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Entry version 112 (08 May 2019)
Sequence version 1 (24 May 2005)
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Protein

C2 calcium-dependent domain-containing protein 6

Gene

C2CD6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
C2 calcium-dependent domain-containing protein 6
Alternative name(s):
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C2CD6Imported
Synonyms:ALS2CR11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14438 C2CD6

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q53TS8

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
151254

Open Targets

More...
OpenTargetsi
ENSG00000155754

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA24734

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C2CD6

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74726955

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000761741 – 623C2 calcium-dependent domain-containing protein 6Add BLAST623

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q53TS8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q53TS8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q53TS8

PeptideAtlas

More...
PeptideAtlasi
Q53TS8

PRoteomics IDEntifications database

More...
PRIDEi
Q53TS8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
62551
62552 [Q53TS8-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q53TS8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q53TS8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000155754 Expressed in 99 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q53TS8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q53TS8 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127358, 18 interactors

Protein interaction database and analysis system

More...
IntActi
Q53TS8, 59 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000409937

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q53TS8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini66 – 226C2Sequence analysisAdd BLAST161

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIHD Eukaryota
ENOG4112989 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018209

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000033889

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q53TS8

Identification of Orthologs from Complete Genome Data

More...
OMAi
KNGFDPF

Database of Orthologous Groups

More...
OrthoDBi
179359at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q53TS8

TreeFam database of animal gene trees

More...
TreeFami
TF328407

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031462 C2CD6

The PANTHER Classification System

More...
PANTHERi
PTHR21665 PTHR21665, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15729 ALS2CR11, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q53TS8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEPPQETNRP FSTLDNRSGQ VQVLSATPLL QRNPYSSPDI MHIKGSEASS
60 70 80 90 100
VPYALNQGTT ALPKNKNQEG TGHRLLNMLR KTLKESDSEE LEITQETPNL
110 120 130 140 150
VPFGDVVGCL GIHIKNCRHF MPKISLQHYA NLFIRISINK AVKCTKMCSL
160 170 180 190 200
LSKNDEKNTV IKFDEVKYFS VQVPRRYDDK RNNILLELIQ YDNREKRAFL
210 220 230 240 250
LGSVQIHLYE VIQKGCFIEE VQVLHGNIFV CRLEVEFMFS YGNFGYGFSH
260 270 280 290 300
QLKPLQKITE PSMFMNLAPP PERTDPVTKV ITPQTVEYPA FLSPDLNVTV
310 320 330 340 350
GTPAVQSSNQ PSVVRLEKLQ QQPRERLEKM KKEYRNLNTW IDKANYLESI
360 370 380 390 400
LMPKLEHKDS EETNIDEASE NTKSNHPEEE LENIVGVDIP LVNEEAETTA
410 420 430 440 450
NELLDNDSEK GLTIPTLNQS DQDNSTADAS KNDESTPSPT EVHSLCTISN
460 470 480 490 500
QETIKAGRIP PLGERQSESM PDRKMKNVFF PLEVKLKDNY PSILKADSSL
510 520 530 540 550
SEVAFSPKEY NSPSFRPEYI EFKPKFQDCS DKFEDLHDMT SFTHLKKVKS
560 570 580 590 600
RSRLLGKSSD DIHNHARHSA RPYTAPEVNK QRESYSGKFT SRRMVSSGLV
610 620
HINDKTSDYE MHKMRPKKIK RGY
Length:623
Mass (Da):71,159
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE716E5F34CC3868F
GO
Isoform 2 (identifier: Q53TS8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     388-395: DIPLVNEE → GGFFTKRI
     396-623: Missing.

Note: No experimental confirmation available.
Show »
Length:395
Mass (Da):45,227
Checksum:iA9E422C2006325DB
GO
Isoform 3 (identifier: Q53TS8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     504-550: AFSPKEYNSP...SFTHLKKVKS → NLRSICINPK...LVSTRLKIKR
     551-623: Missing.

Note: No experimental confirmation available.
Show »
Length:550
Mass (Da):62,411
Checksum:i7067FA0AC430A943
GO
Isoform 4 (identifier: Q53TS8-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     527-527: Q → QFQKFNKNGF...LHWTARRTIH

Note: No experimental confirmation available.Curated
Show »
Length:1,820
Mass (Da):209,056
Checksum:iD564B528D1600F3D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 4 (identifier: Q53TS8-4)
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti698M → T in BX648732 (PubMed:17974005).Curated1
Sequence conflicti1039C → G in BX648732 (PubMed:17974005).Curated1
Sequence conflicti1559M → I in BX648732 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_035787123K → M in a colorectal cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_024769376H → Q3 PublicationsCorresponds to variant dbSNP:rs10804117Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016788388 – 395DIPLVNEE → GGFFTKRI in isoform 2. 1 Publication8
Alternative sequenceiVSP_016789396 – 623Missing in isoform 2. 1 PublicationAdd BLAST228
Alternative sequenceiVSP_045400504 – 550AFSPK…KKVKS → NLRSICINPKSRNLDSSPTE ISWQNNNLNLAERENTGLVS TRLKIKR in isoform 3. 1 PublicationAdd BLAST47
Alternative sequenceiVSP_045401527Q → QFQKFNKNGFDPFLRNINKM SVRKRKDQDIYKYRNILGAE VIEHEDQDPPYPAQSKTAGP ANTTWAHDPNIFTTKMLETE NKLAPDPTINTIKGLDTKNS LKENLPNVSLPSIKGESSRA GNVQANTCHLSKSLNFTPHI EYLKQSMILKSILSENLQDL SDKLFSKPEVSMNSEAREKS SSPLLSIHDKSSSSMEDNVL EKKQDLNNWLSEKDILNSKT TLSQIIKNIPADSFSEGSQI IENIPADSLLEGGQVIKNIP EYSLSEGGQIIKNIPADSFL ESGPGQSPEVEEHVSKKHFE ADERDFPIKKNSSTKKKHLI SEVPNSKSGSSGTVHDYIMR QIFTAPIFSELEIEVKEPSE TPMNLENQLPTPWKRSLSSH ILFHEENADEIELPQPRSAT SQIIQAFPIDTLLESGIIKV IELDKEHHKSSLLGTGITSP KGNLKDSQEYYSEIRSETEP LSEQSIPIIPKDTTSVSRAE FIQEDQNMFPQDSSYYSIAN KELYLPRNGQRLCKDKNDLS STLESLTNSLMDKLSESDEI MLKSFLKNIFNVFFKYNHSE RRGQPEKELERLIQPSFTSD TEHLEELQEDFDKADKLDRK PILSPKLRVFLEELSESEVK HLKSELSKQIQHYLVERLSE SGHITKEDLPKIYQNLYLMN EKAEQKGPNSFQGKYSETVK EIMSFVNNFNHHFIDKHLEI KLRSFLKEILQNYFLKNISE SSLFNETASETIYPNISSLR TKSVSISFHELEQDISKGSF GRRFEINMKYPLSKSLQNYL IALSENELLHLKADLSKHLQ SLFIEKLSKSGLMTKKQLEG INQHINLLNSSSIPLKYIKT HLPFRDDCHFVEKHSEKQNK YSRIVQQTTLQTVSEDKLRE AELIREKEKKYFPLQNLKGN SSLIKEQKSYYTKEEAKTPS LIKVQPSSNENIQASPLSKS SEILTDILLKKLRKEHVFTQ LPQAENSVHKTEIQDPYSWG GKSKITQSKAWCEKTLKMKS LDRKEHVNIYKWTVQEKPEA VLTSYPRIPNARMPREDEYL NRITFPSWQSSTLTHFNTET GEKSKLEDQYCQTLKGNNNN NKKHLVTFAQYKKEIQTLYI KPDEICSEKCAKFPEIQSFQ YKVVEDEKNLKPHLFPELFK IEDLKPKVRKERDRVAQPKK SFNKIVRILPTTLPTTRIHL KKSVPRTLLHWTARRTIH in isoform 4. 1 Publication1
Alternative sequenceiVSP_045402551 – 623Missing in isoform 3. 1 PublicationAdd BLAST73

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK058080 mRNA Translation: BAB71654.1
AL833429 mRNA No translation available.
BX648732 mRNA No translation available.
AC007282 Genomic DNA Translation: AAY14693.1
BC030659 mRNA Translation: AAH30659.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2349.1 [Q53TS8-1]
CCDS54428.1 [Q53TS8-2]
CCDS54429.1 [Q53TS8-3]
CCDS54430.1 [Q53TS8-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001161688.1, NM_001168216.1 [Q53TS8-2]
NP_001161689.1, NM_001168217.1 [Q53TS8-3]
NP_001161693.1, NM_001168221.1 [Q53TS8-4]
NP_689738.3, NM_152525.5 [Q53TS8-1]
XP_011509038.1, XM_011510736.2 [Q53TS8-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000286195; ENSP00000286195; ENSG00000155754 [Q53TS8-1]
ENST00000439140; ENSP00000409937; ENSG00000155754 [Q53TS8-4]
ENST00000439802; ENSP00000400672; ENSG00000155754 [Q53TS8-2]
ENST00000450242; ENSP00000399016; ENSG00000155754 [Q53TS8-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
151254

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:151254

UCSC genome browser

More...
UCSCi
uc002uye.4 human [Q53TS8-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK058080 mRNA Translation: BAB71654.1
AL833429 mRNA No translation available.
BX648732 mRNA No translation available.
AC007282 Genomic DNA Translation: AAY14693.1
BC030659 mRNA Translation: AAH30659.1
CCDSiCCDS2349.1 [Q53TS8-1]
CCDS54428.1 [Q53TS8-2]
CCDS54429.1 [Q53TS8-3]
CCDS54430.1 [Q53TS8-4]
RefSeqiNP_001161688.1, NM_001168216.1 [Q53TS8-2]
NP_001161689.1, NM_001168217.1 [Q53TS8-3]
NP_001161693.1, NM_001168221.1 [Q53TS8-4]
NP_689738.3, NM_152525.5 [Q53TS8-1]
XP_011509038.1, XM_011510736.2 [Q53TS8-2]

3D structure databases

SMRiQ53TS8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127358, 18 interactors
IntActiQ53TS8, 59 interactors
STRINGi9606.ENSP00000409937

PTM databases

iPTMnetiQ53TS8
PhosphoSitePlusiQ53TS8

Polymorphism and mutation databases

BioMutaiC2CD6
DMDMi74726955

Proteomic databases

jPOSTiQ53TS8
MaxQBiQ53TS8
PaxDbiQ53TS8
PeptideAtlasiQ53TS8
PRIDEiQ53TS8
ProteomicsDBi62551
62552 [Q53TS8-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000286195; ENSP00000286195; ENSG00000155754 [Q53TS8-1]
ENST00000439140; ENSP00000409937; ENSG00000155754 [Q53TS8-4]
ENST00000439802; ENSP00000400672; ENSG00000155754 [Q53TS8-2]
ENST00000450242; ENSP00000399016; ENSG00000155754 [Q53TS8-3]
GeneIDi151254
KEGGihsa:151254
UCSCiuc002uye.4 human [Q53TS8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
151254
DisGeNETi151254

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C2CD6

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0002740
HGNCiHGNC:14438 C2CD6
neXtProtiNX_Q53TS8
OpenTargetsiENSG00000155754
PharmGKBiPA24734

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIHD Eukaryota
ENOG4112989 LUCA
GeneTreeiENSGT00390000018209
HOGENOMiHOG000033889
InParanoidiQ53TS8
OMAiKNGFDPF
OrthoDBi179359at2759
PhylomeDBiQ53TS8
TreeFamiTF328407

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ALS2CR11 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
151254

Protein Ontology

More...
PROi
PR:Q53TS8

Gene expression databases

BgeeiENSG00000155754 Expressed in 99 organ(s), highest expression level in testis
ExpressionAtlasiQ53TS8 baseline and differential
GenevisibleiQ53TS8 HS

Family and domain databases

InterProiView protein in InterPro
IPR031462 C2CD6
PANTHERiPTHR21665 PTHR21665, 2 hits
PfamiView protein in Pfam
PF15729 ALS2CR11, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC2CD6_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q53TS8
Secondary accession number(s): C9IZH7
, E9PGG4, Q8NCN6, Q96LN4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: May 24, 2005
Last modified: May 8, 2019
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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