UniProtKB - Q542X5 (Q542X5_MOUSE)
Protein
Submitted name:
Uncharacterized protein
Gene
Efemp2
Organism
Mus musculus (Mouse)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Molecular functioni
- calcium ion binding Source: InterPro
GO - Biological processi
- elastic fiber assembly Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:Efemp2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1891209, Efemp2 |
Subcellular locationi
Extracellular region or secreted
- extracellular space Source: InterPro
PTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 207 ↔ 217 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondPROSITE-ProRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000024909, Expressed in humerus cartilage element and 252 other tissues |
ExpressionAtlasi | Q542X5, baseline and differential |
Family & Domainsi
Keywords - Domaini
EGF-like domainPROSITE-ProRule annotationARBA annotation, SignalARBA annotationPhylogenomic databases
HOGENOMi | CLU_004826_0_1_1 |
OMAi | QQCHNLP |
OrthoDBi | 1174178at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR026823, cEGF IPR026824, Efemp2 IPR001881, EGF-like_Ca-bd_dom IPR000742, EGF-like_dom IPR000152, EGF-type_Asp/Asn_hydroxyl_site IPR018097, EGF_Ca-bd_CS IPR009030, Growth_fac_rcpt_cys_sf |
PANTHERi | PTHR24034:SF96, PTHR24034:SF96, 1 hit |
Pfami | View protein in Pfam PF12662, cEGF, 2 hits PF07645, EGF_CA, 3 hits |
SMARTi | View protein in SMART SM00181, EGF, 5 hits SM00179, EGF_CA, 6 hits |
SUPFAMi | SSF57184, SSF57184, 3 hits |
PROSITEi | View protein in PROSITE PS00010, ASX_HYDROXYL, 4 hits PS01186, EGF_2, 3 hits PS50026, EGF_3, 4 hits PS01187, EGF_CA, 2 hits |
i Sequence
Sequence statusi: Complete.
Q542X5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLPFASCLPG SLLLWAFLLL LLGAASPQDP EEPDSYTECT DGYEWDADSQ
60 70 80 90 100
HCRDVNECLT IPEACKGEMK CINHYGGYLC LPRSAAVISD LHGEGPPPPA
110 120 130 140 150
AHAQQPNPCP QGYEPDEQES CVDVDECTQA LHDCRPSQDC HNLPGSYQCT
160 170 180 190 200
CPDGYRKIGP ECVDIDECRY RYCQHRCVNL PGSFRCQCEP GFQLGPNNRS
210 220 230 240 250
CVDVNECDMG APCEQRCFNS YGTFLCRCNQ GYELHRDGFS CSDIDECGYS
260 270 280 290 300
SYLCQYRCVN EPGRFSCHCP QGYQLLATRL CQDIDECETG AHQCSEAQTC
310 320 330 340 350
VNFHGGYRCV DTNRCVEPYV QVSDNRCLCP ASNPLCREQP SSIVHRYMSI
360 370 380 390 400
TSERSVPADV FQIQATSVYP GAYNAFQIRS GNTQGDFYIR QINNVSAMLV
410 420 430 440
LARPVTGPRE YVLDLEMVTM NSLMSYRASS VLRLTVFVGA YTF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK075585 mRNA Translation: BAC35838.1 |
RefSeqi | NP_001157824.1, NM_001164352.1 NP_067449.3, NM_021474.3 XP_006531871.1, XM_006531808.1 |
Genome annotation databases
GeneIDi | 58859 |
KEGGi | mmu:58859 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK075585 mRNA Translation: BAC35838.1 |
RefSeqi | NP_001157824.1, NM_001164352.1 NP_067449.3, NM_021474.3 XP_006531871.1, XM_006531808.1 |
3D structure databases
SMRi | Q542X5 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 16033, 359 antibodies |
Genome annotation databases
GeneIDi | 58859 |
KEGGi | mmu:58859 |
Organism-specific databases
CTDi | 30008 |
MGIi | MGI:1891209, Efemp2 |
Phylogenomic databases
HOGENOMi | CLU_004826_0_1_1 |
OMAi | QQCHNLP |
OrthoDBi | 1174178at2759 |
Miscellaneous databases
BioGRID-ORCSi | 58859, 5 hits in 17 CRISPR screens |
ChiTaRSi | Efemp2, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000024909, Expressed in humerus cartilage element and 252 other tissues |
ExpressionAtlasi | Q542X5, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR026823, cEGF IPR026824, Efemp2 IPR001881, EGF-like_Ca-bd_dom IPR000742, EGF-like_dom IPR000152, EGF-type_Asp/Asn_hydroxyl_site IPR018097, EGF_Ca-bd_CS IPR009030, Growth_fac_rcpt_cys_sf |
PANTHERi | PTHR24034:SF96, PTHR24034:SF96, 1 hit |
Pfami | View protein in Pfam PF12662, cEGF, 2 hits PF07645, EGF_CA, 3 hits |
SMARTi | View protein in SMART SM00181, EGF, 5 hits SM00179, EGF_CA, 6 hits |
SUPFAMi | SSF57184, SSF57184, 3 hits |
PROSITEi | View protein in PROSITE PS00010, ASX_HYDROXYL, 4 hits PS01186, EGF_2, 3 hits PS50026, EGF_3, 4 hits PS01187, EGF_CA, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q542X5_MOUSE | |
Accessioni | Q542X5Primary (citable) accession number: Q542X5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 24, 2005 |
Last sequence update: | May 24, 2005 | |
Last modified: | February 10, 2021 | |
This is version 146 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |