UniProtKB - Q53SE7 (Q53SE7_HUMAN)
Protein
Submitted name:
Germ cell-less homolog 1 (Drosophila)
Gene
FLJ13057
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- germ cell development Source: InterPro
- multicellular organism development Source: UniProtKB-KW
Keywordsi
Molecular function | Developmental proteinARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Germ cell-less homolog 1 (Drosophila)Imported |
Gene namesi | Name:FLJ13057Imported Synonyms:GMCL1Imported ORF Names:hCG_40576Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000087338.4 |
Expressioni
Gene expression databases
Bgeei | ENSG00000087338, Expressed in testis and 222 other tissues |
ExpressionAtlasi | Q53SE7, baseline and differential |
Interactioni
Binary interactionsi
Q53SE7
Protein-protein interaction databases
IntActi | Q53SE7, 58 interactors |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 108 – 178 | BTBInterPro annotationAdd BLAST | 71 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 35 | DisorderedSequence analysisAdd BLAST | 35 | |
Regioni | 65 – 85 | DisorderedSequence analysisAdd BLAST | 21 |
Phylogenomic databases
HOGENOMi | CLU_025961_2_0_1 |
OMAi | YACASIY |
OrthoDBi | 1111791at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR011705, BACK IPR000210, BTB/POZ_dom IPR043380, Gcl-like IPR011333, SKP1/BTB/POZ_sf |
PANTHERi | PTHR23231, PTHR23231, 1 hit |
Pfami | View protein in Pfam PF07707, BACK, 1 hit PF00651, BTB, 1 hit |
SMARTi | View protein in SMART SM00875, BACK, 1 hit SM00225, BTB, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit |
i Sequence
Sequence statusi: Complete.
Q53SE7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSLSSRVLR QPRPALAQQA QGARAGGSAR RPDTGDDAAG HGFCYCAGSH
60 70 80 90 100
KRKRSSGSFC YCHPDSETDE DEEEGDEQQR LLNTPRRKKL KSTSKYIYQT
110 120 130 140 150
LFLNGENSDI KICALGEEWS LHKIYLCQSG YFSSMFSGSW KESSMNIIEL
160 170 180 190 200
EIPDQNIDVE ALQVAFGSLY RDDVLIKPSR VVAILAAACL LQLDGLIQQC
210 220 230 240 250
GETMKETVNV KTVCGYYTSA GTYGLDSVKK KCLEWLLNNL MTHQNVELFK
260 270 280 290 300
ELSINVMKQL IGSSNLFVMQ VEMDIYTALK KWMFLQLVPS WNGSLKQLLT
310 320 330 340 350
ETDVWFSKQR KDFEGMAFLE TEQGKPFVSV FRHLRLQYII SDLASARIIE
360 370 380 390 400
QDAVVPSEWL SSVYKQQWFA MLRAEQDSEV GPQEINKEEL EGNSMRCGRK
410 420 430 440 450
LAKDGEYCWR WTGFNFGFDL LVTYTNRYII FKRNTLNQPC SGSVSLQPRR
460 470 480 490 500
SIAFRLRLAS FDSSGKLICS RTTGYQILTL EKDQEQVVMN LDSRLLIFPL
510
YICCNFLYIS PEKKN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC019206 Genomic DNA Translation: AAY14865.1 CH471053 Genomic DNA Translation: EAW99842.1 |
RefSeqi | NP_848526.1, NM_178439.4 |
Genome annotation databases
GeneIDi | 64395 |
KEGGi | hsa:64395 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC019206 Genomic DNA Translation: AAY14865.1 CH471053 Genomic DNA Translation: EAW99842.1 |
RefSeqi | NP_848526.1, NM_178439.4 |
3D structure databases
SMRi | Q53SE7 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q53SE7, 58 interactors |
Protocols and materials databases
Antibodypediai | 48205, 66 antibodies |
DNASUi | 64395 |
Genome annotation databases
GeneIDi | 64395 |
KEGGi | hsa:64395 |
Organism-specific databases
CTDi | 64395 |
PharmGKBi | PA143485477 |
VEuPathDBi | HostDB:ENSG00000087338.4 |
Phylogenomic databases
HOGENOMi | CLU_025961_2_0_1 |
OMAi | YACASIY |
OrthoDBi | 1111791at2759 |
Miscellaneous databases
BioGRID-ORCSi | 64395, 5 hits in 989 CRISPR screens |
ChiTaRSi | GMCL1, human |
GenomeRNAii | 64395 |
Gene expression databases
Bgeei | ENSG00000087338, Expressed in testis and 222 other tissues |
ExpressionAtlasi | Q53SE7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR011705, BACK IPR000210, BTB/POZ_dom IPR043380, Gcl-like IPR011333, SKP1/BTB/POZ_sf |
PANTHERi | PTHR23231, PTHR23231, 1 hit |
Pfami | View protein in Pfam PF07707, BACK, 1 hit PF00651, BTB, 1 hit |
SMARTi | View protein in SMART SM00875, BACK, 1 hit SM00225, BTB, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q53SE7_HUMAN | |
Accessioni | Q53SE7Primary (citable) accession number: Q53SE7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 24, 2005 |
Last sequence update: | May 24, 2005 | |
Last modified: | April 7, 2021 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |