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UniProtKB - Q54F25 (CLN3_DICDI)
Protein
Battenin
Gene
cln3
Organism
Dictyostelium discoideum (Slime mold)
Status
Functioni
GO - Biological processi
- aggregation involved in sorocarp development Source: dictyBase
- arginine transport Source: GO_Central
- cell-cell adhesion Source: dictyBase
- cell-substrate adhesion Source: dictyBase
- cellular water homeostasis Source: dictyBase
- hyperosmotic response Source: dictyBase
- hypotonic response Source: dictyBase
- mitotic cytokinesis Source: dictyBase
- negative regulation of cell population proliferation Source: dictyBase
- negative regulation of protein secretion Source: dictyBase
- pinocytosis Source: dictyBase
- positive regulation of protein secretion Source: dictyBase
- regulation of intracellular pH Source: GO_Central
- regulation of protein secretion Source: dictyBase
- regulation of sorocarp development Source: dictyBase
Names & Taxonomyi
Protein namesi | Recommended name: BatteninAlternative name(s): Protein CLN3 homolog |
Gene namesi | Name:cln3 ORF Names:DDB_G0291157 |
Organismi | Dictyostelium discoideum (Slime mold) |
Taxonomic identifieri | 44689 [NCBI] |
Taxonomic lineagei | Eukaryota › Amoebozoa › Evosea › Eumycetozoa › Dictyostelia › Dictyosteliales › Dictyosteliaceae › Dictyostelium |
Proteomesi |
|
Organism-specific databases
dictyBasei | DDB_G0291157, cln3 |
Subcellular locationi
Lysosome
- Lysosome membrane By similarity; Multi-pass membrane protein By similarity
Golgi apparatus
- Golgi apparatus Source: dictyBase
Lysosome
- lysosomal membrane Source: UniProtKB-SubCell
Vacuole
- contractile vacuole Source: dictyBase
- lysosomal membrane Source: UniProtKB-SubCell
- vacuole Source: GO_Central
Other locations
- endocytic vesicle Source: dictyBase
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 13 – 35 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 47 – 67 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 74 – 96 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 101 – 123 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 137 – 157 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 161 – 181 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 248 – 268 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 284 – 304 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 313 – 333 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 338 – 358 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 382 – 402 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Lysosome, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000328031 | 1 – 421 | BatteninAdd BLAST | 421 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 159 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 196 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 199 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 200 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 203 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q54F25 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 190 – 211 | DisorderedSequence analysisAdd BLAST | 22 |
Sequence similaritiesi
Belongs to the battenin family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG3880, Eukaryota |
HOGENOMi | CLU_029663_1_2_1 |
InParanoidi | Q54F25 |
OMAi | PYFIHRI |
PhylomeDBi | Q54F25 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR003492, Battenin_disease_Cln3 IPR036259, MFS_trans_sf |
PANTHERi | PTHR10981, PTHR10981, 1 hit |
Pfami | View protein in Pfam PF02487, CLN3, 1 hit |
PRINTSi | PR01315, BATTENIN |
SUPFAMi | SSF103473, SSF103473, 1 hit |
i Sequence
Sequence statusi: Complete.
Q54F25-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKDYTFIRN WISFHFMGNI NNFSYCVVNA ASGNLSAYFH NSKNIGIILW
60 70 80 90 100
ANIAFGLVSR LVNTFLIENV NSKLKIVVNC LFMSIGLIGV ALSVYVNFGF
110 120 130 140 150
CIAAIAFVGI ASSFGESVIL SYMKKFPAEL VNGWSSGTGI AGVCGSLFYI
160 170 180 190 200
AMVAAGLSNS TIFYMMLPTV AVYFLLFFFG LKVPNHLEED RTDNHNNSNN
210 220 230 240 250
SSNNSKYTEK QSLVKKDQLI EDIDDGGGAE VAPPGETKKQ RYIRCARLVW
260 270 280 290 300
FNAVNLALVY FFEYVASVGG ADLALKKDPN NDNFFIANAF AIFSFCYQLG
310 320 330 340 350
VLISRSSLQF VKIKHIGVIT ILQGINMVFW IIQAKYKMVT SVWVLFILMV
360 370 380 390 400
YCGLLGGASY VNVFYLILHQ KNIPNEDREL CINYAALLVT VGITLAACFI
410 420
LVMDHTFLAS EVPKTDSSSS T
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000175 Genomic DNA Translation: EAL61862.1 |
RefSeqi | XP_635365.1, XM_630273.1 |
Genome annotation databases
EnsemblProtistsi | EAL61862; EAL61862; DDB_G0291157 |
GeneIDi | 8628013 |
KEGGi | ddi:DDB_G0291157 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000175 Genomic DNA Translation: EAL61862.1 |
RefSeqi | XP_635365.1, XM_630273.1 |
3D structure databases
SMRi | Q54F25 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 44689.DDB0233983 |
Proteomic databases
PaxDbi | Q54F25 |
Genome annotation databases
EnsemblProtistsi | EAL61862; EAL61862; DDB_G0291157 |
GeneIDi | 8628013 |
KEGGi | ddi:DDB_G0291157 |
Organism-specific databases
dictyBasei | DDB_G0291157, cln3 |
Phylogenomic databases
eggNOGi | KOG3880, Eukaryota |
HOGENOMi | CLU_029663_1_2_1 |
InParanoidi | Q54F25 |
OMAi | PYFIHRI |
PhylomeDBi | Q54F25 |
Miscellaneous databases
PROi | PR:Q54F25 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR003492, Battenin_disease_Cln3 IPR036259, MFS_trans_sf |
PANTHERi | PTHR10981, PTHR10981, 1 hit |
Pfami | View protein in Pfam PF02487, CLN3, 1 hit |
PRINTSi | PR01315, BATTENIN |
SUPFAMi | SSF103473, SSF103473, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CLN3_DICDI | |
Accessioni | Q54F25Primary (citable) accession number: Q54F25 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 8, 2008 |
Last sequence update: | May 24, 2005 | |
Last modified: | February 23, 2022 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Dictyostelium discoideum
Dictyostelium discoideum: entries, gene names and cross-references to dictyBase - SIMILARITY comments
Index of protein domains and families