Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 101 (25 May 2022)
Sequence version 1 (24 May 2005)
Previous versions | rss
Add a publicationFeedback
Protein

Glutamate receptor

Gene

At1g05200

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Glutamate-gated receptor that probably acts as non-selective cation channel.

UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel, Ligand-gated ion channelUniRule annotationARBA annotation, ReceptorUniRule annotationARBA annotation
Biological processIon transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glutamate receptorUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At1g05200Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei616 – 634HelicalSequence analysisAdd BLAST19
Transmembranei646 – 664HelicalSequence analysisAdd BLAST19
Transmembranei676 – 702HelicalSequence analysisAdd BLAST27
Transmembranei858 – 882HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi786 ↔ 841UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation, GlycoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q53YX3, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q53YX3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini495 – 837PBPeInterPro annotationAdd BLAST343

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni893 – 913DisorderedSequence analysisAdd BLAST21
Regioni936 – 959DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi939 – 959Polar residuesSequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. [View classification]UniRule annotationARBA annotation

Keywords - Domaini

SignalARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007358_0_1_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
EREQVFV

Database of Orthologous Groups

More...
OrthoDBi
188544at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q53YX3

Family and domain databases

Conserved Domains Database

More...
CDDi
cd19990, PBP1_GABAb_receptor_plant, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001828, ANF_lig-bd_rcpt
IPR044440, GABAb_receptor_plant_PBP1
IPR001320, Iontro_rcpt
IPR017103, Iontropic_Glu_rcpt_pln
IPR028082, Peripla_BP_I
IPR001638, Solute-binding_3/MltF_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01094, ANF_receptor, 1 hit
PF00060, Lig_chan, 1 hit
PF00497, SBP_bac_3, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037090, Iontro_Glu-like_rcpt_pln, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00079, PBPe, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53822, SSF53822, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q53YX3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGFLVMIREV SMAKAIRVVL LCVSVLWVVP KECACRSNFS RNSSSSSSSS
60 70 80 90 100
LRPLRQRPSS VNVGALFTYD SFIGRAAKPA VKAAMDDVNA DQSVLKGIKL
110 120 130 140 150
NIIFQDSNCS GFIGTMGALQ LMENKVVAAI GPQSSGIAHM ISYVANELHV
160 170 180 190 200
PLLSFGATDP TLSSLQFPYF LRTTQNDYFQ MHAIADFLSY SGWRQVIAIF
210 220 230 240 250
VDDECGRNGI SVLGDVLAKK RSRISYKAAI TPGADSSSIR DLLVSVNLME
260 270 280 290 300
SRVFVVHVNP DSGLNVFSVA KSLGMMASGY VWIATDWLPT AMDSMEHVDS
310 320 330 340 350
DTMDLLQGVV AFRHYTIESS VKRQFMARWK NLRPNDGFNS YAMYAYDSVW
360 370 380 390 400
LVARALDVFF RENNNITFSN DPNLHKTNGS TIQLSALSVF NEGEKFMKII
410 420 430 440 450
LGMNHTGVTG PIQFDSDRNR VNPAYEVLNL EGTAPRTVGY WSNHSGLSVV
460 470 480 490 500
HPETLYSRPP NTSTANQRLK GIIYPGEVTK PPRGWVFPNN GKPLRIGVPN
510 520 530 540 550
RVSYTDYVSK DKNPPGVRGY CIDVFEAAIE LLPYPVPRTY ILYGDGKRNP
560 570 580 590 600
SYDNLVNEVV ADNFDVAVGD ITIVTNRTRY VDFTQPFIES GLVVVAPVKE
610 620 630 640 650
AKSSPWSFLK PFTIEMWAVT GGFFLFVGAM VWILEHRFNQ EFRGPPRRQL
660 670 680 690 700
ITIFWFSFST MFFSHRENTV SSLGRFVLII WLFVVLIINS SYTASLTSIL
710 720 730 740 750
TIRQLTSRIE GIDSLVTSNE PIGVQDGTFA RNYLINELNI LPSRIVPLKD
760 770 780 790 800
EEQYLSALQR GPNAGGVAAI VDELPYIEVL LTNSNCKFRT VGQEFTRTGW
810 820 830 840 850
GFAFQRDSPL AVDMSTAILQ LSEEGELEKI HRKWLNYKHE CSMQISNSED
860 870 880 890 900
SQLSLKSFWG LFLICGITCF MALTVFFWRV FWQYQRLLPE SADEERAGEV
910 920 930 940 950
SEPSRSGRGS RAPSFKELIK VVDKREAEIK EILKQKSSKK LKSTQSAAGT

SQSQHGEIT
Length:959
Mass (Da):107,207
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0709B834A76FAFC0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY438620 mRNA Translation: AAR13022.1

NCBI Reference Sequences

More...
RefSeqi
NP_001030971.1, NM_001035894.1
NP_001320831.1, NM_001331526.1
NP_172012.2, NM_100398.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G05200.1; AT1G05200.1; AT1G05200
AT1G05200.2; AT1G05200.2; AT1G05200
AT1G05200.6; AT1G05200.6; AT1G05200

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
839268

Gramene; a comparative resource for plants

More...
Gramenei
AT1G05200.1; AT1G05200.1; AT1G05200
AT1G05200.2; AT1G05200.2; AT1G05200
AT1G05200.6; AT1G05200.6; AT1G05200

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G05200

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY438620 mRNA Translation: AAR13022.1
RefSeqiNP_001030971.1, NM_001035894.1
NP_001320831.1, NM_001331526.1
NP_172012.2, NM_100398.3

3D structure databases

SMRiQ53YX3
ModBaseiSearch...

Genome annotation databases

EnsemblPlantsiAT1G05200.1; AT1G05200.1; AT1G05200
AT1G05200.2; AT1G05200.2; AT1G05200
AT1G05200.6; AT1G05200.6; AT1G05200
GeneIDi839268
GrameneiAT1G05200.1; AT1G05200.1; AT1G05200
AT1G05200.2; AT1G05200.2; AT1G05200
AT1G05200.6; AT1G05200.6; AT1G05200
KEGGiath:AT1G05200

Phylogenomic databases

HOGENOMiCLU_007358_0_1_1
OMAiEREQVFV
OrthoDBi188544at2759
PhylomeDBiQ53YX3

Gene expression databases

ExpressionAtlasiQ53YX3, baseline and differential

Family and domain databases

CDDicd19990, PBP1_GABAb_receptor_plant, 1 hit
InterProiView protein in InterPro
IPR001828, ANF_lig-bd_rcpt
IPR044440, GABAb_receptor_plant_PBP1
IPR001320, Iontro_rcpt
IPR017103, Iontropic_Glu_rcpt_pln
IPR028082, Peripla_BP_I
IPR001638, Solute-binding_3/MltF_N
PfamiView protein in Pfam
PF01094, ANF_receptor, 1 hit
PF00060, Lig_chan, 1 hit
PF00497, SBP_bac_3, 1 hit
PIRSFiPIRSF037090, Iontro_Glu-like_rcpt_pln, 1 hit
SMARTiView protein in SMART
SM00079, PBPe, 1 hit
SUPFAMiSSF53822, SSF53822, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ53YX3_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q53YX3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 25, 2022
This is version 101 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again