q54KA7Primary (citable) accession number: Q54KA7 Secondary accession number(s): P90525 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 20, 2008 |
Last sequence update: | May 24, 2005 | |
Last modified: | February 23, 2022 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Dictyostelium discoideum
Dictyostelium discoideum: entries, gene names and cross-references to dictyBase