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Protein
Submitted name:

Uncharacterized protein SCN9A

Gene

SCN9A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized protein SCN9AImported
Gene namesi
Name:SCN9AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei122 – 145HelicalSequence analysisAdd BLAST24
Transmembranei190 – 209HelicalSequence analysisAdd BLAST20
Transmembranei221 – 242HelicalSequence analysisAdd BLAST22
Transmembranei248 – 268HelicalSequence analysisAdd BLAST21
Transmembranei378 – 405HelicalSequence analysisAdd BLAST28
Transmembranei726 – 752HelicalSequence analysisAdd BLAST27
Transmembranei764 – 782HelicalSequence analysisAdd BLAST19
Transmembranei802 – 823HelicalSequence analysisAdd BLAST22
Transmembranei844 – 872HelicalSequence analysisAdd BLAST29
Transmembranei934 – 957HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ53QP0
PRIDEiQ53QP0

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini125 – 411Ion_transInterPro annotationAdd BLAST287
Domaini484 – 683Na_trans_cytoplInterPro annotationAdd BLAST200
Domaini734 – 962Ion_transInterPro annotationAdd BLAST229
Domaini971 – 1146Na_trans_assocInterPro annotationAdd BLAST176

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili276 – 296Sequence analysisAdd BLAST21
Coiled coili402 – 447Sequence analysisAdd BLAST46
Coiled coili675 – 695Sequence analysisAdd BLAST21
Coiled coili1009 – 1029Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG2301 Eukaryota
ENOG410XNP6 LUCA
HOVERGENiHBG053100

Family and domain databases

Gene3Di1.20.120.350, 2 hits
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR010526 Na_trans_assoc
IPR024583 Na_trans_cytopl
IPR028803 SCN9A
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR10037:SF221 PTHR10037:SF221, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 2 hits
PF06512 Na_trans_assoc, 1 hit
PF11933 Na_trans_cytopl, 1 hit

Sequencei

Sequence statusi: Fragment.

Q53QP0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAMLPPPGPQ SFVHFTKQSL ALIEQRIAER KSKEPKEEKK DDDEEAPKPS
60 70 80 90 100
SDLEAGKQLP FIYGDIPPGM VSEPLEDLDP YYADKKTFIV LNKGKTIFRF
110 120 130 140 150
NATPALYMLS PFSPLRRISI KILVHSLFSM LIMCTILTNC IFMTMNNPPD
160 170 180 190 200
WTKNVEYTFT GIYTFESLVK ILARGFCVGE FTFLRDPWNW LDFVVIVFAY
210 220 230 240 250
LTEFVNLGNV SALRTFRVLR ALKTISVIPG LKTIVGALIQ SVKKLSDVMI
260 270 280 290 300
LTVFCLSVFA LIGLQLFMGN LKHKCFRNSL ENNETLESIM NTLESEEDFR
310 320 330 340 350
KYFYYLEGSK DALLCGFSTD SGQCPEGYTC VKIGRNPDYG YTSFDTFSWA
360 370 380 390 400
FLALFRLMTQ DYWENLYQQT LRAAGKTYMI FFVVVIFLGS FYLINLILAV
410 420 430 440 450
VAMAYEEQNQ ANIEEAKQKE LEFQQMLDRL KKEQEEAEAI AAAAAEYTSI
460 470 480 490 500
RRSRIMGLSE SSSETSKLSS KSAKERRNRR KKKNQKKLSS GEEKGDAEKL
510 520 530 540 550
SKSESEDSIR RKSFHLGVEG HRRAHEKRLS TPNQSPLSIR GSLFSARRSS
560 570 580 590 600
RTSLFSFKGR GRDIGSETEF ADDEHSIFGD NESRRGSLFV PHRPQERRSS
610 620 630 640 650
NISQASRSPP MLPVNGKMHS AVDCNGVVSL VDGRSALMLP NGQLLPEGTT
660 670 680 690 700
NQIHKKRRCS SYLLSEDMLN DPNLRQRAMS RASILTNTVE ELEESRQKCP
710 720 730 740 750
PWWYRFAHKF LIWNCSPYWI KFKKCIYFIV MDPFVDLAIT ICIVLNTLFM
760 770 780 790 800
AMEHHPMTEE FKNVLAIGNL VFTGIFAAEM VLKLIAMDPY EYFQVGWNIF
810 820 830 840 850
DSLIVTLSLV ELFLADVEGL SVLRSFRLLR VFKLAKSWPT LNMLIKIIGN
860 870 880 890 900
SVGALGNLTL VLAIIVFIFA VVGMQLFGKS YKECVCKIND DCTLPRWHMN
910 920 930 940 950
DFFHSFLIVF RVLCGEWIET MWDCMEVAGQ AMCLIVYMMV MVIGNLVVLN
960 970 980 990 1000
LFLALLLSSF SSDNLTAIEE DPDANNLQIA VTRIKKGINY VKQTLREFIL
1010 1020 1030 1040 1050
KAFSKKPKIS REIRQAEDLN TKKENYISNH TLAEMSKGHN FLKEKDKISG
1060 1070 1080 1090 1100
FGSSVDKHLM EDSDGQSFIH NPSLTVTVPI APGESDLENM NAEELSSDSD
1110 1120 1130 1140
SEYSKVRLNR SSSSECSTVD NPLPGEGEEA EAEPMNSDEP EACFTD
Length:1,146
Mass (Da):130,141
Last modified:May 24, 2005 - v1
Checksum:iB955941400F2298E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1146Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108146 Genomic DNA Translation: AAY14794.1
UniGeneiHs.439145

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108146 Genomic DNA Translation: AAY14794.1
UniGeneiHs.439145

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ53QP0
PRIDEiQ53QP0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG2301 Eukaryota
ENOG410XNP6 LUCA
HOVERGENiHBG053100

Miscellaneous databases

ChiTaRSiSCN9A human

Family and domain databases

Gene3Di1.20.120.350, 2 hits
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR010526 Na_trans_assoc
IPR024583 Na_trans_cytopl
IPR028803 SCN9A
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR10037:SF221 PTHR10037:SF221, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 2 hits
PF06512 Na_trans_assoc, 1 hit
PF11933 Na_trans_cytopl, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ53QP0_HUMAN
AccessioniPrimary (citable) accession number: Q53QP0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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