UniProtKB - Q54JR2 (ABCC3_DICDI)
Protein
ABC transporter C family member 3
Gene
abcC3
Organism
Dictyostelium discoideum (Slime mold)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 474 – 481 | ATPPROSITE-ProRule annotation | 8 | |
Nucleotide bindingi | 1096 – 1103 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATPase-coupled transmembrane transporter activity Source: GO_Central
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- culmination involved in sorocarp development Source: dictyBase
- transmembrane transport Source: GO_Central
Keywordsi
Biological process | Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
Reactomei | R-DDI-382556 ABC-family proteins mediated transport R-DDI-8856825 Cargo recognition for clathrin-mediated endocytosis R-DDI-8856828 Clathrin-mediated endocytosis |
Names & Taxonomyi
Protein namesi | Recommended name: ABC transporter C family member 3Alternative name(s): ABC transporter ABCC.3 |
Gene namesi | Name:abcC3 ORF Names:DDB_G0287691 |
Organismi | Dictyostelium discoideum (Slime mold) |
Taxonomic identifieri | 44689 [NCBI] |
Taxonomic lineagei | Eukaryota › Amoebozoa › Evosea › Eumycetozoa › Dictyostelids › Dictyosteliales › Dictyosteliaceae › Dictyostelium |
Proteomesi |
|
Organism-specific databases
dictyBasei | DDB_G0287691 abcC3 |
Subcellular locationi
- Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 115 – 135 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 161 – 181 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 236 – 256 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 261 – 281 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 346 – 366 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 379 – 399 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 724 – 744 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 787 – 807 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 854 – 874 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 875 – 895 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 967 – 987 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000363849 | 1 – 1412 | ABC transporter C family member 3Add BLAST | 1412 |
Proteomic databases
PaxDbi | Q54JR2 |
PRIDEi | Q54JR2 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 119 – 405 | ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST | 287 | |
Domaini | 439 – 662 | ABC transporter 1PROSITE-ProRule annotationAdd BLAST | 224 | |
Domaini | 735 – 1025 | ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST | 291 | |
Domaini | 1062 – 1296 | ABC transporter 2PROSITE-ProRule annotationAdd BLAST | 235 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1368 – 1406 | Poly-AsnAdd BLAST | 39 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. [View classification]Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0054 Eukaryota COG1132 LUCA |
InParanoidi | Q54JR2 |
OMAi | PWIMNAS |
PhylomeDBi | Q54JR2 |
Family and domain databases
Gene3Di | 1.20.1560.10, 2 hits |
InterProi | View protein in InterPro IPR003593 AAA+_ATPase IPR011527 ABC1_TM_dom IPR036640 ABC1_TM_sf IPR003439 ABC_transporter-like IPR017871 ABC_transporter_CS IPR027417 P-loop_NTPase |
Pfami | View protein in Pfam PF00664 ABC_membrane, 2 hits PF00005 ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382 AAA, 2 hits |
SUPFAMi | SSF52540 SSF52540, 2 hits SSF90123 SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929 ABC_TM1F, 2 hits PS00211 ABC_TRANSPORTER_1, 1 hit PS50893 ABC_TRANSPORTER_2, 2 hits |
i Sequence
Sequence statusi: Complete.
Q54JR2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MELEEVGVEA NQPNNDQGSK KQNKNKDKKV KKEKKIGYGG KKSAEENSNF
60 70 80 90 100
ISWLTFSWAD RFVVHCFRHV LQLSHIWDLA SYDKSAYLAE KIAISWDVEI
110 120 130 140 150
KKPKPSYIRA AFRAFGLYFV LSWFFYAIYA ASQFVGPEIL KRMVTFVLKS
160 170 180 190 200
RSGISTEDPN MGYYYALIMF GSAMIGSVCL YQSNMISART GDRLRSVIVL
210 220 230 240 250
DVYRKAIKLS NSARANTSPG EIVNLMSNDA QRMVEVFQLV NNGVFALPQI
260 270 280 290 300
IVCLALLYRA IGWPTFVGLG LMLAAVPFNG IAAKKLTEIR RHLVGFTDKR
310 320 330 340 350
VKTTNEILQA IKIIKLYAWE DSFAKKVIER REAEIKLLFS FSRYRAMLIV
360 370 380 390 400
IVAALPTAVS VLVFSSYYGY YKKLDAGEIF AALSYLNILR LPLGFLPIIV
410 420 430 440 450
ALGIQMKIAA QRVTDFLLLP EMKEISKIED PSIENGIYIR DATLTWNQEK
460 470 480 490 500
KEESFTLKNI NFEAKGKTLT MIVGSVGSGK SSLIQAMLGE MDVLDGSVAM
510 520 530 540 550
KGNVAYVPQQ AWIINATLKD NILFGSPYDE AKYRKVLEVC ALERDIELFP
560 570 580 590 600
QGDLVEIGER GVNLSGGQKQ RVSIARAVYS DSDVYILDDP LSAVDAHVGK
610 620 630 640 650
HLFHRCFKGI LKSKTVILAA NQLNYLPFAH NTVVLKAGEI SERGSYQQLI
660 670 680 690 700
NAQKEFSGLL QAYGVDESAV NEDVEDDKEI EESDNIVVEE KTKPTEKPKL
710 720 730 740 750
QNKDGVLTSQ EEREEGAVAM WVYWKYITVG GGFLFLMAFI FFLMDTGTRT
760 770 780 790 800
FVDWWLSHWQ NESTKNALAV AQGLEPSGLT DTQYLGIYIG VGMTSILISA
810 820 830 840 850
GRNFLFFEYT VRASRALHHQ LFNALLRAPM SFFDTTPLGR IINRFTRDLD
860 870 880 890 900
GVDNLMATSI SQFLVFFTTV VATLIIISII TPFLLVPLAP ICIIFYFLQF
910 920 930 940 950
FYRYTSRELQ RLEAISRSPI FSHFSETLGG VVSIRAYRKK EENILTNQFR
960 970 980 990 1000
LDNNNKCYLT LQAMNQWLGL RLDLLANLVT FFACLFITID RDTISAANVG
1010 1020 1030 1040 1050
LSLSYALSLT GNLNRATLQA ADTETKMNSV ERITHYIKGP VEALQIVEDH
1060 1070 1080 1090 1100
RPAPDWPPHG AITFDNLVMR YREGLDPVLK GISCEIKAKE KIGIVGRTGA
1110 1120 1130 1140 1150
GKSSIVLALF RLIEASEGAI LIDGENIAKF GLKDLRRNLA IIPQDPVLFS
1160 1170 1180 1190 1200
GTLRENIDPF NEKTDDQLWS VLKDIQLHDV AKSLEGGLDS KVTENGDNWS
1210 1220 1230 1240 1250
VGQRQLLCLA RALLRDPKIL VLDEATASVD GHSDSLIQAT IREKFSNCTI
1260 1270 1280 1290 1300
LTIAHRLNTI MDSDRIIVLD AGKISEFDEP WTLLQNPAGL LNWLVEETGP
1310 1320 1330 1340 1350
QNAAYLRRLA QAKKDGVNID QITPPISPTP EQKPFKNADI DNINSPPQQS
1360 1370 1380 1390 1400
LKAEDNPNPK ALDNSGDNNN NNNNNNNNNN NNNNNNNNNN NNNNNNDNDN
1410
DNDNDNSEAG DN
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 191 – 212 | Missing in AAL85706 (PubMed:12456012).CuratedAdd BLAST | 22 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF474335 Genomic DNA Translation: AAL85706.1 AAFI02000104 Genomic DNA Translation: EAL63492.1 |
RefSeqi | XP_637090.1, XM_631998.1 |
Genome annotation databases
EnsemblProtistsi | EAL63492; EAL63492; DDB_G0287691 |
GeneIDi | 8626345 |
KEGGi | ddi:DDB_G0287691 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF474335 Genomic DNA Translation: AAL85706.1 AAFI02000104 Genomic DNA Translation: EAL63492.1 |
RefSeqi | XP_637090.1, XM_631998.1 |
3D structure databases
SMRi | Q54JR2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 44689.DDB0216251 |
Proteomic databases
PaxDbi | Q54JR2 |
PRIDEi | Q54JR2 |
Genome annotation databases
EnsemblProtistsi | EAL63492; EAL63492; DDB_G0287691 |
GeneIDi | 8626345 |
KEGGi | ddi:DDB_G0287691 |
Organism-specific databases
dictyBasei | DDB_G0287691 abcC3 |
Phylogenomic databases
eggNOGi | KOG0054 Eukaryota COG1132 LUCA |
InParanoidi | Q54JR2 |
OMAi | PWIMNAS |
PhylomeDBi | Q54JR2 |
Enzyme and pathway databases
Reactomei | R-DDI-382556 ABC-family proteins mediated transport R-DDI-8856825 Cargo recognition for clathrin-mediated endocytosis R-DDI-8856828 Clathrin-mediated endocytosis |
Miscellaneous databases
PROi | PR:Q54JR2 |
Family and domain databases
Gene3Di | 1.20.1560.10, 2 hits |
InterProi | View protein in InterPro IPR003593 AAA+_ATPase IPR011527 ABC1_TM_dom IPR036640 ABC1_TM_sf IPR003439 ABC_transporter-like IPR017871 ABC_transporter_CS IPR027417 P-loop_NTPase |
Pfami | View protein in Pfam PF00664 ABC_membrane, 2 hits PF00005 ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382 AAA, 2 hits |
SUPFAMi | SSF52540 SSF52540, 2 hits SSF90123 SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929 ABC_TM1F, 2 hits PS00211 ABC_TRANSPORTER_1, 1 hit PS50893 ABC_TRANSPORTER_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ABCC3_DICDI | |
Accessioni | Q54JR2Primary (citable) accession number: Q54JR2 Secondary accession number(s): Q8T6H6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 10, 2009 |
Last sequence update: | May 24, 2005 | |
Last modified: | October 16, 2019 | |
This is version 97 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Dictyostelium discoideum
Dictyostelium discoideum: entries, gene names and cross-references to dictyBase