Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 97 (02 Jun 2021)
Sequence version 1 (24 May 2005)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

DDB0219853

Organism
Dictyostelium discoideum (Slime mold)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingARBA annotation
Biological processDNA recombinationARBA annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DDI-5693616, Presynaptic phase of homologous DNA pairing and strand exchange

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:DDB0219853Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyosteliaDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0293414

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q54BU8

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0219853

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini703 – 775BRCA-2_helicalInterPro annotationAdd BLAST73
Domaini779 – 987BRCA-2_OB1InterPro annotationAdd BLAST209

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 53DisorderedSequence analysisAdd BLAST53
Regioni85 – 167DisorderedSequence analysisAdd BLAST83
Regioni213 – 338DisorderedSequence analysisAdd BLAST126
Regioni381 – 653DisorderedSequence analysisAdd BLAST273
Regioni811 – 833DisorderedSequence analysisAdd BLAST23
Regioni854 – 901DisorderedSequence analysisAdd BLAST48
Regioni1211 – 1231DisorderedSequence analysisAdd BLAST21
Regioni1562 – 1600DisorderedSequence analysisAdd BLAST39

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili755 – 775Sequence analysisAdd BLAST21
Coiled coili1038 – 1066Sequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 22Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi23 – 47Polar residuesSequence analysisAdd BLAST25
Compositional biasi90 – 147Polar residuesSequence analysisAdd BLAST58
Compositional biasi214 – 338Polar residuesSequence analysisAdd BLAST125
Compositional biasi382 – 648Polar residuesSequence analysisAdd BLAST267
Compositional biasi1562 – 1599Polar residuesSequence analysisAdd BLAST38

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4751, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_243471_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q54BU8

Identification of Orthologs from Complete Genome Data

More...
OMAi
GFKTGRN

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015525, BRCA2
IPR015252, BRCA2_hlx
IPR036315, BRCA2_hlx_sf
IPR015187, BRCA2_OB_1
IPR012340, NA-bd_OB-fold

The PANTHER Classification System

More...
PANTHERi
PTHR11289, PTHR11289, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09169, BRCA-2_helical, 1 hit
PF09103, BRCA-2_OB1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50249, SSF50249, 2 hits
SSF81872, SSF81872, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q54BU8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKSNSNKREF SSDDDNSNVE SDSSKKTRIS PPSTPQPQTT TSLIPPPVFK
60 70 80 90 100
GFSTGRGAAV VISEEKLRLA KKKLSSIGDE DIKDLLPSES GAVDNSNDFL
110 120 130 140 150
TMTNSNSNNN SNSNNNDTIN TTATITPTTT SSSPLLQTTT TSSSLSSSSP
160 170 180 190 200
PPPLPQTTTS SIPPTFKGFS TGRGVAVVIS EEKLKLAQKK LSSIADEDIK
210 220 230 240 250
DLLPSEGGVV DNNDFLAMNS SSNNSNGSNN NNNNNNNNNN NNNNNNNNNN
260 270 280 290 300
NNNNNNNNTT TTTASSSSSS SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS
310 320 330 340 350
SSSSSSSSSS PSLQTTTSSS PPQLLQTTTS SIPTTFKGFS TGRGVAVVIS
360 370 380 390 400
EEKLKLAQKK LSSIADEDIK DLLPSEGGAV DNNDFLTMNN SNSNNSNSSH
410 420 430 440 450
TNTTTTTTTT TTNTTNTTTA STSNDNSTSR SDDSSAPSSP QPQQNIRAPS
460 470 480 490 500
PPSSFSSSSS TSSIAPPTTP NRSPVPTSTN LNSSTATVPQ LTTPTKSKYP
510 520 530 540 550
LQSPVKKTFV YNPNTTPTKK SFIPPTKSLS PPQQQQTSTV PPQTNIAPTT
560 570 580 590 600
TSTFSYPTTP KTAPKILSKP QISTPKKSSF KPPIKSNNTP TTPTTTTTST
610 620 630 640 650
TISPASPNGN SKGISPPKSK LNISPSKSTT PINNNNNTNN NNNNNIQKKP
660 670 680 690 700
IDNRRKLKDL GRPFLVSCEG LVKNDVLEIT SRNASEYRFE NNGEVKDIGK
710 720 730 740 750
SKTIGVADLY IYLTKINQSN AALVSQEWVS NHYGWIVWKL ASMERSFPLE
760 770 780 790 800
FGGKYLKLQR VVNQLKQRIE IEINQAKRPI LKKIYERDQP SELPMVLCIS
810 820 830 840 850
SILDDGYGGG INNNNNPNNP NNNNNNNNCT VENDDGIISM DDIDITMNDD
860 870 880 890 900
LETASTSTTI SSTNNANNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNKT
910 920 930 940 950
NYIQHPIATI ELTDGWYPIK GALDPFLTQC LKQGKLFVGQ KLYIQNAGIV
960 970 980 990 1000
GQENGISPLE DGFEQVHLKL FTNSTRRVSW YENLGARKSM FPISLKSIIP
1010 1020 1030 1040 1050
GGGTVACLKV EVTHIYKLSF KETIMGEDGS LKTVITRCEN EEQQYKQQYE
1060 1070 1080 1090 1100
SKAEIAREKL LESTSKQLEK KQKEDILMSS LQEQQQQKLK GKLLPNQQNR
1110 1120 1130 1140 1150
VRKIPQSALD QKINHKTISN LSEISDGDSL YAYFLRVIDQ EGFVDCLSDE
1160 1170 1180 1190 1200
QKSLLFSNRD KQYQSLQQQI LDQVDDEMNS NPNFKTRNVK PILSIKIRDL
1210 1220 1230 1240 1250
LIKNDIDQLN NNNPNNINNN NNNNNNPNND YNNILDDDFN NNCNNETILS
1260 1270 1280 1290 1300
IESPSYDLMD TLKESMKLTL HMVNPKKMFY SPFRPTGLSP LQSSHRFNVV
1310 1320 1330 1340 1350
PIIDNNIGGG GSGNSQKNLN TNGLHKKGIQ RLDQFLINGN SIGSECDLVV
1360 1370 1380 1390 1400
FILYVGDIKV EETLIKDRKR IDSSRFIYFT DRSGFIGRIN ITKTTWTTGI
1410 1420 1430 1440 1450
TNENGGGGSG SSLINQNNQI YFPFKTGFTL SDSQSNNDNL SSHNLLNPFM
1460 1470 1480 1490 1500
VNNNNNNLPI IHLSNLIFKG VDSNQILLFD GSEFFEHSVK PKSKNIVDLF
1510 1520 1530 1540 1550
DDLKQFIKSS PGLLNLFCFR VNSILNQLST PSQINNIKYN SYSTNSNSNN
1560 1570 1580 1590 1600
KIIEKNSLVN STSNQVNKNN NNNNNNNINN NNNNNIINSN NNEPDEMPSS
1610 1620
QDFNFDFDPV FLENSGILFF IIF
Length:1,623
Mass (Da):177,864
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i53731E94F2FCFEBD
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI01000282 Genomic DNA Translation: EAL60741.1

NCBI Reference Sequences

More...
RefSeqi
XP_629153.1, XM_629151.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8629210

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0293414

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI01000282 Genomic DNA Translation: EAL60741.1
RefSeqiXP_629153.1, XM_629151.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi44689.DDB0219853

Proteomic databases

PaxDbiQ54BU8

Genome annotation databases

GeneIDi8629210
KEGGiddi:DDB_G0293414

Organism-specific databases

dictyBaseiDDB_G0293414

Phylogenomic databases

eggNOGiKOG4751, Eukaryota
HOGENOMiCLU_243471_0_0_1
InParanoidiQ54BU8
OMAiGFKTGRN

Enzyme and pathway databases

ReactomeiR-DDI-5693616, Presynaptic phase of homologous DNA pairing and strand exchange

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q54BU8

Family and domain databases

InterProiView protein in InterPro
IPR015525, BRCA2
IPR015252, BRCA2_hlx
IPR036315, BRCA2_hlx_sf
IPR015187, BRCA2_OB_1
IPR012340, NA-bd_OB-fold
PANTHERiPTHR11289, PTHR11289, 2 hits
PfamiView protein in Pfam
PF09169, BRCA-2_helical, 1 hit
PF09103, BRCA-2_OB1, 1 hit
SUPFAMiSSF50249, SSF50249, 2 hits
SSF81872, SSF81872, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ54BU8_DICDI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q54BU8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: June 2, 2021
This is version 97 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again