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Protein

Ras-related protein Rab-7B

Gene

rab7B

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Protein transport. Probably involved in vesicular traffic (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 21GTPBy similarity8
Nucleotide bindingi33 – 38GTPBy similarity6
Nucleotide bindingi57 – 61GTPBy similarity5
Nucleotide bindingi119 – 122GTPBy similarity4
Nucleotide bindingi152 – 153GTPBy similarity2

GO - Molecular functioni

  • GTPase activity Source: GO_Central
  • GTP binding Source: UniProtKB-KW

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DDI-6798695 Neutrophil degranulation
R-DDI-8854214 TBC/RABGAPs
R-DDI-8873719 RAB geranylgeranylation
R-DDI-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein Rab-7B
Gene namesi
Name:rab7B
ORF Names:DDB_G0287553
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0287553 rab7B

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003125591 – 197Ras-related protein Rab-7BAdd BLAST197

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi196S-geranylgeranyl cysteineBy similarity1
Lipidationi197S-geranylgeranyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Prenylation

Proteomic databases

PaxDbiQ54K69

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0229399

Structurei

3D structure databases

ProteinModelPortaliQ54K69
SMRiQ54K69
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi31 – 39Effector regionBy similarity9

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0394 Eukaryota
ENOG410XNZV LUCA
InParanoidiQ54K69
KOiK07897
OMAiHIESWIK
PhylomeDBiQ54K69

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51419 RAB, 1 hit

Sequencei

Sequence statusi: Complete.

Q54K69-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKGRKIIKV VIIGEKSVGK TSILRRYVDK RFVTLKPTIG VDFVMVSENM
60 70 80 90 100
VTLQLWDTSG QERFRSLEIS YYRGADYCIL VFDVTNEKTL YDLKLWRDDF
110 120 130 140 150
IEKTEIRDPI LFPFIILGNK IDDPNRVVTE KAAIQWCKDN IGGNLTYFDT
160 170 180 190
SAKDNINIEQ VFKHISNQCE NQPQSNEIPP EQLISLTEKK SNQSSCC
Length:197
Mass (Da):22,752
Last modified:May 24, 2005 - v1
Checksum:i745BF98B55537E54
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000102 Genomic DNA Translation: EAL63676.1
RefSeqiXP_637186.1, XM_632094.1

Genome annotation databases

EnsemblProtistsiEAL63676; EAL63676; DDB_G0287553
GeneIDi8626187
KEGGiddi:DDB_G0287553

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000102 Genomic DNA Translation: EAL63676.1
RefSeqiXP_637186.1, XM_632094.1

3D structure databases

ProteinModelPortaliQ54K69
SMRiQ54K69
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0229399

Proteomic databases

PaxDbiQ54K69

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL63676; EAL63676; DDB_G0287553
GeneIDi8626187
KEGGiddi:DDB_G0287553

Organism-specific databases

dictyBaseiDDB_G0287553 rab7B

Phylogenomic databases

eggNOGiKOG0394 Eukaryota
ENOG410XNZV LUCA
InParanoidiQ54K69
KOiK07897
OMAiHIESWIK
PhylomeDBiQ54K69

Enzyme and pathway databases

ReactomeiR-DDI-6798695 Neutrophil degranulation
R-DDI-8854214 TBC/RABGAPs
R-DDI-8873719 RAB geranylgeranylation
R-DDI-8876198 RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

PROiPR:Q54K69

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51419 RAB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRAB7B_DICDI
AccessioniPrimary (citable) accession number: Q54K69
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: May 24, 2005
Last modified: November 7, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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