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Entry version 154 (11 Dec 2019)
Sequence version 1 (24 May 2005)
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Protein
Submitted name:

HLA class I antigen

Gene

HLA-A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
HLA class I antigenImported
Submitted name:
HLA class I histocompatibility antigenImported
Submitted name:
HLA class I histocompatibility antigen A alpha chainImported
Submitted name:
MHC class I antigenImported
Submitted name:
MHC class I proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HLA-AImported
Synonyms:HLAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei308 – 332HelicalSequence analysisAdd BLAST25

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501509775725 – 365Sequence analysisAdd BLAST341

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini209 – 295Ig-likeInterPro annotationAdd BLAST87

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni338 – 365DisorderedSequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi341 – 359PolarSequence analysisAdd BLAST19

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit
3.30.500.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
IPR010579 MHC_I_a_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PF06623 MHC_I_C, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01638 MHCCLASSI

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00407 IGc1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q53Z42-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVMAPRTLV LLLSGALALT QTWAGSHSMR YFFTSVSRPG RGEPRFIAVG
60 70 80 90 100
YVDDTQFVRF DSDAASQRME PRAPWIEQEG PEYWDGETRK VKAHSQTHRV
110 120 130 140 150
DLGTLRGYYN QSEAGSHTVQ RMYGCDVGSD WRFLRGYHQY AYDGKDYIAL
160 170 180 190 200
KEDLRSWTAA DMAAQTTKHK WEAAHVAEQL RAYLEGTCVE WLRRYLENGK
210 220 230 240 250
ETLQRTDAPK THMTHHAVSD HEATLRCWAL SFYPAEITLT WQRDGEDQTQ
260 270 280 290 300
DTELVETRPA GDGTFQKWAA VVVPSGQEQR YTCHVQHEGL PKPLTLRWEP
310 320 330 340 350
SSQPTIPIVG IIAGLVLFGA VITGAVVAAV MWRRKSSDRK GGSYSQAASS
360
DSAQGSDVSL TACKV
Length:365
Mass (Da):40,922
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB54A97B24B337C08
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY365426 mRNA Translation: AAQ64634.1
EU445471 Genomic DNA Translation: ACA34991.1
GQ996941 Genomic DNA Translation: ACX71601.1
KT819313 Genomic DNA Translation: AMO26199.1
KU639954 Genomic DNA Translation: AMP83988.1
KX373268 Genomic DNA Translation: ARB08596.1
KY391795 Genomic DNA Translation: ARO86292.1
KY126406 Genomic DNA Translation: ASA47525.1
KY126407 Genomic DNA Translation: ASA47526.1
KY126409 Genomic DNA Translation: ASA47528.1
KY126411 Genomic DNA Translation: ASA47530.1
KY235388 Genomic DNA Translation: ASA47536.1
KY350864 Genomic DNA Translation: ASA47547.1
KY350866 Genomic DNA Translation: ASA47549.1
KY350867 Genomic DNA Translation: ASA47550.1
KY350873 Genomic DNA Translation: ASA47556.1
