>tr|Q54296|Q54296_STRHY Polyketide synthase OS=Streptomyces hygroscopicus OX=1912 GN=rapB PE=4 SV=1
MREDQLLDALRKSVKENARLRKANTSLRAAMDEPLAIVGMACRLPGGVSSPEDLWRLVES
GTDAISGFPADRGWDVENLYDPDPEAAGKSYCVQGGFLDSAGGFDASFFGISPREALAMD
PQQRLVLEASWEAFERAGIEPGSLRGSDTGVFMGAYPGGYGVGADLGGFGATAGAVSVLS
GRVSYFFGLEGPAVTVDTACSSSLVALHQAAYALRQGECSLALVGGVTVMATPQSFVEFS
RQRGLASDGRCKAFADSADGTGWAEGAGVLLVERLSDAQRKGHQVLAVVRGSAVNQDGAS
NGLSAPNGPSQQRVIRAALSNAGLSTAEVDVVEAHGTGTTLGDPIEAQALLATYGQDREQ
PLLLGSVKSNLGHTQAAAGVSGVIKMVMALQHVLVPRTLHVDEPSRHVDWTDGAVALVTE
NQPWPDMGRPRRAGVSSFGISGTNAHVILESAPPTQAVDDVPPAEAPVVASELVPLVISA
RTLPALVEYEDRLRAYLAASPGVDVRGVASTLAVTRSVFEHRAVLLGDDTVTGTTVSDPR
VVFVFPGQGSQRAGMGEELAAAFPVFARIHQQVWGLLDVPDLEVNETGYAQPALFALQVA
LFGLLESWGVRPDAVVGHSVGELAAGYVSGLWSLEDACTLVSARARLMQALPPGGVMVAV
PVSEDEARAVLGEGVEIAAVNGPSSVVLSGDETAVLQAAAALGKSTRLATSHAFHSARME
PMLEEFRTVAERLTYQTPRLAMAAGDRVTTAEYWVRQVRDTVRFGEQVASYEDAVFIELG
ADRSLARLVDGVAMLHTDHEAQAAISALAHLYVNGVTVDWTALLGDAPATRVLDLPTYAF
QHQRYWLEGADRAAAGGHPLLGPAVGLAEASGVLFTSQVSRSGDLWLQDQTVLPATAFAE
MALAAADETGCGLVEELTVEALLLLPDDGAVQVQTWVSEPDDAGRRQLSIHARYSDDELW
TRLATATLATTTGRVSGWQAGEAWPPAGAVPVEARVPSLRGVWRRGSEVFAEVALDDTHD
ATRFLLHPGLMTAAFAAVGEETPAAWQGLTLHARNAAELRVRLTSQDDETLSVEAVDSTG
LPVLTARSLALDAVPVNEPATSATDLLTLTWAGIATRQQQTGLTVGAFEDLAADGDAPVP
DVVVFTALPGNDDPLAQTRILTAQVLRTVQEWIGGERFSDSTLVVRTGTGLAAAAVSGLM
RSAQSEHPGRFILVESDDDALTPDQLAATVGLDEPRLRISDGRYEVPRLTRAHADEPEPE
RAWDPDGTVLITGGSGVLAGIVARHLVAERGVRHLLLLSRGTPDRALLSELAELGAAVDT
AACDVSDRAELARVLARVSPEHPLTAVIHTAGVVDDGVVESLSAQRLETVFRPKADGAWH
LHELTRDADLAAFVMYSSAAGVMAGAGQGNYAAANAFLDALAEERRAEGLPALAVAWGLW
EDASGLTAQLTDTDRDRIRRGGLRAISAEHGMRLFDNASRHSEPVLVAAPMEPVRDAEVP
ALLRSLHRPNVRRAALAGGAQWLAALAPEERAKALLKVVRDTAATVLGHADARTIPVTGA
FRDLGIDSLTAVELRNGLAKVTGLRLPATLVFDYPTPAVLAARLGELFTGENPVLVRTAS
