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Entry version 104 (22 Apr 2020)
Sequence version 3 (31 Jul 2019)
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Protein

INO80 complex subunit D

Gene

INO80D

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5689603 UCH proteinases
R-HSA-5696394 DNA Damage Recognition in GG-NER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
INO80 complex subunit DCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:INO80DImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25997 INO80D

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q53TQ3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
54891

Open Targets

More...
OpenTargetsi
ENSG00000114933

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162392147

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q53TQ3 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
INO80D

Domain mapping of disease mutations (DMDM)

More...
DMDMi
189045499

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003195851 – 1027INO80 complex subunit DAdd BLAST1027

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki87Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei132PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q53TQ3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q53TQ3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q53TQ3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q53TQ3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q53TQ3

PeptideAtlas

More...
PeptideAtlasi
Q53TQ3

PRoteomics IDEntifications database

More...
PRIDEi
Q53TQ3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q53TQ3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q53TQ3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000114933 Expressed in blood and 213 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q53TQ3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q53TQ3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000114933 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the N-terminus of INO80.

3 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120238, 20 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-846 INO80 chromatin remodeling complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q53TQ3

Protein interaction database and analysis system

More...
IntActi
Q53TQ3, 17 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000384198

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q53TQ3 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi360 – 363Poly-Asp4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the INO80D family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEJY Eukaryota
ENOG410XP19 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157974

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_329723_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q53TQ3

KEGG Orthology (KO)

More...
KOi
K11668

Identification of Orthologs from Complete Genome Data

More...
OMAi
QMDAMAF

Database of Orthologous Groups

More...
OrthoDBi
172254at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q53TQ3

TreeFam database of animal gene trees

More...
TreeFami
TF324169

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025927 Potential_DNA-bd

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13891 zf-C3Hc3H, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q53TQ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYEGKHIHFS EVDNKPLCSY SPKLCKQRRL NGYAFCIRHV LEDKTAPFKQ
60 70 80 90 100
CEYVAKYNSQ RCTNPIPKSE DRRYCNSHLQ VLGFIPKKER KKKNDPIDEV
110 120 130 140 150
KVRHQMDTMA FSLTVPTLAL KMPNGLDGMS LSPPGARVPL HYLETELEDP
160 170 180 190 200
FAFNEEDDDL KKGATVRKKL QSKLAQNRQR QRETEILKVR QEHFSPPPAP
210 220 230 240 250
SQQQPPQQHS HLSPLSTSLK PPAPPQGSVC KSPQPQNTSL PMQGVAPTTH
260 270 280 290 300
TIAQARQLSH KRPLPLLPSS RAPTVDPPRT DRILMKATAF SPHFSCISRL
310 320 330 340 350
QRLVKLCTQK HQLDTDLFPH LGLDWSEESG EEPEDSEQAS PYQVAWSIRE
360 370 380 390 400
TLRYQRHASD DDDAESRSSR VTQLCTYFQQ KYKHLCRLER AESRQKKCRH
410 420 430 440 450
TFRKALLQAA SKEPECTGQL IQELRRAACS RTSISRTKLR EVEPAACSGT
460 470 480 490 500
VKGEQCANKA LPFTRHCFQH ILLNHSQQLF SSCTAKFADG QQCSVPVFDI
510 520 530 540 550
THQTPLCEEH AKKMDNFLRG DNSRKVQHQQ QRKPRKKTKP PALTKKHKKK
560 570 580 590 600
RRRGPRRPQK PIPPAVPQGN LSMPASVSLP VEASHIRSPS TPELSADELP
610 620 630 640 650
DDIANEITDI PHDLELNQED FSDVLPRLPD DLQDFDFFEG KNGDLLPTTE
660 670 680 690 700
EAEELERALQ AVTSLECLST IGVLAQSDGV PVQELSDRGI GVFSTGTGAS
710 720 730 740 750
GIQSLSREVN TDLGELLNGR IVHDNFSSLE LDENLLRSAT LSNPPTPLAG
760 770 780 790 800
QIQGQFSAPA NVGLTSATLI SQSALGERAF PGQFHGLHDG SHASQRPHPA
810 820 830 840 850
QLLSKADDLI TSRQQYSSDH SHSSPHGSHY DSEHVPSPYS DHITSPHTTS
860 870 880 890 900
YSGDNMAATF SAEMPIMAQH LLPTQLEVPL GGVVNPRTHW GNLPVNLGDP
910 920 930 940 950
SPFSNLLGAD GHLLSTSLST PPTTSNSETT QPAFATVTPS SSSVLPGLPQ
960 970 980 990 1000
TSFSGMGPSA ELMASTSPKQ QLPQFSAAFG HQLSSHSGIP KDLQPSHSSI
1010 1020
APPTGFTVTG ATATSTNNAS SPFPSPN
Length:1,027
Mass (Da):113,202
Last modified:July 31, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFC5E886AF361295D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JLZ4C9JLZ4_HUMAN
INO80 complex subunit D
INO80D
439Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JLV2C9JLV2_HUMAN
INO80 complex subunit D
INO80D
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH04193 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH11687 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH11687 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence AAH17290 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAX93069 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAA91079 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence BAA91079 differs from that shown. Reason: Frameshift.Curated
The sequence BAA91079 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence EAW70375 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti517F → S in BAA91079 (PubMed:14702039).Curated1
Sequence conflicti608T → A in BAG53330 (PubMed:14702039).Curated1
Sequence conflicti822 – 828HSSPHGS → AILPHPQ in BAA91079 (PubMed:14702039).Curated7
Sequence conflicti859 – 878TFSAE…TQLEV → PVCFRGYHRPASVAWGLLLN in BAG53330 (PubMed:14702039).CuratedAdd BLAST20

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_039012358A → V1 PublicationCorresponds to variant dbSNP:rs2909111Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC007383 Genomic DNA No translation available.
AC007679 Genomic DNA Translation: AAX93069.1 Sequence problems.
AC092677 Genomic DNA No translation available.
CH471063 Genomic DNA Translation: EAW70375.1 Sequence problems.
BC004193 mRNA Translation: AAH04193.2 Sequence problems.
BC011687 mRNA Translation: AAH11687.1 Sequence problems.
BC017290 mRNA Translation: AAH17290.2 Sequence problems.
BC136278 mRNA Translation: AAI36279.1
AK000316 mRNA Translation: BAA91079.1 Sequence problems.
AK096585 mRNA Translation: BAG53330.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46500.1

NCBI Reference Sequences

More...
RefSeqi
NP_060229.3, NM_017759.4
XP_011509672.1, XM_011511370.2
XP_011509673.1, XM_011511371.2
XP_011509675.1, XM_011511373.2
XP_011509677.1, XM_011511375.2
XP_011509678.1, XM_011511376.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000403263; ENSP00000384198; ENSG00000114933
ENST00000636453; ENSP00000490850; ENSG00000283510

Database of genes from NCBI RefSeq genomes

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GeneIDi
54891

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54891

UCSC genome browser

More...
UCSCi
uc002vaz.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007383 Genomic DNA No translation available.
AC007679 Genomic DNA Translation: AAX93069.1 Sequence problems.
AC092677 Genomic DNA No translation available.
CH471063 Genomic DNA Translation: EAW70375.1 Sequence problems.
BC004193 mRNA Translation: AAH04193.2 Sequence problems.
BC011687 mRNA Translation: AAH11687.1 Sequence problems.
BC017290 mRNA Translation: AAH17290.2 Sequence problems.
BC136278 mRNA Translation: AAI36279.1
AK000316 mRNA Translation: BAA91079.1 Sequence problems.
AK096585 mRNA Translation: BAG53330.1
CCDSiCCDS46500.1
RefSeqiNP_060229.3, NM_017759.4
XP_011509672.1, XM_011511370.2
XP_011509673.1, XM_011511371.2
XP_011509675.1, XM_011511373.2
XP_011509677.1, XM_011511375.2
XP_011509678.1, XM_011511376.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi120238, 20 interactors
ComplexPortaliCPX-846 INO80 chromatin remodeling complex
CORUMiQ53TQ3
IntActiQ53TQ3, 17 interactors
STRINGi9606.ENSP00000384198

PTM databases

iPTMnetiQ53TQ3
PhosphoSitePlusiQ53TQ3

Polymorphism and mutation databases

BioMutaiINO80D
DMDMi189045499

Proteomic databases

EPDiQ53TQ3
jPOSTiQ53TQ3
MassIVEiQ53TQ3
MaxQBiQ53TQ3
PaxDbiQ53TQ3
PeptideAtlasiQ53TQ3
PRIDEiQ53TQ3

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
51926 54 antibodies

Genome annotation databases

EnsembliENST00000403263; ENSP00000384198; ENSG00000114933
ENST00000636453; ENSP00000490850; ENSG00000283510
GeneIDi54891
KEGGihsa:54891
UCSCiuc002vaz.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54891
DisGeNETi54891

GeneCards: human genes, protein and diseases

More...
GeneCardsi
INO80D
HGNCiHGNC:25997 INO80D
HPAiENSG00000114933 Low tissue specificity
neXtProtiNX_Q53TQ3
OpenTargetsiENSG00000114933
PharmGKBiPA162392147

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IEJY Eukaryota
ENOG410XP19 LUCA
GeneTreeiENSGT00940000157974
HOGENOMiCLU_329723_0_0_1
InParanoidiQ53TQ3
KOiK11668
OMAiQMDAMAF
OrthoDBi172254at2759
PhylomeDBiQ53TQ3
TreeFamiTF324169

Enzyme and pathway databases

ReactomeiR-HSA-5689603 UCH proteinases
R-HSA-5696394 DNA Damage Recognition in GG-NER

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
INO80D human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
54891
PharosiQ53TQ3 Tdark

Protein Ontology

More...
PROi
PR:Q53TQ3
RNActiQ53TQ3 protein

Gene expression databases

BgeeiENSG00000114933 Expressed in blood and 213 other tissues
ExpressionAtlasiQ53TQ3 baseline and differential
GenevisibleiQ53TQ3 HS

Family and domain databases

InterProiView protein in InterPro
IPR025927 Potential_DNA-bd
PfamiView protein in Pfam
PF13891 zf-C3Hc3H, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIN80D_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q53TQ3
Secondary accession number(s): B3KU68
, B9EG77, Q6PJC6, Q6PJU1, Q6PKA1, Q9NXD5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 31, 2019
Last modified: April 22, 2020
This is version 104 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
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