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Protein

Nitrilase homolog 2

Gene

nit2

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei92Proton acceptorPROSITE-ProRule annotation1
Active sitei163Proton donorPROSITE-ProRule annotation1
Active sitei204NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

ReactomeiR-DDI-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Nitrilase homolog 2 (EC:3.5.-.-)
Gene namesi
Name:nit2
ORF Names:DDB_G0287939
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0287939 nit2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003329731 – 328Nitrilase homolog 2Add BLAST328

Proteomic databases

PaxDbiQ54JM9

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0302493

Structurei

3D structure databases

ProteinModelPortaliQ54JM9
SMRiQ54JM9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 299CN hydrolasePROSITE-ProRule annotationAdd BLAST247

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi21 – 25Poly-Asn5

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0806 Eukaryota
COG0388 LUCA
InParanoidiQ54JM9
KOiK13566
OMAiTGKDHWQ
PhylomeDBiQ54JM9

Family and domain databases

Gene3Di3.60.110.10, 1 hit
InterProiView protein in InterPro
IPR003010 C-N_Hydrolase
IPR036526 C-N_Hydrolase_sf
IPR001110 UPF0012_CS
PfamiView protein in Pfam
PF00795 CN_hydrolase, 1 hit
SUPFAMiSSF56317 SSF56317, 1 hit
PROSITEiView protein in PROSITE
PS50263 CN_HYDROLASE, 1 hit
PS01227 UPF0012, 1 hit

Sequencei

Sequence statusi: Complete.

Q54JM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYRGLINSFK NTSKFSTSLF NNNNNCSTTT KSFTHISQQL RKVHLMADKE
60 70 80 90 100
KVFKFAGIQL LCGDNKEENV QNAIKHIDEA AKNGAKLISL PECFNSPYST
110 120 130 140 150
STFEKYSETE DGETVKKLSE AAKRNQIFLV GGSIPEIDKA TGKIYNTCFI
160 170 180 190 200
FNDKGEVVKK HRKIHLFDID VPNKIRFKES ETLTPGDSFS VVDIGYCKIG
210 220 230 240 250
VAICYDIRFP ELAMLYSKMG AKFLIYPGAF NMVTGPAHWE LLQRGRAVDN
260 270 280 290 300
QVFVAAISPA RNPSSTYQAW GHSTIVNSWG TILATTDEHQ SIIYSDIDLN
310 320
TLNETRSSIP IYSQKRDDLY KLDSIKKQ
Length:328
Mass (Da):36,945
Last modified:May 24, 2005 - v1
Checksum:i80EA9A1BA2537BEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000105 Genomic DNA Translation: EAL63476.1
RefSeqiXP_636983.1, XM_631891.1

Genome annotation databases

EnsemblProtistsiEAL63476; EAL63476; DDB_G0287939
GeneIDi8626377
KEGGiddi:DDB_G0287939

Similar proteinsi

Entry informationi

Entry nameiNIT2_DICDI
AccessioniPrimary (citable) accession number: Q54JM9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 24, 2005
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

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