UniProtKB - Q53SS8 (Q53SS8_HUMAN)
Protein
Submitted name:
Epididymis secretory protein Li 85
Gene
PCBP1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: Ensembl
- RNA binding Source: InterPro
- sequence-specific single stranded DNA binding Source: Ensembl
GO - Biological processi
- positive regulation of transcription by RNA polymerase II Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: Epididymis secretory protein Li 85ImportedSubmitted name: Poly(RC) binding protein 1ImportedSubmitted name: cDNA, FLJ94964, highly similar to Homo sapiens poly(rC) binding protein 1 (PCBP1), mRNAImported |
Gene namesi | Name:PCBP1Imported Synonyms:HEL-S-85Imported ORF Names:hCG_1776997Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000169564.6 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Nucleus
- nuclear speck Source: HPA
- nucleoplasm Source: HPA
Other locations
- cytoplasmic ribonucleoprotein granule Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000169564, Expressed in vastus lateralis and 248 other tissues |
ExpressionAtlasi | Q53SS8, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 12 – 80 | KHInterPro annotationAdd BLAST | 69 | |
Domaini | 96 – 167 | KHInterPro annotationAdd BLAST | 72 | |
Domaini | 278 – 348 | KHInterPro annotationAdd BLAST | 71 |
Phylogenomic databases
HOGENOMi | CLU_022670_0_1_1 |
OMAi | TLTKLHQ |
OrthoDBi | 954970at2759 |
Family and domain databases
Gene3Di | 3.30.1370.10, 3 hits |
InterProi | View protein in InterPro IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf |
Pfami | View protein in Pfam PF00013, KH_1, 3 hits |
SMARTi | View protein in SMART SM00322, KH, 3 hits |
SUPFAMi | SSF54791, SSF54791, 3 hits |
i Sequence
Sequence statusi: Complete.
Q53SS8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDAGVTESGL NVTLTIRLLM HGKEVGSIIG KKGESVKRIR EESGARINIS
60 70 80 90 100
EGNCPERIIT LTGPTNAIFK AFAMIIDKLE EDINSSMTNS TAASRPPVTL
110 120 130 140 150
RLVVPATQCG SLIGKGGCKI KEIRESTGAQ VQVAGDMLPN STERAITIAG
160 170 180 190 200
VPQSVTECVK QICLVMLETL SQSPQGRVMT IPYQPMPASS PVICAGGQDR
210 220 230 240 250
CSDAAGYPHA THDLEGPPLD AYSIQGQHTI SPLDLAKLNQ VARQQSHFAM
260 270 280 290 300
MHGGTGFAGI DSSSPEVKGY WASLDASTQT THELTIPNNL IGCIIGRQGA
310 320 330 340 350
NINEIRQMSG AQIKIANPVE GSSGRQVTIT GSAASISLAQ YLINARLSSE
KGMGCS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016700 Genomic DNA Translation: AAX93191.1 FJ224329 mRNA Translation: ACI46021.1 AK314225 mRNA Translation: BAG36897.1 CH471053 Genomic DNA Translation: EAW99834.1 |
RefSeqi | NP_006187.2, NM_006196.3 |
Genome annotation databases
GeneIDi | 5093 |
KEGGi | hsa:5093 |
UCSCi | uc002sgf.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016700 Genomic DNA Translation: AAX93191.1 FJ224329 mRNA Translation: ACI46021.1 AK314225 mRNA Translation: BAG36897.1 CH471053 Genomic DNA Translation: EAW99834.1 |
RefSeqi | NP_006187.2, NM_006196.3 |
3D structure databases
SMRi | Q53SS8 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q53SS8, 4 interactors |
Proteomic databases
MaxQBi | Q53SS8 |
PRIDEi | Q53SS8 |
Protocols and materials databases
Antibodypediai | 16295, 428 antibodies |
DNASUi | 5093 |
Genome annotation databases
GeneIDi | 5093 |
KEGGi | hsa:5093 |
UCSCi | uc002sgf.4, human |
Organism-specific databases
CTDi | 5093 |
PharmGKBi | PA32986 |
VEuPathDBi | HostDB:ENSG00000169564.6 |
Phylogenomic databases
HOGENOMi | CLU_022670_0_1_1 |
OMAi | TLTKLHQ |
OrthoDBi | 954970at2759 |
Miscellaneous databases
BioGRID-ORCSi | 5093, 766 hits in 1005 CRISPR screens |
ChiTaRSi | PCBP1, human |
GenomeRNAii | 5093 |
Gene expression databases
Bgeei | ENSG00000169564, Expressed in vastus lateralis and 248 other tissues |
ExpressionAtlasi | Q53SS8, baseline and differential |
Family and domain databases
Gene3Di | 3.30.1370.10, 3 hits |
InterProi | View protein in InterPro IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf |
Pfami | View protein in Pfam PF00013, KH_1, 3 hits |
SMARTi | View protein in SMART SM00322, KH, 3 hits |
SUPFAMi | SSF54791, SSF54791, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q53SS8_HUMAN | |
Accessioni | Q53SS8Primary (citable) accession number: Q53SS8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 24, 2005 |
Last sequence update: | May 24, 2005 | |
Last modified: | April 7, 2021 | |
This is version 131 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |