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Entry version 113 (17 Jun 2020)
Sequence version 2 (06 Feb 2007)
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Protein

Coiled-coil domain-containing protein 92

Gene

CCDC92

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

It is uncertain whether Met-1 or Met-18 is the initiator.Curated

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 92
Alternative name(s):
Limkain beta-2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC92
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000119242.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29563 CCDC92

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q53HC0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80212

Open Targets

More...
OpenTargetsi
ENSG00000119242

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA144596459

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q53HC0 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC92

Domain mapping of disease mutations (DMDM)

More...
DMDMi
125863297

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002745001 – 331Coiled-coil domain-containing protein 92Add BLAST331

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q53HC0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q53HC0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q53HC0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q53HC0

PeptideAtlas

More...
PeptideAtlasi
Q53HC0

PRoteomics IDEntifications database

More...
PRIDEi
Q53HC0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
3505
62503 [Q53HC0-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q53HC0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q53HC0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000119242 Expressed in sperm and 228 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q53HC0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q53HC0 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000119242 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
123180, 38 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q53HC0

Protein interaction database and analysis system

More...
IntActi
Q53HC0, 39 interactors

Molecular INTeraction database

More...
MINTi
Q53HC0

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000238156

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q53HC0 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q53HC0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili18 – 44Sequence analysisAdd BLAST27
Coiled coili76 – 152Sequence analysisAdd BLAST77

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIA1 Eukaryota
ENOG410ZQ07 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00430000031027

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_076253_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q53HC0

KEGG Orthology (KO)

More...
KOi
K16452

Identification of Orthologs from Complete Genome Data

More...
OMAi
KPHKAHI

Database of Orthologous Groups

More...
OrthoDBi
1565079at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q53HC0

TreeFam database of animal gene trees

More...
TreeFami
TF329066

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040370 CCDC74A/CCDC74B/CCDC92
IPR033224 CCDC92
IPR039496 CCDC92/74_CC_dom

The PANTHER Classification System

More...
PANTHERi
PTHR14882 PTHR14882, 1 hit
PTHR14882:SF4 PTHR14882:SF4, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14916 CCDC92, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q53HC0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTSPHFSSYD EGPLDVSMAA TNLENQLHSA QKNLLFLQRE HASTLKGLHS
60 70 80 90 100
EIRRLQQHCT DLTYELTVKS SEQTGDGTSK SSELKKRCEE LEAQLKVKEN
110 120 130 140 150
ENAELLKELE QKNAMITVLE NTIKEREKKY LEELKAKSHK LTLLSSELEQ
160 170 180 190 200
RASTIAYLTS QLHAAKKKLM SSSGTSDASP SGSPVLASYK PAPPKDKLPE
210 220 230 240 250
TPRRRMKKSL SAPLHPEFEE VYRFGAESRK LLLREPVDAM PDPTPFLLAR
260 270 280 290 300
ESAEVHLIKE RPLVIPPIAS DRSGEQHSPA REKPHKAHVG VAHRIHHATP
310 320 330
PQAQPEVKTL AVDQVNGGKV VRKHSGTDRT V
Length:331
Mass (Da):36,961
Last modified:February 6, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i840D062480338500
GO
Isoform 2 (identifier: Q53HC0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: Missing.

Show »
Length:314
Mass (Da):35,110
Checksum:iD611C978B87B27A9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H7P8F5H7P8_HUMAN
Coiled-coil domain-containing prote...
CCDC92
96Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H285F5H285_HUMAN
Coiled-coil domain-containing prote...
CCDC92
122Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H2Z7F5H2Z7_HUMAN
Coiled-coil domain-containing prote...
CCDC92
96Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5GXK2F5GXK2_HUMAN
Coiled-coil domain-containing prote...
CCDC92
12Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0J9YWX2A0A0J9YWX2_HUMAN
Coiled-coil domain-containing prote...
CCDC92
17Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD96381 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03030170S → C. Corresponds to variant dbSNP:rs11057401Ensembl.1
Natural variantiVAR_050765253A → T1 PublicationCorresponds to variant dbSNP:rs35935939Ensembl.1
Natural variantiVAR_030302281R → H. Corresponds to variant dbSNP:rs17886730Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0569061 – 17Missing in isoform 2. 1 PublicationAdd BLAST17

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB015292 mRNA Translation: BAB82436.1
AK026124 mRNA Translation: BAB15366.1
AK054680 mRNA Translation: BAG51412.1
AK125866 mRNA Translation: BAG54259.1
AK222661 mRNA Translation: BAD96381.1 Different initiation.
AC068790 Genomic DNA No translation available.
AC079315 Genomic DNA No translation available.
BC017186 mRNA Translation: AAH17186.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS76619.1 [Q53HC0-2]
CCDS9256.1 [Q53HC0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001291886.1, NM_001304957.1 [Q53HC0-1]
NP_001291887.1, NM_001304958.1 [Q53HC0-1]
NP_001291888.1, NM_001304959.1 [Q53HC0-1]
NP_001291889.1, NM_001304960.1 [Q53HC0-1]
NP_001291890.1, NM_001304961.1 [Q53HC0-2]
NP_079416.1, NM_025140.2 [Q53HC0-1]
XP_005253681.1, XM_005253624.2 [Q53HC0-1]
XP_016875473.1, XM_017019984.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000238156; ENSP00000238156; ENSG00000119242 [Q53HC0-1]
ENST00000545135; ENSP00000439526; ENSG00000119242 [Q53HC0-2]
ENST00000545891; ENSP00000440024; ENSG00000119242 [Q53HC0-2]
ENST00000614047; ENSP00000479437; ENSG00000275035 [Q53HC0-2]
ENST00000631749; ENSP00000487695; ENSG00000275035 [Q53HC0-2]
ENST00000632401; ENSP00000488830; ENSG00000275035 [Q53HC0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80212

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80212

UCSC genome browser

More...
UCSCi
uc001ufv.2 human [Q53HC0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB015292 mRNA Translation: BAB82436.1
AK026124 mRNA Translation: BAB15366.1
AK054680 mRNA Translation: BAG51412.1
AK125866 mRNA Translation: BAG54259.1
AK222661 mRNA Translation: BAD96381.1 Different initiation.
AC068790 Genomic DNA No translation available.
AC079315 Genomic DNA No translation available.
BC017186 mRNA Translation: AAH17186.1
CCDSiCCDS76619.1 [Q53HC0-2]
CCDS9256.1 [Q53HC0-1]
RefSeqiNP_001291886.1, NM_001304957.1 [Q53HC0-1]
NP_001291887.1, NM_001304958.1 [Q53HC0-1]
NP_001291888.1, NM_001304959.1 [Q53HC0-1]
NP_001291889.1, NM_001304960.1 [Q53HC0-1]
NP_001291890.1, NM_001304961.1 [Q53HC0-2]
NP_079416.1, NM_025140.2 [Q53HC0-1]
XP_005253681.1, XM_005253624.2 [Q53HC0-1]
XP_016875473.1, XM_017019984.1

3D structure databases

SMRiQ53HC0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi123180, 38 interactors
CORUMiQ53HC0
IntActiQ53HC0, 39 interactors
MINTiQ53HC0
STRINGi9606.ENSP00000238156

PTM databases

iPTMnetiQ53HC0
PhosphoSitePlusiQ53HC0

Polymorphism and mutation databases

BioMutaiCCDC92
DMDMi125863297

Proteomic databases

jPOSTiQ53HC0
MassIVEiQ53HC0
MaxQBiQ53HC0
PaxDbiQ53HC0
PeptideAtlasiQ53HC0
PRIDEiQ53HC0
ProteomicsDBi3505
62503 [Q53HC0-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
52615 114 antibodies

The DNASU plasmid repository

More...
DNASUi
80212

Genome annotation databases

EnsembliENST00000238156; ENSP00000238156; ENSG00000119242 [Q53HC0-1]
ENST00000545135; ENSP00000439526; ENSG00000119242 [Q53HC0-2]
ENST00000545891; ENSP00000440024; ENSG00000119242 [Q53HC0-2]
ENST00000614047; ENSP00000479437; ENSG00000275035 [Q53HC0-2]
ENST00000631749; ENSP00000487695; ENSG00000275035 [Q53HC0-2]
ENST00000632401; ENSP00000488830; ENSG00000275035 [Q53HC0-1]
GeneIDi80212
KEGGihsa:80212
UCSCiuc001ufv.2 human [Q53HC0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80212
DisGeNETi80212
EuPathDBiHostDB:ENSG00000119242.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC92
HGNCiHGNC:29563 CCDC92
HPAiENSG00000119242 Low tissue specificity
neXtProtiNX_Q53HC0
OpenTargetsiENSG00000119242
PharmGKBiPA144596459

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIA1 Eukaryota
ENOG410ZQ07 LUCA
GeneTreeiENSGT00430000031027
HOGENOMiCLU_076253_0_0_1
InParanoidiQ53HC0
KOiK16452
OMAiKPHKAHI
OrthoDBi1565079at2759
PhylomeDBiQ53HC0
TreeFamiTF329066

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
80212 4 hits in 793 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
CCDC92 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
80212
PharosiQ53HC0 Tdark

Protein Ontology

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PROi
PR:Q53HC0
RNActiQ53HC0 protein

Gene expression databases

BgeeiENSG00000119242 Expressed in sperm and 228 other tissues
ExpressionAtlasiQ53HC0 baseline and differential
GenevisibleiQ53HC0 HS

Family and domain databases

InterProiView protein in InterPro
IPR040370 CCDC74A/CCDC74B/CCDC92
IPR033224 CCDC92
IPR039496 CCDC92/74_CC_dom
PANTHERiPTHR14882 PTHR14882, 1 hit
PTHR14882:SF4 PTHR14882:SF4, 1 hit
PfamiView protein in Pfam
PF14916 CCDC92, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCD92_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q53HC0
Secondary accession number(s): B3KNQ0, Q9H697
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: June 17, 2020
This is version 113 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
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