VVGQDEPLAIVGMACRLPGGVSSPEDLWRLVESGTDAISGFPADRGWDAESLFDPDPDAV
GKSYCVEGGFLDSAASFDAGFFGISPREALAMDPQQRLIMEVSWEAFERAGIEPGSVRGS
DTGVFMGAYAGGYGAGADLGGFAATASATSVLSGRVSYFFGLEGPAITVDTACSSSLVAL
YQAGYALRQGECSLALVGGVTVMATPQSFVEFSRKSGLDSDGRCKAFADSADGTGWAEGV
GVLLVERLSDAQAKGHQVLAVVRSSAVNQDGASNGLSAPNGPSQQGVIRQALANAGLTTA
EVDVVEAHGTGTTLGDPIEAQAVIATYGQDRERPLLLGSLKSNIGHAQAASGVSGVIKMV
MALQHNTVPRTLHVDEPSRHVDWAAGAVELVRENQPWPGTDRPRRAGVSSFGVSGTNAHV
ILESAPPAQPAEEAQPVETPVVASDVLPLVISAKTQPALTEHEDRLRAYLAASPGVDTRA
VASTLAVTRSVFEHRAVLLGDDTVTGTAVSDPRVVFVFPGQGWQWLGMGSALRDSSIVFA
ERMAECAPALREFVDWDLFTVLDDPAVVDRVDVVQPASWRMMVSLAAVWQAAGVRPDAVI
GHSQGEIAAACVAGAVSMRDAARIVTLRSEAIARGLAGRGAMASVALPAQDVELVDGAWI
AAHNGPASTVIAGTPEAVDHVLTAHEARGVRVRRITVDYASHTPHVELIRDELLDITSDS
SSQAPVVPWLSTVDGSWVDSPLDVEYWYRNLREPVGFHPAVGQLQAEGDTVFVEVSASPV
LLQAMDDDVVTVATLRRDDGDATRMLTALAQAYVHGVTVDWPAILGTATTRVLDLPTYAF
QHQRYWLRSVDRAAADGHPLLGTVVDLPASDGVVLTGRVSLATHTWLADHAVRGSVLLPG
TAFVDLVVRAADEVESDVVDELVIETPLLLPQTGGVQLSVSVGGADESGHRAVMVFSQAD
NTDTWTRHVTATVSTSDSTVSLPEFASWPPAQARPVSVADFYDRLAAAGTEYGPAFQGLQ
AAWRDGDTVYAEVVLAEEQAQEAARFAVHPALLDAAMHASVLHTPDTDQQSVRMPFSWNH
VQIRATDTAMLRVAATPTTDGWSVRVADDTGRPVATIGSLVTRPVTADTLGSAADDLLTL
VWTEIPTPQQSSLSVGRYEDLADGDVPVPDVAVYTARPEADGSPDPLVQTRTLTAQVLQT
AQAWLGGERFTDSTLVVRTGTGLAAAAVSGLMRSAQSEHPGRFVLVESDDDSLTLHQLAA
TVGLDEPRLRVNDGRFEVPRLARVNAAEPESETVWDPHGTVLITGGSGVLAGALARHLVT
ERGVRHLLLLSRTTADEGLLNELGELGARVETADCDVSDRAGLARVLAGVSPEHPLTAVI
QTAGALDDGVLETLTAQRLDTVLRPKADGAWHLHELTRNTGLAAFVMYSSAAGVMGNPGQ
GNLAAATAFLDALADQRRAEGLPALALAWGSSEETSDLIGLRTISAERGMRLFDSASHRG
EPLLMAASLDPARAAEVPALLRSLRRPVARRAASADGGVQWLAALAPAEREKALLKVVCD
SAAVVLGHADARTIPVTGAFKDLGVDSLTAVELRNSLVKATGLRLPATMVFDYPTPTALA
ARLDELFTGENPAPVREPVPAVAQDEPLAIVGMACRLPGGVSSPEDLWRLVESGTDAVSG
FPTDRGWDVEGLFDPDPDAAGKSYRAEGGFLDTAAGFDAGFFGISPREALAMDPQQRLLL
EVSWEAFERAGIEPGSVRGSDTGVFIGAFPVGYGAGAAREGYGATAAPNVLSGRLSYFFG
LEGPAITMDTACSSSLVALHLAAQALRNGECSMALAGGVTVMATPEVFTEFARQRGLASD
GRCKAFADSADGAGFSEGAGLLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGFTAPNG
PAQQRVIRQALANAGLTTAEVDVVEAHGTGTTLGDPIEAQAVIATYGQDREQPLLLGTLK
SNVGHTQAAAGVSGVIKMVMALQHSTVPRTLHVNEPSRHVDWSAGAVELVTENQSWPVTG
RPRRAGVSAFGVSGTNAHVVLESAPPAQSVNNAQPVATPVVASELVPLVISAKTLPALTE
HEDRLRAYLAASPGADMRAVGSTLALTRSVFEHRAVLLGHDTVTVTGTGTAVSNPRVVFV
FPGQGWQWLGMGSALRGSSVVFAERMAECAAALSEFVDWDLFAVLDDPAVVDRVDVVQPA
SWAVMVSLAAVWQADGVRPDAVIGHSQGEIAAACVAGAVSLRDAARSVTLRSQAIARGLA
GRGAMASVALPAHEIELVDGAWIAAHNGPASTVVAGAPEAVDRVLAVHEARGVRVRRIAV
DYASHTPHVELIRDELLDITAGIGSQAPVVPWLSTVDGTWVEGPLDVEYWYRNLREPVGF
DSAVGQLRAEGDTVFVEVSASPVLLQAMDDDVVTVATLRRDDGDATRMLTALAQAFVEGV
TVDWPAILGTATTRVPDLPTYAFQHQRFWAEGADRSVAGGHPLLGVAVELPESDGVLLTG
RVSLATHAWLADHAVRGSVLLPGTGFVELVVRAADEVGCDVVDELVIETPLLLPSSASVH
LSVSVGEADESGRRGVTVFSRADGADAWTRHVSATIGVSGAALSLPELAAWPPAQAQPVG
LGDFYDRLTGAGYEYGPAFQGLQAAWRDGDTVFAEVALAEEQAEEAARFAVHPALLDAAL
DAGILNTLDNAEQGVRLPFSWNGVQVRATGSATLRVADNPTSDGWSVRVADDSGRPVATV
DSLVTRPVTADTLGSAADDLLTVVWTEIPTPQQTGLSVGRFEDLADGDVPVPEVVVCTAL
PDSSENPLAPLDPPDPLVQTRTLTTQVLQAVQAWLAGERFTDSTLVVRTGTGLATAGVSG
LMRSAQSEHPGRFVLVECDDNLTLQQLAATVGLDEPRLRVCDGRFEVPRLARANTPESSP
LTIPGDRAWLLEQSHSGTLRDLALVPAETAERPLQSGEVRVDVRAAGLNFRDVLIALGTY
PGEAVIGAEAAGVVLEVGPEVQDLAPGDRVFGLVGGGFGAVAIADRRMLGVIPDGWSFTT
AASVPVVFATAYYGLVDLAGLSAGESVLIHAAAGGVGMAATQIARHLGARIYATASTGKQ
HVLREAGLEDARIGDSRTTGFREMVLDTTDSRGVDVVLNSLSGDFVDASLDLLPRGGRFV
EMGKTDIRDPHQVTADRPGTSYQAFDLMDAGPDRLREIIADLLALFAQGVLLPLPVRAWD
IRQAREAFSWMSRARHIGKIVLTVPQQLDANGTVLVTGGSGVLAGIAARHLVAEQGVRHL
LLLSRSTPDDALINELGELGARVDTAICDVSDRAGLARILAGVSPEHPLTAVIHTAGALD
DGVVESLTAQQLETVLRPKADGAWHLHELTRDADLAAFVMYSSAAGVLGSGGQGNYAAAN
AFLDALAEQRRGEGLPALAVAWGLWEDASGLTAEMTDTDRDRIRRGGLRAISAGHGMGLL
DAASRHGEPVLLAAAMEPVREAEVPALLRLLHRPVARRAASTGGSSVQWLARLAPVEREK
ALLKLVCDGAATVLGHADASTIPATAAFKDLGIDSLTAVELRNSLTKATGLRLPATLVFD
YPTPTALAARLGEWFVGETPVPVRTSVSVVAQDEPLAIVGMACRLPGGVSSPEDLWRLLE
SGTDAVSGFPTDRGWDVENLFGPAAGDSYRLQGGFLDAAAGFDASFFGISPREALAMDPQ
QRLVLEVSWEAFERAGIEPGSVRGTDTGVFMGAYPGGYGIGADLGGFGATASAVSVLSGR
VSYFFGLEGPAITVDTACSSSLVALHQAGYALRQGECSLALVGGVTVMATPQTFVEFARQ
GGLAGDGRSKAFADSADGAGFSEGVGVLLVERLSDAQAKGHQVLAMLRSSAVNQDGASNG
LTAPNGPSQQRVIQAALSNAGLAAHEVDVVEAHGTGTTLGDPIEAQALLATYGQDREQPL
LLGSVKSNLGHTQAAAGVSGVIKMVMALQRGFVPRTLHVDEPSRHVDWSAGAVALVTENQ
PWPDMGRARRAGVSSFGISGTNAHVILESAPPTQPADNAVIERAPEWLPMVISARTQSAL
TEHEGRLRAYLAASPGVDMRAVASTLAITRSVFEHRAVLLGDDTVTGTAATDPRVVFVFP
GQGSQRAGMGEELAAAFPVFARIHQQVWDLLDVPDLEVNETGYAQPALFALQVALFGLLE
SWGVRPDAVVGHSVGELAAGYVSGLWSLEDACTLVSARARLMQALPAGGVMVAVPVSEDE
ARAVLGEGVEIAAVNGPSSVVLSGDEAAVLQAAEGLGKWTRLATSHAFHSARMEPMLEEF
RAVAEGLTYRTPQVSMAAGDQLTTTEYWVRQVRDTVRFGEQVASYEDAVFVELGADRSLA
RLVDGVAMLHGDHEAQAAVSALAHLYVNGVTVDWPALLGDAPATRVLDLPTYAFQHQRYW
LEGTDRMAAGGHPLLGEAVAVPGSDGVLLTGRVSLATHPWLADHAVRGSVLLPGTGFVEL
VVRAADEVGCDVIDELVIETPLLLPQTGGVQLSVAVAESDDSGRRAVTVFSRADNVDTWT
RHATVTVSNSDTTLSLPDLSAWPPAQAQPVNVADFYDQLTVVAYEYGPAFQGLQAAWRDG
DTVHAEVALAEEQAQDAARNAVHPALLDAALHAGILNTPDTEQGVRLPFSWNQVQVHAVG
SAMLRVAVTQAADGWSVRVADDTGRPVATIGSLVTRPVTADTLGSTTDDLLALTWTEIPA
PQETSLTIGRFEDLADADVPVPEVVVFTARPDSSENPLAQTRTLTAQVLQKIQAWLAEER
FTDSTLIVRIGTGLAAAAVSGLMRSGQSEHPGRFVLVESDDDTLAPDQLAATVELDEPRL
RISDGRFEVPRLTRTHAAEPESEKVWDPDGTVLITGGSGVLAGIAARHLVAERGVRHLLL
LSRSAPDGALISELGELGAQVATAVCDVSDRPGLVRVLADVSPEHPLTAVIHTAGVVDDG
VVESLTAQRLDTVLRPKADGAWHLHELTRDADLAAFVMYSSAAGVFGSAGQGNYAVANAF
LDALAEQRRAEGLPALALAWGLWEGTSGLTANLTDTDHDRIRRSGMRAISAEHGMRLFDG
ASRRRDPVLVAAAMEPVREAEVPAMLRSLHRPVARRAASGGAVRCLAALAPEERAKALVK
VVCDSAATVLGHADVDSIPVTAAFRDLGVDSLTAVELRNSLTKATGLRLPATLVFDYPTP
GALAARLEELFTGENPVQVRTPVSAVGQDEPLAIVGMACRLPGGVSSPEDLWRLVESGTD
AISGFPTDRGWDVENLFDSDPDAAGKSYCVEGGFLATAANFDASFFGISPREALAMDPQQ
RLVLEVSWEAFERAGIEPGSVRGSDTGVFMGAFPGGYGIGADLEGYGATAGLNVLSGRLS
YFFGLEGPAVTVDTACSSSLVALHQAGYALRQGECSLALIGGVTVMATPHTFVEFSRQRG
LASDGRCKAFADSADGTGWSEGVGVLLVERLSDAQAKGHQVLAVVRSSAVNQDGASNGLS
APNGPSQQRVIRQALANAGLTTAEVDVVEAHGTGTTLGDPIEAQAVIATYGQDRDQPVLL
GSVKSNVGHTQAAAGVSGVIKMVMALQHGLVPRTLHVDEPSRHVDWTDGAVELVTENQSW
PEAGRPRRAGVSSFGVSGTNAHVILESAPPTQAVDDVRPADAPVVASVMASELVPLVISA
KTQSALAEYEGRLRAYLAASPGVDMRAVASTLAMTRSVFEHRAVIVGDDTVSGTAATDPR
VVFVFPGQGSQRAGMGAELAAAFPVFARIHQQVWDLLDVPDLEVNETGYAQPALFALQVA
LFGLLESWGVRPDAVIGHSVGELAAAYVSGLWSLEDACTLVSARARLMQALPAGGVMVAV
PVSEDEARAVLGEGVEIAAVNGPSSVVLSGDEAAVLQAAEGLGKWTRLATSHAFHSARME
PMLEEFRAVAQGLTYHAPGVVMAAGDRVMTAEYWVRQVRDTVRFGEQVASYEDAVFVELG
ADRSLARLVDGVAMLHGDHETQAAIGALAHLYVNGVTVDWTALLGDVPVTRVLDLPTYAF
QQQRYWAEVGRSADVSGAGLDAVGHPLLGAVVALPGSDGVLLTGRVSLATHAWLADHAVR
GSVLLPGTGFVELVVRAADEVGCDVVDELIVEAPLLLPQTGGVQVSVSVGEADESGHRVV
TIFSRADNADTWVRHVSAVISTSDSTVSLSEFASWPPAQAQPVDVTGFYDPLMAEGYEYG
PAFQGLQAAWRYGDTVFAEVALAEEQVREAARYPSVHPALLDAALHACTLECADAEVGVG
LPFSWDGVRVHAGGSAMLRVAVTQAADGWSVRVADEIGRPVANVGSLVTRPVTADALGSA
ADDLLALTWAEIPAPEGTGLTVGRFEELVSDGDVPVPEVAVFTALPDNDDDPLEQTRKLT
GQVLQAVQEWLGGERFSDSTLVVRTGTGLAAAGVSGLMRSAQSEHPGRFVLVESDDDALA
LDQLAAAVGLDEPRLRISDGRFEAPRLTRTHAAEPESEKVWDPDGTVLITGGSGVLAGIA
VRHLVTERGVRHLLLLSRSAPDEALINQLGELGARVETAACDVSDRAALAQVLAGVSPEH
PLTAVIHTAGVLDDGVVESLTAQRLDAVLRPKADGAWNLHELTRDADLAAFVMYSSAAGV
LGSGGQGNYAAANAFLDALAEQRHAEGLPALAVAWGLWEDASGLTAQLTDTDRDRIRRGG
LRAISAEHGMGLFDSASRHSEPVLVAAPMEPVRDAEVPALLRSLHRPVARRAAAAGGARW
LAALAPAEREKALLKLVSDGAATVLGHADTSTIPATTAFKDLGIDSLTAVELRNSLAKAT
ELRLPATLVFDYPTPTALAARLDELFTGENPAPVRGPVSAVAQDEPLAIVGMACRLPGGV
SSPEDLWRLVESGTDAISGFPTDRGWDVENLYDPDPDAPGKSYSVQGGFLDAAAGFDASF
FGISPREALAMDPQQRLMLEVSWEAFERAGIEPGSVRGSDTGVFIGAYPGGYGIGADLGG
FGTTAGAASVLSGRVSYFFGLEGPAFTVDTACSSSLVALHQAGYALRQGECSLALVGGVT
VMPTPQTFVEFSRQRGLSADGRCKAFADAADGTGWAEGVGVLLVERLSDAQANGHQILAV
VRSSAVNQDGASNGLSAPNGPSQQRVIRAALSNAGLAPHEVDVVEAHGTGTTLGDPIEAQ
AVIATYGQGRGEPLLLGSLKSNVGHTQAAAGVSGVIKMVMALQHSMVPRTLHVDEPSRHV
DWSAGAVELVAENQPWPETGRPRRAGVSSFGISGTNAHVILESAPAQSVGDTAGSTPVLV
SELVPLVISAKTQPALTEHEDRLRAYLAASPGVDIRAVASTLAVTRSVFEHRAVLLGDET
VTGTAVSDPRIVFVFPGQGWQWLGMGSALRDSSVVFAERMAECAAALSEFVDWDLFAVLD
DPAVVDRVDVVQPASWAVMVSLAAVWQAAGVRPDAVIGHSQGEIAAACVAGAVSMRDAAR
IVTLRSQAIARGLAGRGAMASVALPAQDVELVDGAWIAAHNGPASTVIAGTPEAVDHVLT
ALRQRGAGAADHVDYASHTPHVELIRDELLDITSDSSSQDPLVPWLSTVDGTWVDSPLDG
EYWYRNLREPVGFHPAVSQLQAQGDTVFVEVSASPVLMQAMDDDVVTVATLRRDDGDATR
MLTALAQAYVHGVTVDWRAVLGDVPATRVLDLPTYAFQHQRYWAEAGRSADVSAAGLDAV
GHPLLGAVLAMPGSDGVMLTGRVSLATHAWLADHAVRGSVLLPGTGFVELVVRAADEVAC
DVVDELIVEAPLLLPQTGGVQLSVSVGEADESGHRAVTVFSRADSADAWVRHVSATVSVS
DTTVPTSDLTAWPPAQAKPVDVAGFYDQLTRAGYEYGPAFQGLQAAWRDGDTVFAEVALA
EEQTQDAARFAVHPAVLDAALHAGILNTPDADRDTVRLPFSWNHVQVHVTGSATLRVAMT
RVADGWGVRVADDIGRPVATIGSLVTRPVAADALGSAVDDLFALTWTEIPVSQQVGVTVG
KFEDLADGEVPMPDVVVFTALPDSGDPLAQTRRLTAEVLQAVQVWLAGERFTDSTLVVRT
GTGLAAAAVSGLMRSAQSEHPGRFVLVESDDDTLTPDQLAATVGLDEPRLRVIDGRYEAP
RLTRTGVAEPEPEGVWDPDGTVLITGGSGVLAGIAARHLVAERGVRHLLLLSRSAPDEAL
ISELAELGAAVVDTAVCDVSDRAGLARVLAGVSPDHPLTAVIHTAGVLDDGVVESLTARR
LDTVLRPKADGAWNLHELTRDIDLAAFVMYSSAAGVLGSAGQGNYAVANAFVDALAEQRR
AEGLPALALAWGLWEDASGLTAKLTGTDHDRIRRSGLRTITAERGMRLFDIASRQGEPVL
VATPMEPVREVEVPALLRLLHRPVARRAASTGDSSAQWLVGLAPEERAKALLKVVRDSAA
TVLGHADARSIPATGAFKDLGVDSLTAVELRNSLTKATGLRLPATMVFDYPTPADLAARL
GDLMNPRVQSTTLLAEIDRIEKMFTSVTFDDRQASAIKDRLSSVLNKWQRISSPEEVSTT
ALSSASASEILDFIDREFGDPTA