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UniProtKB - Q54B60 (OMT11_DICDI)
Protein
Probable inactive O-methyltransferase 11
Gene
omt11
Organism
Dictyostelium discoideum (Slime mold)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 179 | S-adenosyl-L-methionine; via carbonyl oxygenPROSITE-ProRule annotation | 1 | |
Binding sitei | 202 | S-adenosyl-L-methioninePROSITE-ProRule annotation | 1 | |
Binding sitei | 225 | S-adenosyl-L-methioninePROSITE-ProRule annotation | 1 | |
Binding sitei | 226 | S-adenosyl-L-methionine; via amide nitrogenPROSITE-ProRule annotation | 1 | |
Binding sitei | 239 | S-adenosyl-L-methioninePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- O-methyltransferase activity Source: GO_Central
- S-adenosylmethionine-dependent methyltransferase activity Source: GO_Central
GO - Biological processi
- aromatic compound biosynthetic process Source: GO_Central
- methylation Source: GO_Central
Keywordsi
Molecular function | Methyltransferase, Transferase |
Ligand | S-adenosyl-L-methionine |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:omt11 ORF Names:DDB_G0293886 |
Organismi | Dictyostelium discoideum (Slime mold) |
Taxonomic identifieri | 44689 [NCBI] |
Taxonomic lineagei | Eukaryota › Amoebozoa › Evosea › Eumycetozoa › Dictyostelia › Dictyosteliales › Dictyosteliaceae › Dictyostelium |
Proteomesi |
|
Organism-specific databases
dictyBasei | DDB_G0293886, omt11 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000363971 | 1 – 331 | Probable inactive O-methyltransferase 11Add BLAST | 331 |
Proteomic databases
PaxDbi | Q54B60 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 224 – 226 | S-adenosyl-L-methionine bindingPROSITE-ProRule annotation | 3 |
Sequence similaritiesi
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.PROSITE-ProRule annotation
Phylogenomic databases
eggNOGi | KOG3178, Eukaryota |
HOGENOMi | CLU_005533_12_0_1 |
InParanoidi | Q54B60 |
OMAi | CVEILAN |
PhylomeDBi | Q54B60 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR016461, COMT-like IPR001077, O_MeTrfase_dom IPR029063, SAM-dependent_MTases IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR11746, PTHR11746, 1 hit |
Pfami | View protein in Pfam PF00891, Methyltransf_2, 1 hit |
PIRSFi | PIRSF005739, O-mtase, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF53335, SSF53335, 1 hit |
PROSITEi | View protein in PROSITE PS51683, SAM_OMT_II, 1 hit |
i Sequence
Sequence statusi: Complete.
Q54B60-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MECSESLELV DKFACGHILS RMFNVVMKHS ICDLLEDGPK HYSEISKIIG
60 70 80 90 100
FKDDSYCYRL MRYFVPRKLF KESVVQVGVF SKTPFSTEFS NNGTLKKLAK
110 120 130 140 150
FHCNSFHYKL SQVLPETLEI GENQGPSSIG LSDYWEQIEK NEIYKNEFND
160 170 180 190 200
GMIGYTTHIL KFLKGKIDLS KFETVVDIGG SHGYLIGSLL DRYPNVNGIN
210 220 230 240 250
FDTDMVINSS NEKYQHPRLK HVAGDFFKSV PEADCYLMKL ILRCFSDEKC
260 270 280 290 300
CELLKIISKS MKSNAKIIIL DIILDSSKYL NFDTYLDILM METLDGKQRS
310 320 330
LSEWIKLFEM SGFKIDKYES GSPNYLIISK E
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000223 Genomic DNA Translation: EAL60514.1 |
RefSeqi | XP_628928.1, XM_628926.1 |
Genome annotation databases
EnsemblProtistsi | EAL60514; EAL60514; DDB_G0293886 |
GeneIDi | 8629470 |
KEGGi | ddi:DDB_G0293886 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000223 Genomic DNA Translation: EAL60514.1 |
RefSeqi | XP_628928.1, XM_628926.1 |
3D structure databases
SMRi | Q54B60 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 44689.DDB0231349 |
Proteomic databases
PaxDbi | Q54B60 |
Genome annotation databases
EnsemblProtistsi | EAL60514; EAL60514; DDB_G0293886 |
GeneIDi | 8629470 |
KEGGi | ddi:DDB_G0293886 |
Organism-specific databases
dictyBasei | DDB_G0293886, omt11 |
Phylogenomic databases
eggNOGi | KOG3178, Eukaryota |
HOGENOMi | CLU_005533_12_0_1 |
InParanoidi | Q54B60 |
OMAi | CVEILAN |
PhylomeDBi | Q54B60 |
Miscellaneous databases
PROi | PR:Q54B60 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR016461, COMT-like IPR001077, O_MeTrfase_dom IPR029063, SAM-dependent_MTases IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR11746, PTHR11746, 1 hit |
Pfami | View protein in Pfam PF00891, Methyltransf_2, 1 hit |
PIRSFi | PIRSF005739, O-mtase, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF53335, SSF53335, 1 hit |
PROSITEi | View protein in PROSITE PS51683, SAM_OMT_II, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | OMT11_DICDI | |
Accessioni | Q54B60Primary (citable) accession number: Q54B60 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 10, 2009 |
Last sequence update: | May 24, 2005 | |
Last modified: | February 23, 2022 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Dictyostelium discoideum
Dictyostelium discoideum: entries, gene names and cross-references to dictyBase - SIMILARITY comments
Index of protein domains and families