UniProtKB - Q545S4 (Q545S4_MOUSE)
Protein
Stathmin
Gene
Stmn2
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- calcium-dependent protein binding Source: Ensembl
GO - Biological processi
- cellular response to nerve growth factor stimulus Source: Ensembl
- negative regulation of microtubule depolymerization Source: Ensembl
- negative regulation of microtubule polymerization Source: Ensembl
- negative regulation of neuron projection development Source: Ensembl
- positive regulation of microtubule depolymerization Source: Ensembl
- positive regulation of neuron projection development Source: Ensembl
Names & Taxonomyi
Protein namesi | Recommended name: StathminUniRule annotation |
Gene namesi | Name:Stmn2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:98241, Stmn2 |
Subcellular locationi
Other locations
- lamellipodium ARBA annotation
- Cytoplasm ARBA annotation
- Membrane ARBA annotation; Peripheral membrane protein ARBA annotation; Cytoplasmic side ARBA annotation
Golgi apparatus
- Golgi apparatus Source: Ensembl
Other locations
- growth cone Source: Ensembl
- lamellipodium Source: UniProtKB-SubCell
- membrane Source: UniProtKB-SubCell
- neuronal cell body Source: Ensembl
- perinuclear region of cytoplasm Source: Ensembl
- vesicle Source: Ensembl
Keywords - Cellular componenti
Cell projectionARBA annotation, CytoplasmARBA annotation, MembraneARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000027500, Expressed in Ammon's horn and 291 other tissues |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 81 – 123 | Sequence analysisAdd BLAST | 43 | |
Coiled coili | 143 – 170 | Sequence analysisAdd BLAST | 28 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisARBA annotationPhylogenomic databases
HOGENOMi | CLU_102026_0_0_1 |
OMAi | CFYPEAR |
OrthoDBi | 1381987at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR026729, Stathmin-2 IPR030514, Stathmin_CS IPR000956, Stathmin_fam IPR036002, Stathmin_sf |
PANTHERi | PTHR10104, PTHR10104, 1 hit PTHR10104:SF18, PTHR10104:SF18, 1 hit |
Pfami | View protein in Pfam PF00836, Stathmin, 1 hit |
PIRSFi | PIRSF002285, Stathmin, 1 hit |
PRINTSi | PR00345, STATHMIN |
SUPFAMi | SSF101494, SSF101494, 1 hit |
PROSITEi | View protein in PROSITE PS00563, STATHMIN_1, 1 hit PS01041, STATHMIN_2, 1 hit PS51663, STATHMIN_3, 1 hit |
i Sequence
Sequence statusi: Complete.
Q545S4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKTAMAYKE KMKELSMLSL ICSCFYPEPR NINIYTYDDM EVKQINKRAS
60 70 80 90 100
GQAFELILKP PSPISEAPRT LASPKKKDLS LEEIQKKLEA AEERRKSQEA
110 120 130 140 150
QVLKQLAEKR EHEREVLQKA LEENNNFSKM AEEKLILKME QIKENREANL
160 170
AAIIERLQEK ERHAAEVRRN KELQVELSG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK003659 mRNA Translation: BAB22921.1 AK149212 mRNA Translation: BAE28766.1 |
RefSeqi | NP_079561.1, NM_025285.2 |
Genome annotation databases
GeneIDi | 20257 |
KEGGi | mmu:20257 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK003659 mRNA Translation: BAB22921.1 AK149212 mRNA Translation: BAE28766.1 |
RefSeqi | NP_079561.1, NM_025285.2 |
3D structure databases
SMRi | Q545S4 |
ModBasei | Search... |
Proteomic databases
EPDi | Q545S4 |
MaxQBi | Q545S4 |
Protocols and materials databases
Antibodypediai | 6337, 425 antibodies |
Genome annotation databases
GeneIDi | 20257 |
KEGGi | mmu:20257 |
Organism-specific databases
CTDi | 11075 |
MGIi | MGI:98241, Stmn2 |
Phylogenomic databases
HOGENOMi | CLU_102026_0_0_1 |
OMAi | CFYPEAR |
OrthoDBi | 1381987at2759 |
Miscellaneous databases
BioGRID-ORCSi | 20257, 1 hit in 17 CRISPR screens |
ChiTaRSi | Stmn2, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000027500, Expressed in Ammon's horn and 291 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR026729, Stathmin-2 IPR030514, Stathmin_CS IPR000956, Stathmin_fam IPR036002, Stathmin_sf |
PANTHERi | PTHR10104, PTHR10104, 1 hit PTHR10104:SF18, PTHR10104:SF18, 1 hit |
Pfami | View protein in Pfam PF00836, Stathmin, 1 hit |
PIRSFi | PIRSF002285, Stathmin, 1 hit |
PRINTSi | PR00345, STATHMIN |
SUPFAMi | SSF101494, SSF101494, 1 hit |
PROSITEi | View protein in PROSITE PS00563, STATHMIN_1, 1 hit PS01041, STATHMIN_2, 1 hit PS51663, STATHMIN_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q545S4_MOUSE | |
Accessioni | Q545S4Primary (citable) accession number: Q545S4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 24, 2005 |
Last sequence update: | May 24, 2005 | |
Last modified: | December 2, 2020 | |
This is version 133 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |