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Entry version 61 (05 Dec 2018)
Sequence version 1 (24 May 2005)
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Protein

WASH complex subunit 5

Gene

washc5

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • actin filament polymerization Source: dictyBase
  • endosome organization Source: dictyBase
  • exocytosis Source: dictyBase
  • lysosome organization Source: dictyBase
  • phagosome reneutralization Source: dictyBase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WASH complex subunit 5By similarity
Alternative name(s):
WASH complex subunit strumpellin homologCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:washc5By similarity
ORF Names:DDB_G0288569
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0288569 washc5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: dictyBase
  • WASH complex Source: dictyBase

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003293112 – 1164WASH complex subunit 5Add BLAST1163

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q54IR8

PRoteomics IDEntifications database

More...
PRIDEi
Q54IR8

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Probable component of the WASH complex.By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0234050

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q54IR8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the strumpellin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3666 Eukaryota
ENOG410XNSS LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q54IR8

KEGG Orthology (KO)

More...
KOi
K18464

Identification of Orthologs from Complete Genome Data

More...
OMAi
QSIHHYA

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q54IR8

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019393 WASH_strumpellin

The PANTHER Classification System

More...
PANTHERi
PTHR15691 PTHR15691, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10266 Strumpellin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q54IR8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVKEFLGEGS QAGQNLLRLV SRGNAIIAEL LRLSAHIPSV FKLEDRNEAR
60 70 80 90 100
KYQDILLDFK YLSNPDFYES KIEENADLVD LETEFRDNHI DILIRFYHLF
110 120 130 140 150
ESIYKYIMDL EHYIVDVEKG FYIHLTIEAI LINGDGKQLL SEAVYLYGVM
160 170 180 190 200
LILMDNLIEG PVRERMLISY LRNKGPVDLP LIDEVCKLCK STGYIPGSPK
210 220 230 240 250
KPPNYPEEYF RRVELPENVI SMIVGRLRSD DLYNGTESFP QPEHRSVALS
260 270 280 290 300
TQACMIYVIL YFIPDILNNK NSIMREIVDK FFPDNWVISF FLGFTIDLSV
310 320 330 340 350
AWEPYKAAKT AMGNTIIQSN IQYQTQRFWK EVSELNKLVD DLLVDGLLVE
360 370 380 390 400
EYIVDNVHKI ITTLRRCNVT IRWVMLHSNA SQKKFKDLVL MGGSQEDVLY
410 420 430 440 450
LLLNTAQLEF VFKNIFQQLL ATKEEKWEEN KKLASDSMVE LSEYFSGEKA
460 470 480 490 500
LTRVKKNENL QKWFGEISQK ISQLDSTDST STGRKIQQLS LALEEVEQFQ
510 520 530 540 550
QIDSSIQVKQ FLIETRQFLT KMIKIVNIKE EVLVNLSVCA DMSYAWEIVN
560 570 580 590 600
NYVDQMQKGI KSDPKCVLKL RATFLKLVSI LDLPLVRIAQ CSSPDLISVS
610 620 630 640 650
EYYSGELVGY VRKVLEIVPK QMFLILKQII NMQTNNIQEM PTKVEKERLR
660 670 680 690 700
DFAQLDQRYD LARATHSVSV FTEGILAMET TLVGIIEVDP KQLLEDGIRK
710 720 730 740 750
ELVLQIALAM DKTLIFSGKP YQAPSNKQQQ QEIELLQRLK ELSNILDGFR
760 770 780 790 800
RSFQYIQDYV NIQGLKIWQE EFSRIVNFYV EQECNSFLKK KVYDWQSQYQ
810 820 830 840 850
SVAIPIPKFP SQSDQNSQQS VNMIGRLARE LLNQTNCKTT LYLNQIGWFD
860 870 880 890 900
PSSGKELVGI NTWSILHQSV GIFGLTGLDK LFSFMMVKDL QVFVSQTRSL
910 920 930 940 950
VEKSLKGFLN EFEDYLRPTT NIPDTMIRYQ QALDKTKLLY PIFIDVLTKI
960 970 980 990 1000
GQIQLIRRQI SNQLNFHCKI DSNMLFSSLD IMNKSLLNDI ESHFQRPDSN
1010 1020 1030 1040 1050
PYPSDDNTLL FDLAQYLDTA GINDPFTKIY ITTSPLEQFP CLLFLFVLSQ
1060 1070 1080 1090 1100
VSKFQFNSKL NVMSSKKQKN SYDWTPFIIG CITILQQFHS LHTQKFLAFV
1110 1120 1130 1140 1150
GQYIKSHINI ALANPKENNK DDADYPEDVI GLLRFLEDFC KYSHTSRKIV
1160
EGYVPPYIFD YYNN
Length:1,164
Mass (Da):134,897
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i17865EB8513B9A6A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000117 Genomic DNA Translation: EAL63144.1

NCBI Reference Sequences

More...
RefSeqi
XP_636646.1, XM_631554.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL63144; EAL63144; DDB_G0288569

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8626692

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0288569

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000117 Genomic DNA Translation: EAL63144.1
RefSeqiXP_636646.1, XM_631554.1

3D structure databases

SMRiQ54IR8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0234050

Proteomic databases

PaxDbiQ54IR8
PRIDEiQ54IR8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL63144; EAL63144; DDB_G0288569
GeneIDi8626692
KEGGiddi:DDB_G0288569

Organism-specific databases

dictyBaseiDDB_G0288569 washc5

Phylogenomic databases

eggNOGiKOG3666 Eukaryota
ENOG410XNSS LUCA
InParanoidiQ54IR8
KOiK18464
OMAiQSIHHYA
PhylomeDBiQ54IR8

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q54IR8

Family and domain databases

InterProiView protein in InterPro
IPR019393 WASH_strumpellin
PANTHERiPTHR15691 PTHR15691, 1 hit
PfamiView protein in Pfam
PF10266 Strumpellin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWASC5_DICDI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q54IR8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: December 5, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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