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Protein

Ras-related protein Rab-6D

Gene

RAB6D

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi20 – 28GTPBy similarity9
Nucleotide bindingi38 – 45GTPBy similarity8
Nucleotide bindingi68 – 72GTPBy similarity5
Nucleotide bindingi126 – 129GTPBy similarity4
Nucleotide bindingi156 – 158GTPBy similarity3

GO - Molecular functioni

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein Rab-6DCurated
Alternative name(s):
Rab6-like protein WTH3DICurated
Gene namesi
Name:RAB6DImported
Synonyms:WTH3DIImported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:30272 RAB6D

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004438251 – 254Ras-related protein Rab-6DAdd BLAST254

Proteomic databases

EPDiQ53S08
MaxQBiQ53S08
PeptideAtlasiQ53S08
PRIDEiQ53S08

PTM databases

iPTMnetiQ53S08
PhosphoSitePlusiQ53S08

Structurei

3D structure databases

SMRiQ53S08
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0094 Eukaryota
ENOG410XPBI LUCA
GeneTreeiENSGT00910000144073
HOVERGENiHBG009351
KOiK07895
OMAiKEYGVMF

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51419 RAB, 1 hit

Sequencei

Sequence statusi: Complete.

Q53S08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAGGDFGNP LRKFKLVFLG EQSVAKTSLI TRFRYDSFDN TYQAIIGIDF
60 70 80 90 100
LSKTMYLEDG TIGLRLWDTA GQERLRSLIP RYIRDSAAAV VVYDITNVNS
110 120 130 140 150
FQQTTKWIDD VRTEGGSDVI ITLVGNKTDL ADKRQVSIEE GERKAKGLNV
160 170 180 190 200
TFIETRAKAG YNVKQLFRRV AAALPGMEST QDGSREDMSD IKLEKPQEQT
210 220 230 240 250
VSEGGCSCYS PMSSSTLPQK PPYSFIDCSV NIGLNLFPSL ITFCNSSLLP

VSWR
Length:254
Mass (Da):28,242
Last modified:May 24, 2005 - v1
Checksum:i0FA8F665DFDAA081
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB232598 mRNA Translation: BAF02860.1
AY970296 Genomic DNA Translation: AAY33873.1
AC073869 Genomic DNA Translation: AAX93251.1
CCDSiCCDS82514.1
RefSeqiNP_001071105.1, NM_001077637.1
UniGeneiHs.645670

Genome annotation databases

EnsembliENST00000623617; ENSP00000490038; ENSG00000233087
GeneIDi150786
KEGGihsa:150786

Similar proteinsi

Entry informationi

Entry nameiRAB6D_HUMAN
AccessioniPrimary (citable) accession number: Q53S08
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 25, 2018
Last sequence update: May 24, 2005
Last modified: July 18, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

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