KY368780 Genomic DNA Translation: ASA47561.1
KY368788 Genomic DNA Translation: ASA47569.1
MF382101 Genomic DNA Translation: AST08337.1
KY419428 Genomic DNA Translation: ASU50319.1
KY419429 Genomic DNA Translation: ASU50320.1
KY419430 Genomic DNA Translation: ASU50321.1
KY419431 Genomic DNA Translation: ASU50322.1
KY419432 Genomic DNA Translation: ASU50323.1
KY419433 Genomic DNA Translation: ASU50324.1
KY419434 Genomic DNA Translation: ASU50325.1
MF474216 Genomic DNA Translation: ASU61666.1
MF474217 Genomic DNA Translation: ASU61667.1
MF521513 Genomic DNA Translation: ASW16017.1
KY883672 Genomic DNA Translation: ATY50871.1
MG189573 Genomic DNA Translation: AUD08720.1
MG189574 Genomic DNA Translation: AUD08721.1
MG199205 Genomic DNA Translation: AUF72629.1
MG372831 Genomic DNA Translation: AUL81588.1
MG372832 Genomic DNA Translation: AUL81589.1
KY499650 Genomic DNA Translation: AUN50129.1
MG584002 Genomic DNA Translation: AUQ33062.1
MG603073 Genomic DNA Translation: AUQ33083.1
MG701431 Genomic DNA Translation: AUQ33111.1
MG701440 Genomic DNA Translation: AUQ33120.1
MG701441 Genomic DNA Translation: AUQ33121.1
MG701444 Genomic DNA Translation: AUQ33124.1
MG701470 Genomic DNA Translation: AUQ33143.1
MG724775 Genomic DNA Translation: AUQ33179.1
MG756771 Genomic DNA Translation: AUQ33238.1
MG571441 Genomic DNA Translation: AUV47233.1
MG779946 Genomic DNA Translation: AVE16195.1
MG779947 Genomic DNA Translation: AVE16196.1
MG873449 Genomic DNA Translation: AVK88301.1
MG930526 Genomic DNA Translation: AVV62561.1
MH049609 Genomic DNA Translation: AVV62589.1
MF069201 Genomic DNA Translation: AWB14527.1
MH173421 Genomic DNA Translation: AWM62180.1
MH173426 Genomic DNA Translation: AWM62185.1
MH173429 Genomic DNA Translation: AWM62188.1
MH173457 Genomic DNA Translation: AWM62215.1
MH215796 Genomic DNA Translation: AWM62290.1
MH294665 Genomic DNA Translation: AWM62321.1
MH347525 Genomic DNA Translation: AWM62324.1
MH347526 Genomic DNA Translation: AWM62325.1
MH347558 Genomic DNA Translation: AWM62356.1
MH069728 Genomic DNA Translation: AXM44145.1
MH401225 Genomic DNA Translation: AXN55385.1
MH477543 Genomic DNA Translation: AXN55401.1
MG905188 Genomic DNA Translation: AYE21452.1
MG905189 Genomic DNA Translation: AYE21453.1
MH758798 Genomic DNA Translation: AZL48302.1
MH758816 Genomic DNA Translation: AZL48318.1
MH802068 Genomic DNA Translation: AZL48339.1
MH824599 Genomic DNA Translation: AZL48345.1
MH924851 Genomic DNA Translation: AZL48364.1
MH924854 Genomic DNA Translation: AZL48367.1
MH973870 Genomic DNA Translation: AZL48404.1
MH973875 Genomic DNA Translation: AZL48409.1
MH973898 Genomic DNA Translation: AZL48432.1
MH973916 Genomic DNA Translation: AZL48449.1
MK005591 Genomic DNA Translation: AZL48458.1
MK032356 Genomic DNA Translation: AZL48489.1
AB774944 Genomic DNA Translation: BAN59790.1
AB774968 Genomic DNA Translation: BAN59814.1
LC257683 Genomic DNA Translation: BBD34001.1
LC326109 Genomic DNA Translation: BBD74345.1
LC326110 Genomic DNA Translation: BBD74346.1
AJ555412 Genomic DNA Translation: CAD87771.1
AJ575565 Genomic DNA Translation: CAE01416.1
AM286552 Genomic DNA Translation: CAL15397.1
AM943368 Genomic DNA Translation: CAQ15739.1
FN806797 Genomic DNA Translation: CBL59223.1
FN806800 Genomic DNA Translation: CBL59226.1
HG794376 Genomic DNA Translation: CDK41185.1
LN600104 Genomic DNA Translation: CEF48094.1
LN912949 Genomic DNA Translation: CUU97276.1
LN994624 Genomic DNA Translation: CUV66676.1
LN994688 Genomic DNA Translation: CUV66740.1
LN994693 Genomic DNA Translation: CUV66745.1
LN994729 Genomic DNA Translation: CUV66781.1
LN999550 Genomic DNA Translation: CUX90943.1
LN999551 Genomic DNA Translation: CUX90944.1
LN999561 Genomic DNA Translation: CUX90954.1
LN999599 Genomic DNA Translation: CUX90992.1
LN999610 Genomic DNA Translation: CUX91003.1
MH269333 Genomic DNA Translation: QAX33593.1
MH269334 Genomic DNA Translation: QAX33594.1
MH460453 Genomic DNA Translation: QBG49584.1
MH460454 Genomic DNA Translation: QBG49585.1
MK359164 Genomic DNA Translation: QCE30923.1
MH909755 Genomic DNA Translation: QCL09027.1
MH909767 Genomic DNA Translation: QCL09039.1
MK118157 Genomic DNA Translation: QCQ78439.1
MK058301 Genomic DNA Translation: QCR70251.1
MK814883 Genomic DNA Translation: QDC33438.1
MK814884 Genomic DNA Translation: QDC33439.1
MK279524 Genomic DNA Translation: QDC33589.1
LT575552 Genomic DNA Translation: SBL08386.1
LT575560 Genomic DNA Translation: SBL08442.1
LT575579 Genomic DNA Translation: SBL08594.1
LT575582 Genomic DNA Translation: SBL08619.1
LT575602 Genomic DNA Translation: SBL08784.1
LT575617 Genomic DNA Translation: SBL08898.1
LT596623 Genomic DNA Translation: SBV08727.1
LT599195 Genomic DNA Translation: SBW38416.1
LT607859 Genomic DNA Translation: SCL43779.1
LT618818 Genomic DNA Translation: SCQ83634.1
LT629255 Genomic DNA Translation: SDA09197.1
LT627699 Genomic DNA Translation: SFV42128.1
LT795513 Genomic DNA Translation: SJX71913.1
LT906366 Genomic DNA Translation: SNU78101.1
LT906374 Genomic DNA Translation: SNU78109.1
LT963181 Genomic DNA Translation: SOR74725.1
LT963184 Genomic DNA Translation: SOR74728.1
LT963189 Genomic DNA Translation: SOR74733.1
LT963196 Genomic DNA Translation: SOR74740.1
LT963202 Genomic DNA Translation: SOR74746.1
LT963227 Genomic DNA Translation: SOR74771.1
LT963238 Genomic DNA Translation: SOR74782.1
LT963246 Genomic DNA Translation: SOR74790.1
LT963251 Genomic DNA Translation: SOR74795.1
LT963254 Genomic DNA Translation: SOR74798.1
LT963260 Genomic DNA Translation: SOR74804.1
LT963274 Genomic DNA Translation: SOR74818.1
LT963275 Genomic DNA Translation: SOR74819.1
LT963276 Genomic DNA Translation: SOR74820.1
LT963279 Genomic DNA Translation: SOR74823.1
LT963297 Genomic DNA Translation: SOR74841.1
LS398186 Genomic DNA Translation: SPQ44315.1
LS398194 Genomic DNA Translation: SPQ44323.1

Genome annotation databases

UCSC genome browser

More...
UCSCi
uc011fur.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY365426 mRNA Translation: AAQ64634.1
EU445471 Genomic DNA Translation: ACA34991.1
GQ996941 Genomic DNA Translation: ACX71601.1
KT819313 Genomic DNA Translation: AMO26199.1
KU639954 Genomic DNA Translation: AMP83988.1
KX373268 Genomic DNA Translation: ARB08596.1
KY391795 Genomic DNA Translation: ARO86292.1
KY126406 Genomic DNA Translation: ASA47525.1
KY126407 Genomic DNA Translation: ASA47526.1
KY126409 Genomic DNA Translation: ASA47528.1
KY126411 Genomic DNA Translation: ASA47530.1
KY235388 Genomic DNA Translation: ASA47536.1
KY350864 Genomic DNA Translation: ASA47547.1
KY350866 Genomic DNA Translation: ASA47549.1
KY350867 Genomic DNA Translation: ASA47550.1
KY350873 Genomic DNA Translation: ASA47556.1
KY368780 Genomic DNA Translation: ASA47561.1
KY368788 Genomic DNA Translation: ASA47569.1
MF382101 Genomic DNA Translation: AST08337.1
KY419428 Genomic DNA Translation: ASU50319.1
KY419429 Genomic DNA Translation: ASU50320.1
KY419430 Genomic DNA Translation: ASU50321.1
KY419431 Genomic DNA Translation: ASU50322.1
KY419432 Genomic DNA Translation: ASU50323.1
KY419433 Genomic DNA Translation: ASU50324.1
KY419434 Genomic DNA Translation: ASU50325.1
MF474216 Genomic DNA Translation: ASU61666.1
MF474217 Genomic DNA Translation: ASU61667.1
MF521513 Genomic DNA Translation: ASW16017.1
KY883672 Genomic DNA Translation: ATY50871.1
MG189573 Genomic DNA Translation: AUD08720.1
MG189574 Genomic DNA Translation: AUD08721.1
MG199205 Genomic DNA Translation: AUF72629.1
MG372831 Genomic DNA Translation: AUL81588.1
MG372832 Genomic DNA Translation: AUL81589.1
KY499650 Genomic DNA Translation: AUN50129.1
MG584002 Genomic DNA Translation: AUQ33062.1
MG603073 Genomic DNA Translation: AUQ33083.1
MG701431 Genomic DNA Translation: AUQ33111.1
MG701440 Genomic DNA Translation: AUQ33120.1
MG701441 Genomic DNA Translation: AUQ33121.1
MG701444 Genomic DNA Translation: AUQ33124.1
MG701470 Genomic DNA Translation: AUQ33143.1
MG724775 Genomic DNA Translation: AUQ33179.1
MG756771 Genomic DNA Translation: AUQ33238.1
MG571441 Genomic DNA Translation: AUV47233.1
MG779946 Genomic DNA Translation: AVE16195.1
MG779947 Genomic DNA Translation: AVE16196.1
MG873449 Genomic DNA Translation: AVK88301.1
MG930526 Genomic DNA Translation: AVV62561.1
MH049609 Genomic DNA Translation: AVV62589.1
MF069201 Genomic DNA Translation: AWB14527.1
MH173421 Genomic DNA Translation: AWM62180.1
MH173426 Genomic DNA Translation: AWM62185.1
MH173429 Genomic DNA Translation: AWM62188.1
MH173457 Genomic DNA Translation: AWM62215.1
MH215796 Genomic DNA Translation: AWM62290.1
MH294665 Genomic DNA Translation: AWM62321.1
MH347525 Genomic DNA Translation: AWM62324.1
MH347526 Genomic DNA Translation: AWM62325.1
MH347558 Genomic DNA Translation: AWM62356.1
MH069728 Genomic DNA Translation: AXM44145.1
MH401225 Genomic DNA Translation: AXN55385.1
MH477543 Genomic DNA Translation: AXN55401.1
MG905188 Genomic DNA Translation: AYE21452.1
MG905189 Genomic DNA Translation: AYE21453.1
MH758798 Genomic DNA Translation: AZL48302.1
MH758816 Genomic DNA Translation: AZL48318.1
MH802068 Genomic DNA Translation: AZL48339.1
MH824599 Genomic DNA Translation: AZL48345.1
MH924851 Genomic DNA Translation: AZL48364.1
MH924854 Genomic DNA Translation: AZL48367.1
MH973870 Genomic DNA Translation: AZL48404.1
MH973875 Genomic DNA Translation: AZL48409.1
MH973898 Genomic DNA Translation: AZL48432.1
MH973916 Genomic DNA Translation: AZL48449.1
MK005591 Genomic DNA Translation: AZL48458.1
MK032356 Genomic DNA Translation: AZL48489.1
AB774944 Genomic DNA Translation: BAN59790.1
AB774968 Genomic DNA Translation: BAN59814.1
LC257683 Genomic DNA Translation: BBD34001.1
LC326109 Genomic DNA Translation: BBD74345.1
LC326110 Genomic DNA Translation: BBD74346.1
AJ555412 Genomic DNA Translation: CAD87771.1
AJ575565 Genomic DNA Translation: CAE01416.1
AM286552 Genomic DNA Translation: CAL15397.1
AM943368 Genomic DNA Translation: CAQ15739.1
FN806797 Genomic DNA Translation: CBL59223.1
FN806800 Genomic DNA Translation: CBL59226.1
HG794376 Genomic DNA Translation: CDK41185.1
LN600104 Genomic DNA Translation: CEF48094.1
LN912949 Genomic DNA Translation: CUU97276.1
LN994624 Genomic DNA Translation: CUV66676.1
LN994688 Genomic DNA Translation: CUV66740.1
LN994693 Genomic DNA Translation: CUV66745.1
LN994729 Genomic DNA Translation: CUV66781.1
LN999550 Genomic DNA Translation: CUX90943.1
LN999551 Genomic DNA Translation: CUX90944.1
LN999561 Genomic DNA Translation: CUX90954.1
LN999599 Genomic DNA Translation: CUX90992.1
LN999610 Genomic DNA Translation: CUX91003.1
MH269333 Genomic DNA Translation: QAX33593.1
MH269334 Genomic DNA Translation: QAX33594.1
MH460453 Genomic DNA Translation: QBG49584.1
MH460454 Genomic DNA Translation: QBG49585.1
MK359164 Genomic DNA Translation: QCE30923.1
MH909755 Genomic DNA Translation: QCL09027.1
MH909767 Genomic DNA Translation: QCL09039.1
MK118157 Genomic DNA Translation: QCQ78439.1
MK058301 Genomic DNA Translation: QCR70251.1
MK814883 Genomic DNA Translation: QDC33438.1
MK814884 Genomic DNA Translation: QDC33439.1
MK279524 Genomic DNA Translation: QDC33589.1
LT575552 Genomic DNA Translation: SBL08386.1
LT575560 Genomic DNA Translation: SBL08442.1
LT575579 Genomic DNA Translation: SBL08594.1
LT575582 Genomic DNA Translation: SBL08619.1
LT575602 Genomic DNA Translation: SBL08784.1
LT575617 Genomic DNA Translation: SBL08898.1
LT596623 Genomic DNA Translation: SBV08727.1
LT599195 Genomic DNA Translation: SBW38416.1
LT607859 Genomic DNA Translation: SCL43779.1
LT618818 Genomic DNA Translation: SCQ83634.1
LT629255 Genomic DNA Translation: SDA09197.1
LT627699 Genomic DNA Translation: SFV42128.1
LT795513 Genomic DNA Translation: SJX71913.1
LT906366 Genomic DNA Translation: SNU78101.1
LT906374 Genomic DNA Translation: SNU78109.1
LT963181 Genomic DNA Translation: SOR74725.1
LT963184 Genomic DNA Translation: SOR74728.1
LT963189 Genomic DNA Translation: SOR74733.1
LT963196 Genomic DNA Translation: SOR74740.1
LT963202 Genomic DNA Translation: SOR74746.1
LT963227 Genomic DNA Translation: SOR74771.1
LT963238 Genomic DNA Translation: SOR74782.1
LT963246 Genomic DNA Translation: SOR74790.1
LT963251 Genomic DNA Translation: SOR74795.1
LT963254 Genomic DNA Translation: SOR74798.1
LT963260 Genomic DNA Translation: SOR74804.1
LT963274 Genomic DNA Translation: SOR74818.1
LT963275 Genomic DNA Translation: SOR74819.1
LT963276 Genomic DNA Translation: SOR74820.1
LT963279 Genomic DNA Translation: SOR74823.1
LT963297 Genomic DNA Translation: SOR74841.1
LS398186 Genomic DNA Translation: SPQ44315.1
LS398194 Genomic DNA Translation: SPQ44323.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

UCSCiuc011fur.2 human

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
HLA-A human

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
IPR010579 MHC_I_a_C
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PF06623 MHC_I_C, 1 hit
PRINTSiPR01638 MHCCLASSI
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ53Z42_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q53Z42
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: December 11, 2019
This is version 154 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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