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UniProtKB - Q53SE3 (Q53SE3_HUMAN)
Protein
Origin recognition complex subunit 4
Gene
ORC4
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
GO - Biological processi
- DNA replication Source: InterPro
Names & Taxonomyi
Protein namesi | Recommended name: Origin recognition complex subunit 4ARBA annotation |
Gene namesi | Name:ORC4 Synonyms:ORC4LImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:8490, ORC4 |
VEuPathDBi | HostDB:ENSG00000115947 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Nucleus
- nucleolus Source: HPA
- nucleoplasm Source: HPA
Other locations
- origin recognition complex Source: InterPro
Expressioni
Gene expression databases
Bgeei | ENSG00000115947, Expressed in kidney and 236 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 37 – 85 | AAA_16InterPro annotationAdd BLAST | 49 |
Phylogenomic databases
GeneTreei | ENSGT00390000016542 |
OMAi | KVSTTMQ |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR041664, AAA_16 IPR016527, ORC4 IPR027417, P-loop_NTPase |
PANTHERi | PTHR12087, PTHR12087, 1 hit |
Pfami | View protein in Pfam PF13191, AAA_16, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
Q53SE3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSRKSKSNS LIHTECLSQV QRILRERFCR QSPHSNLFGV QVQYKHLSEL
60 70 80 90 100
LKRTALHGES NSVLIIGPRG SGKTMLINHA LKELMEIEEV SENVLQVHLN
110 120 130 140
GLLQINDKIA LKEITRQLNL ENVVGDKVFG SFAENLSFLL EALKK
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO43929 | ORC4_HUMAN | Origin recognition complex subunit ... | ORC4 ORC4L | 436 | Annotation score: | ||
C9J2X8 | C9J2X8_HUMAN | Origin recognition complex subunit ... | ORC4 | 128 | Annotation score: | ||
C9JGH7 | C9JGH7_HUMAN | Origin recognition complex subunit ... | ORC4 | 127 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 145 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009480 Genomic DNA No translation available. AC019226 Genomic DNA Translation: AAY24232.1 |
Genome annotation databases
Ensembli | ENST00000416719.5; ENSP00000413939.1; ENSG00000115947.14 |
UCSCi | uc061omk.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009480 Genomic DNA No translation available. AC019226 Genomic DNA Translation: AAY24232.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
ProteomicsDBi | 62535 |
Protocols and materials databases
Antibodypediai | 4189, 248 antibodies from 33 providers |
Genome annotation databases
Ensembli | ENST00000416719.5; ENSP00000413939.1; ENSG00000115947.14 |
UCSCi | uc061omk.1, human |
Organism-specific databases
HGNCi | HGNC:8490, ORC4 |
OpenTargetsi | ENSG00000115947 |
VEuPathDBi | HostDB:ENSG00000115947 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000016542 |
OMAi | KVSTTMQ |
Miscellaneous databases
ChiTaRSi | ORC4, human |
Gene expression databases
Bgeei | ENSG00000115947, Expressed in kidney and 236 other tissues |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR041664, AAA_16 IPR016527, ORC4 IPR027417, P-loop_NTPase |
PANTHERi | PTHR12087, PTHR12087, 1 hit |
Pfami | View protein in Pfam PF13191, AAA_16, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q53SE3_HUMAN | |
Accessioni | Q53SE3Primary (citable) accession number: Q53SE3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 24, 2005 |
Last sequence update: | May 24, 2005 | |
Last modified: | May 25, 2022 | |
This is version 118 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |