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Protein

Actin-binding protein F

Gene

abpF

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Actin-binding protein F
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:abpF
Synonyms:kenN
ORF Names:DDB_0230207
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0291229 abpF

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

  • Nucleus 1 Publication
  • cytoskeleton 1 Publication
  • Note: localizes at the centrosome.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003883731 – 2364Actin-binding protein FAdd BLAST2364

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q54ET6

PRoteomics IDEntifications database

More...
PRIDEi
Q54ET6

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with actin.

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q54ET6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1960 – 2017Sequence analysisAdd BLAST58
Coiled coili2129 – 2173Sequence analysisAdd BLAST45

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi152 – 158Poly-Ser7
Compositional biasi1412 – 1420Poly-Asn9
Compositional biasi1963 – 2014Lys-richAdd BLAST52
Compositional biasi2028 – 2035Poly-Thr8
Compositional biasi2038 – 2047Poly-Thr10

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JEHE Eukaryota
ENOG410YSC6 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q54ET6

Identification of Orthologs from Complete Genome Data

More...
OMAi
FVIEFIG

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q54ET6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVSNNKKFE ENYVLASDIE EKEKLLGTLI GGSPQYFYYN VIHLLNVDPT
60 70 80 90 100
LSDSKNREKY QKLMKDWSPE SKPIPVTPYG GNNNYESTQQ YKSVDLRQKL
110 120 130 140 150
LSFRQDNVNP SALANNVNDM FEELRYLLSL TFSYTQTTHQ TSPTTETTTT
160 170 180 190 200
PSSSSSSSHD DKSESTLDES LVNKKTVIES IINQYPYKVD YISPNSFEYV
210 220 230 240 250
LNNFTLPESA EKSIVQKLKY PIVPNDKLQQ LLSHHKGSFG SLKIHENLTL
260 270 280 290 300
EQMEKHIEKN PEHLDSAYVK LYLEKLLPTN ELHDWETLKP VQEQFYQSAS
310 320 330 340 350
KFVSNLPTSL NTFKLLIYHH YIKFQISDNK YDQSIIEKYF QLPRDTYYYV
360 370 380 390 400
EPDRLKSNPQ LSKFNDSFNG LKSVSQDDDE KLISFLLKKL FLKENSIKSY
410 420 430 440 450
QSYFRPNYLN LILAESKLLS NDSSPEKWIE MIDNHTKVQE LKDRVDIEFL
460 470 480 490 500
PTNREYYHPD DDVVIECAIK NVNTLLVKVF EISTFNYYKS ENKKIDSNIN
510 520 530 540 550
LDGLIASQEL SFDYSEQAPI EKVEKKFDFP NLKGKRGIFV IEFIGNGKSS
560 570 580 590 600
RSMIQKGDLH FIVETSPIGQ VIKIIDQDSI KVQKSSVYID GNAYNSNDDG
610 620 630 640 650
DIKIPFSSST SQKSIILMAK IGDSDVFASL KKFTHQSEHY SLSGGIFVEN
660 670 680 690 700
SSLLQNEKAP IVVRVKLFLG DTQISNNYLE EPSLTITSSD NSESPVVNSK
710 720 730 740 750
EIKPFALFDN KESVYQYKVQ EGLNSLTVRF EAKVRALSRN NNQETLSFES
760 770 780 790 800
TFQVNTINQT DQISEFYLER CLAKDGCSLG YQLCHLGKGG DPFSHLDVSM
810 820 830 840 850
DFQHWLTSER IYTTLKTDKN GKIHLGSLAD IEQLNVNGSY ATFNFPIKRQ
860 870 880 890 900
QQFTYPSQIN IKLGETIRLP YLGNEKSVSH SQINFFQLGG VDDRNFVVHD
910 920 930 940 950
LLKKSVTIEN KNELLINGLG VGRYLLILAG SIQSSNTVEI LIDVVDGQFR
960 970 980 990 1000
EGYLVGPSRI VSYNESNVKS LFFDTNIDTK HNQLQVKFKN HSPSTRVHVF
1010 1020 1030 1040 1050
SSYFEPTNSL NSSLSLSRGT SQSYQEYSVK PKSLYFNGRS LGDEVNYILN
1060 1070 1080 1090 1100
RKTSKKLLPG NSLKKPSLLV QPWSIGKTTN STNTLKQASK YNESEVKDEK
1110 1120 1130 1140 1150
SMRNRQVEKR RVSSTNRSPF LEFLSHPSIL LLNLEPSSTD GIVNIDLSQL
1160 1170 1180 1190 1200
VEAGSTIHIH AVDNDSIFTK EIVISDPSSS SSINHFKDTK LVRPLDSSLH
1210 1220 1230 1240 1250
YKEEKLITTV EPNSPFEILN VNSSKYTVYD SLDKVLSLMK TLNKSYLQDF
1260 1270 1280 1290 1300
SFIAEWESLS FEKKKEKFSK FTCHELNFFI YKKDKEFFDQ VVLPLVQTKG
1310 1320 1330 1340 1350
YKTFIDHYLC ADRKKLEIFV IDSNRFNTLN ALEMVLLGEL FPEHSDSISN
1360 1370 1380 1390 1400
LLKQKVGFSP ISPSQYDTNF KIALNQLDTD IESLKSGDDD LYDDGSNLEP
1410 1420 1430 1440 1450
MSVGGGGGFG YNNNSNNNNN TTNSNSFGDA KRAPMKKKMV NKESTSLMMD
1460 1470 1480 1490 1500
CAAPMMMMAS APCPAPGAVP MAALRSARLA SASPAPPAPI TRAYEAAQIY
1510 1520 1530 1540 1550
QPIEKTEELA ETYYYKQLNP HSSLIPVNEF WLDYANHIKS QSKTPFVSKY
1560 1570 1580 1590 1600
IAFISSSFAE SMMALSVLDF PFTVKDNTTQ VRPKNGKLSM KPTTPIVVFH
1610 1620 1630 1640 1650
QELVSGSIEK QSDILVTQHF FDPQNQFTYI DGEQEELYIN DQFLVSKVYG
1660 1670 1680 1690 1700
AMVVIANLSS KQKKLDALLE IPKGSIAVGP SPFVTRSKSV NLSAYSTTRL
1710 1720 1730 1740 1750
QYYFYFPEAG KFPHFPAHVS EKQNIIANVT PFTFSVVLKP SIVNHLSWEY
1760 1770 1780 1790 1800
IANQGTLESI LEYLSKNNLY RVDFYHLYHR YTDKKVWDKV IELLKKLKFY
1810 1820 1830 1840 1850
ESITWSFSIH HKNFVYLKDY LSEQIHSLSM KSIDAPSIYV DPFENNFIKF
1860 1870 1880 1890 1900
LEYSPLVNSR THQIGDERKI LNNKLSNQYY EFCSLLSLKL NPSDTELLSL
1910 1920 1930 1940 1950
AYYLLLQDRF DESIKIMKRI GKHPVSIPKL ISSSTTTDSK STHSSVISSS
1960 1970 1980 1990 2000
SSSNLSTTTD SSKDKKKLEK EEKQREKERK QKEKEDKKRE KEELKKKEKE
2010 2020 2030 2040 2050
EKKKKEEEKK LKKKSGSEAT SPSVDPATPT TTTTTEATTT TTTTTATSQE
2060 2070 2080 2090 2100
SIKPEKIASD DEHDDHHHDE HDEEDDDDEP LIDMSEFNQP SCLPEMKVQY
2110 2120 2130 2140 2150
DYLLSYLDFF NPNPTVAAEN SKKYENYPVQ RWNSLFKDLR NKVDQVSNKD
2160 2170 2180 2190 2200
SVEIDYEKEI DRERRQNKMA SNEPTFDISS ESNRTISVNY SNLVDITVSY
2210 2220 2230 2240 2250
YVMDIEHLFS TNPFVQQELG HFLYVTPNKK ESFLLKDKSG TFNFKIPNEF
2260 2270 2280 2290 2300
ANSNVVIDVV SAQIHHNITV YSNNLAVYIT EKVGQLRVVH KQKSQPISKT
2310 2320 2330 2340 2350
YIKVYSKNKN GSVEFFKDGY TDIAGYFDYS TVSSLDISNV SKLSILVLSN
2360
QYGAVIKEAK PPGF
Length:2,364
Mass (Da):269,778
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i64C12F4868180943
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000177 Genomic DNA Translation: EAL61598.1

NCBI Reference Sequences

More...
RefSeqi
XP_635154.1, XM_630062.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL61598; EAL61598; DDB_G0291229

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8628100

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0291229

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000177 Genomic DNA Translation: EAL61598.1
RefSeqiXP_635154.1, XM_630062.1

3D structure databases

SMRiQ54ET6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ54ET6
PRIDEiQ54ET6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL61598; EAL61598; DDB_G0291229
GeneIDi8628100
KEGGiddi:DDB_G0291229

Organism-specific databases

dictyBaseiDDB_G0291229 abpF

Phylogenomic databases

eggNOGiENOG410JEHE Eukaryota
ENOG410YSC6 LUCA
InParanoidiQ54ET6
OMAiFVIEFIG

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q54ET6

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiABPF_DICDI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q54ET6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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