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Entry version 117 (29 Sep 2021)
Sequence version 1 (24 May 2005)
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Protein

GTSE1_N domain-containing protein

Gene

Gtse1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
GTSE1_N domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Gtse1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

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MGIi
MGI:1352755, Gtse1

Eukaryotic Pathogen, Vector and Host Database Resources

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VEuPathDBi
HostDB:ENSMUSG00000022385

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q542Q3

PeptideAtlas

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PeptideAtlasi
Q542Q3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000022385, Expressed in secondary oocyte and 162 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q542Q3, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q542Q3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 153GTSE1_NInterPro annotationAdd BLAST144

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni101 – 120DisorderedSequence analysisAdd BLAST20
Regioni131 – 428DisorderedSequence analysisAdd BLAST298
Regioni450 – 512DisorderedSequence analysisAdd BLAST63
Regioni550 – 640DisorderedSequence analysisAdd BLAST91

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi174 – 214Polar residuesSequence analysisAdd BLAST41
Compositional biasi250 – 265Polar residuesSequence analysisAdd BLAST16
Compositional biasi304 – 359Polar residuesSequence analysisAdd BLAST56
Compositional biasi391 – 409Polar residuesSequence analysisAdd BLAST19
Compositional biasi469 – 512Polar residuesSequence analysisAdd BLAST44
Compositional biasi563 – 616Polar residuesSequence analysisAdd BLAST54

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_023558_0_0_1

Identification of Orthologs from Complete Genome Data

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OMAi
PSRTKIP

Database of Orthologous Groups

More...
OrthoDBi
1407808at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q542Q3

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026657, DDA3/GTSE-1
IPR026659, GTSE1
IPR032768, GTSE1_N

The PANTHER Classification System

More...
PANTHERi
PTHR21584, PTHR21584, 1 hit
PTHR21584:SF10, PTHR21584:SF10, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15259, GTSE1_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q542Q3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAGSKKEDF LLLEDEKFDF DLSLSSSSTN EDDEVFFGPV GHKERCIAAS
60 70 80 90 100
LDLNRRVPGQ PLAPGSGSPC TLSPLTGEKF VEVYKEAHLL ALQIESHSRR
110 120 130 140 150
EVAQAATPQN PVNQGKETFV QDSQLKVSLF EKEQKRDRSP MSLKRETFCL
160 170 180 190 200
PSSRVQPPMG EPQLLASPGL LSSPVSAGPA QTQSNQGLPC SSQPLPRESS
210 220 230 240 250
TSQPPSQAGP QKRITSKLQP PRALPVRGRN LHLATEKLKK EVPASIQRTK
260 270 280 290 300
LVNEKGSQSD VLQDKPSTAP DAASREGHPG KRSLPIPGKL GLKKTLLKPP
310 320 330 340 350
GYTGNLTRKS STSGSASSLE SGVYRSSVAG KAKSSEQRSS IPASGSQRRT
360 370 380 390 400
STSKSGRIGP AASRQALPAA PARVFGRQAN KADAAQTVAE QPKVPTLSPL
410 420 430 440 450
TQQPQTPEQR GPRLDPDTET PQLNKTVSIK RRDSYLSCKT EAVSTTTNPF
460 470 480 490 500
KVPQFSVGES PGGVTPKFSR THRLQSWTPA SRVVSSTPVR RSSGTTPQGL
510 520 530 540 550
PGSMRTPLST RRMSVLPTPA SRRLSSLPLM APQSMPRALV SPLCVPARRL
560 570 580 590 600
SSEPRRRSTV RAELTQESSG SGSGGQAQGL SSDESSSPPS SVPQALNFSP
610 620 630 640 650
EKSASPPPQG SSTGAAQGEA EPPEDTLPSE VHGGGCSHTP SEGLLLDLKL
660 670 680 690 700
DQLTITPEAG GRDLADCPLI DFSNTPESNT ALGPSSWPLI DLIMNTPDMG
710 720 730 740
RNDVGKPAKA ELGQLIDLGS PLIQLSPEAD KENVDSPLLK F
Length:741
Mass (Da):78,751
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1C684D06EE9B7ACB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK081582 mRNA Translation: BAC38262.1

NCBI Reference Sequences

More...
RefSeqi
NP_001162143.1, NM_001168672.1
NP_038910.1, NM_013882.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
29870

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:29870

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK081582 mRNA Translation: BAC38262.1
RefSeqiNP_001162143.1, NM_001168672.1
NP_038910.1, NM_013882.2

3D structure databases

SMRiQ542Q3
ModBaseiSearch...

Proteomic databases

EPDiQ542Q3
PeptideAtlasiQ542Q3

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
28047, 263 antibodies

The DNASU plasmid repository

More...
DNASUi
29870

Genome annotation databases

GeneIDi29870
KEGGimmu:29870

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51512
MGIiMGI:1352755, Gtse1
VEuPathDBiHostDB:ENSMUSG00000022385

Phylogenomic databases

HOGENOMiCLU_023558_0_0_1
OMAiPSRTKIP
OrthoDBi1407808at2759
PhylomeDBiQ542Q3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
29870, 9 hits in 64 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Gtse1, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000022385, Expressed in secondary oocyte and 162 other tissues
ExpressionAtlasiQ542Q3, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR026657, DDA3/GTSE-1
IPR026659, GTSE1
IPR032768, GTSE1_N
PANTHERiPTHR21584, PTHR21584, 1 hit
PTHR21584:SF10, PTHR21584:SF10, 1 hit
PfamiView protein in Pfam
PF15259, GTSE1_N, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ542Q3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q542Q3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 29, 2021
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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