UniProtKB - Q53GL6 (Q53GL6_HUMAN)
Protein
Submitted name:
RNA binding protein (Autoantigenic, hnRNP-associated with lethal yellow) long isoform variant
Gene
RALY
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- identical protein binding Source: IntAct
- RNA binding Source: UniProtKB-UniRule
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: RNA binding protein (Autoantigenic, hnRNP-associated with lethal yellow) long isoform variantImportedSubmitted name: RNA binding protein, autoantigenic (HnRNP-associated with lethal yellow homolog (Mouse))ImportedSubmitted name: RNA binding protein, autoantigenic (HnRNP-associated with lethal yellow homolog (Mouse)), isoform CRA_aImportedSubmitted name: cDNA FLJ77422, highly similar to Homo sapiens RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)), transcript variant 1, mRNAImported |
Gene namesi | Name:RALYImported ORF Names:hCG_37136Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Interactioni
Binary interactionsi
Hide detailsQ53GL6
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
IntActi | Q53GL6, 23 interactors |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 92 | RRMInterPro annotationAdd BLAST | 72 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 215 – 307 | DisorderedSequence analysisAdd BLAST | 93 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 187 – 214 | Sequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 256 – 270 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 272 – 301 | PolyampholyteSequence analysisAdd BLAST | 30 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisARBA annotationFamily and domain databases
CDDi | cd12604, RRM_RALY, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR017347, hnRNP_C IPR012677, Nucleotide-bd_a/b_plait_sf IPR034502, RALY_RRM IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
PIRSFi | PIRSF037992, hnRNP-C_Raly, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q53GL6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLKLQASNV TNKNDPKSIN SRVFIGNLNT ALVKKSDVET IFSKYGRVAG
60 70 80 90 100
CSVHKGYAFV QYSNERHARA AVLGENGRVL AGQTLDINMA GEPKPDRPKG
110 120 130 140 150
LKRAASAIYS GYIFDYDYYR DDFYDRLFDY RGRLSPVPVP RAVPVKRPRV
160 170 180 190 200
TVPLVRRVKT NVPVKLFARS TAVTTSSAKI KLKSSELQAI KTELTQIKSN
210 220 230 240 250
IDALLSRLEQ IAAEQKANPD GKKKGDGGGA SGGGGGGGGS GGGGSGGGGG
260 270 280 290 300
GGSSRPPAPQ ENTTSEAGLP QGEARTRDDG DEEGLLTHSE EELEHSQDTD
ADDGALQ
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC103753 mRNA Translation: AAI03754.1 AK222915 mRNA Translation: BAD96635.1 AK291079 mRNA Translation: BAF83768.1 CH471077 Genomic DNA Translation: EAW76287.1 CH471077 Genomic DNA Translation: EAW76290.1 |
RefSeqi | NP_057951.1, NM_016732.2 |
Genome annotation databases
GeneIDi | 22913 |
KEGGi | hsa:22913 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC103753 mRNA Translation: AAI03754.1 AK222915 mRNA Translation: BAD96635.1 AK291079 mRNA Translation: BAF83768.1 CH471077 Genomic DNA Translation: EAW76287.1 CH471077 Genomic DNA Translation: EAW76290.1 |
RefSeqi | NP_057951.1, NM_016732.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q53GL6, 23 interactors |
Proteomic databases
MaxQBi | Q53GL6 |
PRIDEi | Q53GL6 |
Genome annotation databases
GeneIDi | 22913 |
KEGGi | hsa:22913 |
Organism-specific databases
CTDi | 22913 |
Miscellaneous databases
BioGRID-ORCSi | 22913, 3 hits in 848 CRISPR screens |
ChiTaRSi | RALY, human |
GenomeRNAii | 22913 |
Family and domain databases
CDDi | cd12604, RRM_RALY, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR017347, hnRNP_C IPR012677, Nucleotide-bd_a/b_plait_sf IPR034502, RALY_RRM IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
PIRSFi | PIRSF037992, hnRNP-C_Raly, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q53GL6_HUMAN | |
Accessioni | Q53GL6Primary (citable) accession number: Q53GL6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 24, 2005 |
Last sequence update: | May 24, 2005 | |
Last modified: | December 2, 2020 | |
This is version 131 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |